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한국산 약용식물의 안지오텐신 전환효소에 대한 저해활성

Inhibitory Activity on Angiotensin Converting Enzyme (ACE) of Korean Medicinal Herbs

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Abstract

The study was conducted to develop new materials of functional foods from natural resources. Fortyeight medicinal plants were screened on inhibitory activity of angiotensin-converting enzyme (ACE), a protein elevating blood pressure. The water extracts of Armoracia aerial part, Cynanchum tadix, Euonymus branch, Phyllostachys stem, Trichosanthes seed, and methanol extract of Silybum aerial part were showed strong inhibitory activity (above 70%) on ACE at the final concentration of 4,000㎍ㆍ ㎖-¹. Among the plant extracts, water extracts of Phyllostachys taeniam and Trichosanthes seed were especially showed strong inhibitory activity (above 25%) at 500㎍ㆍ㎖-¹. These two plants are expected good candidate for development into anti-hypertensive materials.

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