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IgY 투여에 따른 포유자돈의 설사에 미치는 예방효과Ⅱ. 임상증상, 병리조직학적 검사 및 면역조직학적 검사

Protective effects of IgY against diarrhea in suckling pigletsⅡ. Clinical sign, histopathological lesion and immunohistochemical finding

한정희|윤병일|김문
한국동물위생학회 (THE KOREAN SOCIETY OF VETERINARY SERVICE)|2008.03|한국동물위생학회지|제31권 제1호|pp. 113-128

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참고문헌

키워드

IgYProtective effectPEDVTGEV
주제분류수의학

초록

The purpose of this study was to investigate the protective effects against porcine epidemic diarrhea virus(PEDV) and transmissible gastroenteritis virus(TGEV) in suckling piglets by oral administration of the IgY. The piglets were divided into two groups: test and control group. The former(n=10) were administered orally with IgY for three days from onedayold and experimentally challenged with PEDV and TGEV at fourdayold. The latter(n=10) were administered with saline solution and challenged with same methods. Several tests were studied and summarized as follows;In clinical signs, the piglets of the control group showed the typical signs such as severe watery diarrhea, depression and anorexia but those of the test group recovered progressively. Control group showed 20% in mortality, but there were no death in the other. The gross lesions in the test were milder than those in the control, and there were typical findings as like congestion and distension of lumen in the control group. In histopathological study, the piglets of the cotrol group had shortened and fused intestinal villi and a marked loss of epithelium, whereas the others showed milder changes. It could be concluded that oral administration of IgY, specific yolk-antibody against PEDV and TGEV is effective to prevent PEDV and TGEV infection in suckling piglets.

Abstract

The purpose of this study was to investigate the protective effects against porcine epidemic diarrhea virus(PEDV) and transmissible gastroenteritis virus(TGEV) in suckling piglets by oral administration of the IgY. The piglets were divided into two groups: test and control group. The former(n=10) were administered orally with IgY for three days from onedayold and experimentally challenged with PEDV and TGEV at fourdayold. The latter(n=10) were administered with saline solution and challenged with same methods. Several tests were studied and summarized as follows;In clinical signs, the piglets of the control group showed the typical signs such as severe watery diarrhea, depression and anorexia but those of the test group recovered progressively. Control group showed 20% in mortality, but there were no death in the other. The gross lesions in the test were milder than those in the control, and there were typical findings as like congestion and distension of lumen in the control group. In histopathological study, the piglets of the cotrol group had shortened and fused intestinal villi and a marked loss of epithelium, whereas the others showed milder changes. It could be concluded that oral administration of IgY, specific yolk-antibody against PEDV and TGEV is effective to prevent PEDV and TGEV infection in suckling piglets.

참고문헌 (31)

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