홍삼에서 추출한 오일의 항산화 및 보습활성
Anti-oxidant Activity of Oil Extracted from Korean Red Ginseng and Its Moisturizing Function
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초록
Korean ginseng (Panax ginseng C.A. Meyer) is one of the most widely used medicinal herbs in the world. Although multiple biological activities of Korean ginseng have been widely studied, anti-oxidant property and moisturizing effect of oil exracted from Korean red ginseng (KRO) remains unknown. Here in vitro anti-oxidant activity and the moisturizing effect in 20-30 aged female of KRO were investigated. The peroxyl radicals are dose-dependently and significantly scavenged by KRO between 0.01-0.1% as judged by ORAC and its electron donating capacity was examined through reduction potential using copper ions. The KRO showed dose-dependent increasing reduction capacity between 0.01% and 0.1%. In addition, the KRO effectively attenuated AAPH- or Cu2+- induced oxidative stress in HepG2 cells. We further investigated the moisturizing effect of KRO in 20-30 aged female for 2 weeks. The treatment of moisturizer with KRO improved moisture content of skin in 20-30 aged female (n=4). These results imply that the KRO may be utilized as strategy for skin. In addition, our findings provide the scientific evidences for the development of skin targeted nutricosmetics and cosmetics.
Abstract
Korean ginseng (Panax ginseng C.A. Meyer) is one of the most widely used medicinal herbs in the world. Although multiple biological activities of Korean ginseng have been widely studied, anti-oxidant property and moisturizing effect of oil exracted from Korean red ginseng (KRO) remains unknown. Here in vitro anti-oxidant activity and the moisturizing effect in 20-30 aged female of KRO were investigated. The peroxyl radicals are dose-dependently and significantly scavenged by KRO between 0.01-0.1% as judged by ORAC and its electron donating capacity was examined through reduction potential using copper ions. The KRO showed dose-dependent increasing reduction capacity between 0.01% and 0.1%. In addition, the KRO effectively attenuated AAPH- or Cu2+- induced oxidative stress in HepG2 cells. We further investigated the moisturizing effect of KRO in 20-30 aged female for 2 weeks. The treatment of moisturizer with KRO improved moisture content of skin in 20-30 aged female (n=4). These results imply that the KRO may be utilized as strategy for skin. In addition, our findings provide the scientific evidences for the development of skin targeted nutricosmetics and cosmetics.
참고문헌 (18)
- 김란, "한방허브추출물을 첨가한 기본제형 크림에 의한 피부보습상태 변화 연구", 대한피부미용학회지, 10(2), pp.399~404 (2012), 대한피부미용학회[DOI]
- 김현정, "효소 처리 홍삼을 함유한 오일의 항산화 효과", 생명과학회지, 18(3), pp.323~328 (2008), 한국생명과학회
- 김형우, "포공영 추출물의 항산화 효과 및 피부 각질세포 보호효과", 대한본초학회지, 24(3), pp.103~108 (2009), 대한본초학회
- 남기열, "홍삼과 백삼의 비교 고찰", Journal of Ginseng Research, 29(1), pp.1~18 (2005), 고려인삼학회
- 박정연, "자가 피부관리가 노인여성의 피부상태 개선과 자아존중감·삶의 만족도에 미치는 영향", 대한피부미용학회지, 10(4), pp.979~984 (2012), 대한피부미용학회
- 백혜연, "홍삼 섭취량에 따른 30대 여성의 안면피부상태 비교", 대한피부미용학회지, 10(4), pp.893~900 (2012), 대한피부미용학회
- 이선영, "이질풀 추출물의 항산화 효능에 관한 연구", 대한화장품학회지, 37(1), pp.61~66 (2011), 대한화장품학회
- 이승현, "γ-cyclodextrin으로 포접한 홍삼추출물의 관능평가 및 Rg1, Rb1의 생체이용율", 한국식품과학회지, 41(1), pp.106~110 (2009), 한국식품과학회
- 조윤희, "영양 그리고 건강기능식품", 식품과학과산업, 38, pp.8~15 (2005)
- 하명희, "진주시 피부관리 고객의 피부건강상태에 관한 통계적 연구", 한국미용학회지, 5, pp.665~679 (1999)
- Curri SB, "Dermocosmetic activity of ginsenosides : Long term evaluation of the moisturizing and tonifying effects on the face skin", Fitoterapia Milano Invemi della Beffa, 57, pp.217~222 (1986)
- Chung S, "γ-Linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs", J. Nutr, 132, pp.3090~3097 (2002)
- Coleman CIJ, "The effect of Panax ginseng in quality of life", J. Clin. Pharm. Ther, 28, pp.5~15 (2003)
- Huang D, "The chemistry behind antioxidant capacity assays", J. Agr. Food Chem, 53, pp.1841~1856 (2005)
- Huang HC, "Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal loos of sodium lauryl sulfate-iffitated skin", Int. J. Dermatol, 47, pp.812~819 (2008)
- Hyo Jung Kim, "Antiobesity Effect of Oil Extract of Ginseng", Journal of Medicinal Food, 14(6), pp.573~583 (2011), 한국식품영양과학회
- 김영란, "자초 추출물 극성 성분의 피부 보습 증진 및 아토피 피부염 호전 효과", 한국식품과학회지, 41(5), pp.547~551 (2009), 한국식품과학회
- Lee EH, "Ginsenoside F1 Protects Human HaCat Keratinocytes from Ultraviolet-B-Induced Apoptosis by Maintaining Constrant Levels of Bcl-2", J. Invest. Dermatol, 121, pp.607~613 (2003)