Use of Porcine-derived Block Bone Substitutes for Guided Bone Regeneration in the Peri-implant Dehiscence Defects of the Mandibular Anterior Region
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Purpose: Various bone graft materials are currently used for guided bone regeneration (GBR), but data are lacking on the superiority of one biomaterial relative to the other. In addition, achieving successful bone augmentation remains challenging. When used in GBR, block bone substitutes show better augmentation stability of the bone than particulated bone substitutes. Recently developed softtype block bone substitutes are widely used in clinical practice. Materials and Methods: This study enrolled 12 patients who underwent implant placement with GBR in the mandibular anterior region between September 2016 and May 2021 in the Department of Periodontology, Daejeon Dental Hospital, Wonkwang University. GBR was performed using demineralized porcine bone mineral with 10% collagen (DPBM-C; LegoGraft®) and a resorbable collagen membrane (Bio-Gide® or Ossix Plus®). The surgical site was sutured with 4-0 e-PTFE (Biotex®) and 5-0 nylon (Monosof®) by using modified horizontal mattress and interrupted suture methods. Stitch-out was performed two weeks af ter the operation, and reentry surgery was performed within four to six months after the implant surgery. Results: There was a significant decrease in bone thickness after five months of implant surgery with GBR compared with the decrease immediately after surgery. However, bone gains of more than 1.5 mm were observed at all measurement sites compared with those at baseline. Conclusion: GBR performed using demineralized porcine bone mineral with 10% collagen in combination with a resorbable collagen membrane is an effective and favorable treatment modality for peri-implant dehiscence defects in terms of clinical and radiographic outcomes during the healing period.
Abstract
Purpose: Various bone graft materials are currently used for guided bone regeneration (GBR), but data are lacking on the superiority of one biomaterial relative to the other. In addition, achieving successful bone augmentation remains challenging. When used in GBR, block bone substitutes show better augmentation stability of the bone than particulated bone substitutes. Recently developed softtype block bone substitutes are widely used in clinical practice. Materials and Methods: This study enrolled 12 patients who underwent implant placement with GBR in the mandibular anterior region between September 2016 and May 2021 in the Department of Periodontology, Daejeon Dental Hospital, Wonkwang University. GBR was performed using demineralized porcine bone mineral with 10% collagen (DPBM-C; LegoGraft®) and a resorbable collagen membrane (Bio-Gide® or Ossix Plus®). The surgical site was sutured with 4-0 e-PTFE (Biotex®) and 5-0 nylon (Monosof®) by using modified horizontal mattress and interrupted suture methods. Stitch-out was performed two weeks af ter the operation, and reentry surgery was performed within four to six months after the implant surgery. Results: There was a significant decrease in bone thickness after five months of implant surgery with GBR compared with the decrease immediately after surgery. However, bone gains of more than 1.5 mm were observed at all measurement sites compared with those at baseline. Conclusion: GBR performed using demineralized porcine bone mineral with 10% collagen in combination with a resorbable collagen membrane is an effective and favorable treatment modality for peri-implant dehiscence defects in terms of clinical and radiographic outcomes during the healing period.
참고문헌 (20)
- Quirynen M, "Implant therapy : 40 years of experience", Periodontol 2000, 66, pp.7~12 (2014)
- Balshi TJ, "A long-term retrospective analysis of survival rates of implants in the mandible", Int J Oral Maxillofac Implants, 30, pp.1348~1354 (2015)
- Simonis P, "Long-term implant survival and success : a 10-16-year followup of non-submerged dental implants", Clin Oral Implants Res, 21, pp.772~777 (2010)
- Howe MS, "Long-term (10-year) dental implant survival: A systematic review and sensitivity meta-analysis", J Dent, 84, pp.9~21 (2019)
- Elgali I, "Guided bone regeneration : materials and biological mechanisms revisited", Eur J Oral Sci, 125, pp.315~337 (2017)
- Cordaro L, "Retrospective evaluation of mandibular incisor replacement with narrow neck implants", Clin Oral Implants Res, 17, pp.730~735 (2006)
- Temmerman A, "The outcome of oral implants placed in bone with limited bucco-oral dimensions : a 3-year follow-up study", J Clin Periodontol, 42, pp.311~318 (2015)
- Benic GI, "Guided bone regeneration of peri-implant defects with particulated and block xenogenic bone substitutes", Clin Oral Implants Res, 27, pp.567~576 (2016)
- Lee JH, "Comparative assessment of anterior maxillary alveolar ridge preservation with and without adjunctive use of enamel matrix derivative: A randomized clinical trial", Clin Oral Implants Res, 31, pp.1~9 (2020)
- Lee JH, "Effect of enamel matrix derivative on alveolar ridge preservation in the posterior maxilla: A randomized controlled clinical trial", Clin Implant Dent Relat Res, 22, pp.622~630 (2020)
- Koo TK, "A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research", J Chiropr Med, 15, pp.155~163 (2016)
- Lee JH, "Assessment of early discomfort and wound healing outcomes after periodontal surgery with and without enamel matrix derivative: an observational retrospective case-control study", Clin Oral Investig, 24, pp.229~237 (2020)
- Wang HL, ""PASS"principles for predictable bone regeneration", Implant Dent, 15, pp.8~17 (2006)
- Benic GI, "block xenogenic bone substitutes : a pilot cone beam computed tomographic investigation", Clin Oral Implants Res, 28, pp.e262~e270 (2017)
- Rakhmatia YD, "Current barrier membranes : titanium mesh and other membranes for guided bone regeneration in dental applications", J Prosthodont Res, 57, pp.3~14 (2013)
- Benic GI, "Horizontal bone augmentation by means of guided bone regeneration", Periodontol 2000, 66, pp.13~40 (2014)
- Mertens C, "The influence of wound closure on graft stability : An in vitro comparison of different bone grafting techniques for the treatment of one-wall horizontal bone defects", Clin Implant Dent Relat Res, 21, pp.284~291 (2019)
- Urban IA, "Vertical Bone Grafting and Periosteal Vertical Mattress Suture for the Fixation of Resorbable Membranes and Stabilization of Particulate Grafts in Horizontal Guided Bone Regeneration to Achieve More Predictable Results: A Technical Report", Int J Periodontics Restorative Dent, 36, pp.153~159 (2016)
- Mir-Mari J, "Influence of blinded wound closure on the volume stability of different GBR materials : an in vitro cone-beam computed tomographic examination", Clin Oral Implants Res, 27, pp.258~265 (2016)
- Jung EH, "Augmentation stability and early wound healing outcomes of guided bone regeneration in peri-implant dehiscence defects with L- and I-shaped soft block bone substitutes:A clinical and radiographic study", Clin Oral Implants Res, 32, pp.1308~1317 (2021)