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마이코플라즈마 폐렴에 동반된 범혈구 감소증 1례

Pancytopenia Associated with Mycoplasma pneumoniae Pneumonia

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참고문헌

키워드

주제분류소아과학

초록

Mycoplasma pnuemoniae는 학동기 소아의 호흡기 감염의 가장 흔한 원인이며 다양한 폐외 증상을 일으키는 것으로 알려져 있다. 이중 혈액학적 이상은 드물게 보고되고 있으며 용혈성 빈혈, 혈소판 감소증, 범혈구 감소증이 생길 수 있다. 저자들은 M. pnuemoniae 폐렴으로 입원 한 뒤 16일 뒤에 발생한 범혈구 감소증을 보인 12세 여아를 경험하였기에 이를 보고하는 바이다.

Abstract

Mycoplasma pneumoniae is the most common pathogen of the respiratory tract among school- aged children and adolescents. It can also cause extrapulmonary manifestation that involves the skin, nervous system, digestive system, and hematopoietic system. A 12-year old girl was admitted to Asan Medical Center Children’s Hospital with M. pneumoniae pneumonia. Her respiratory symptoms and signs improved after the treatment with macrolide antibiotics, and she was discharged. However, pancytopenia developed 16 days after the first admission date. She was readmitted, and treated successfully with intravenous immunoglobulin. We reported her as the first case of pancytopenia asscociated with M. pnuemoniae pneumonia in Korea.

참고문헌 (19)

  1. 김진우, "국내소아에서 발생한 마이코플라스마 폐렴 메타분석", Korean Journal of Pediatrics, 52(3), pp.315~323 (2009), 대한소아과학회
  2. Waites KB, "New concepts of Mycoplasma pneumoniae infections in children", Pediatr Pulmonol, 36, pp.267~278 (2003)
  3. Kottayam R, "Unusual haematologic manifestations of Mycoplasma pneumoniae infection", J Paediatr Child Health, 43, pp.80~82 (2007)
  4. Gursel O, "Mycoplasma pneumoniae infection associated with pancytopenia: a case report", J Pediatr Hematol Oncol, 31, pp.760~762 (2009)
  5. Uldum SA, "Enzyme immunoassay for detection of immunoglobulin M (IgM) and IgG antibodies to Mycoplasma pneumoniae", J Clin Microbiol, 30, pp.1198~1204 (1992)
  6. Gernsheimer T, "Epidemiology and pathophysiology of immune thrombocytopenic purpura", Eur J Haematol Suppl, 69, pp.3~8 (2008)
  7. Talkington DF, "Emerging from obscurity: understanding pulmonary and extrapulmonary syndromes, pathogenesis and epidemiology of human Mycoplasma pneumoniae infections, In Emerging Infections 5", pp.57~84 (2001), American Society for Microbiology Press
  8. Launes J, "Direct invasion of the brain parenchyma by Mycoplasma pneumoniae", Acta Neurol Scand, 95, pp.374~ (1997)
  9. Davis CP, "Isolation of Mycoplasma pneumoniae from synovial fluid samples in a patient with pneumonia and polyarthritis", Arch Intern Med, 148, pp.969~970 (1988)
  10. Okoli K, "Immune thrombocytopenia associated with Mycoplasma pneumoniae infection: a case report and review of literature", Blood Coagul Fibrinolysis, 20, pp.595~598 (2009)
  11. Veenhoven WA, "Thrombocytopenia associated with mycoplasma pneumoniae infection", Neth J Med, 37, pp.75~76 (1990)
  12. Pugliese A, "Mycoplasma pneumoniae induced thrombocytopenia", Heart Lung, 22, pp.373~375 (1993)
  13. Miller SN, "Thrombocytopenia and fatal intracerebral hemorrhage associated with Mycoplasma pneumoniae pneumonia", N Y State J Med, 86, pp.605~607 (1986)
  14. Venkatesan P, "Fatal thrombocytopenia associated with Mycoplasma pneumoniae infection", J Infect, 33, pp.115~117 (1996)
  15. Beattie RM, "Mycoplasma and thrombocytopenia", Arch Dis Child, 68, pp.250~ (1993)
  16. Isoyama K, "Previous Mycoplasma pneumoniae infection causing severe thrombocytopenic purpura", Am J Hematol, 47, pp.252~253 (1994)
  17. Gavanescu I, "Mycoplasma infection induces a scleroderma-like centrosome autoantibody response in mice", Clin Exp Immunol, 137, pp.288~297 (2004)
  18. Stasi R, "Idiopathic thrombocytopenic purpura: current concepts in pathophysiology and management", Thromb Haemost, 99, pp.4~13 (2008)
  19. Zhou B, "Multi-dysfunctional pathophysiology in ITP", Crit Rev Oncol Hematol, 54, pp.107~116 (2005)

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