본문 바로가기
KERD
논문KCI 등재

한국 골퍼 중의 안지오텐신전환효소 유전자의 유전적 다형성

Genetic Polymorphism of the Angiotensin Converting Enzyme Gene among Korean Golfers

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류기타자연과학

초록

.

Abstract

Angiotensin converting enzyme (ACE) is a vital enzyme in the renin-angiotensin-aldosterone system, and there are literature reports describing its relationship between the ACE polymorphism and muscular strength, muscular endurance and flexibility. The purpose of this study is to identify the distribution of the ACE gene polymorphism among individual golfers and the relationship between different golfers group. We analyzed the ACE gene polymorphism to study the individual differences among professional golfers (n=35), junior golfers (n=30) and general golfers (n=25). Genotype frequencies of DD, ID and II in total golfers (n=90) were 16.7%, 52.2% and 31.1% respectively. In professional golfers, the frequencies of DD, ID and II were 25.7%, 45.7% and 28.6% respectively. The frequency of DD genotype in professional golfers was higher than in junior golfers and in general golfers, but the II genotype in professional golfers was lower than in other groups. In conclusion, these data suggest that the capability and power of golf exercise are associated with the hereditary characteristics of the ACE polymorphism.

참고문헌 (24)

  1. Abraham MR, "Angiotensin-converting enzyme genotype modulates pulmonary function and exercise capacity in treated patients with congestive stable heart failure", Circulation, 106(14), pp.1794~1799 (2002)
  2. Alvarez R, "Genetic variation in the renin-angiotensin system and athletic performance", Eur J Appl Physiol, 82, pp.117~120 (2000)
  3. Barley J, "Angiotensin converting enzyme insertion", deletion polymorphism: association with ethnic origin, 1994, pp.12, 955~957
  4. Cambien F, "Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction", Nature, 359, pp.641~644 (1992)
  5. Couture L, "More on red blood cell genetic variation in Olympic athletes", Can J Appl Sport Sci, 11, pp.16~18 (1986)
  6. Danser AH, "Angiotensin-converting enzyme in the human heart. Effect of the deletion", insertion polymorphism, 1995, pp.92, 1387~1388
  7. Gayagay G, "Elite endurance athletes and the ACE I allelethe role of genes in athletic performance", Hum Genet, 103, pp.48~50 (1998)
  8. 김기진, "성인여성의 ACE 유전자 다형성에 따른 건강관련체력 특성 비교", 한국발육발달학회지, 15(3), pp.147~153 (2007), 한국발육발달학회
  9. Malik FS, "Reninangiotensin system: genes to bedside", Am Heart J, 134, pp.514~526 (1997)
  10. McBride TA, "AT1 receptors are necessary for eccentric training-induced hypertrophy and strength gains in rat skeletal muscle", Exp Physiol, 91, pp.413~421 (2006)
  11. Montgomery HE, "Human gene for physical performance", Nature, 393, pp.221~222 (1998)
  12. Myerson S, "Human angiotensin I-converting enzyme gene and endurance performance", J Appl Physiol, 87, pp.1313~1316 (1999)
  13. Nazarov IB, "The angiotensin converting enzyme I", D polymorphism in Russian athletes, 2001, pp.9, 797~801
  14. Pérusse L, "The human gene map for performance and health-related fitness phenotypes: the 2002 update", Med Sci Sports Exerc, 35, pp.1248~1264 (2003)
  15. Rankinen T, "The human gene map for performance and health-related fitness phenotypes", Med Sci Sports Exerc, 33, pp.855~867 (2001)
  16. Rankinen T, "No association between the angiotensin-converting enzyme ID polymorphism and elite endurance athlete status", J Appl Physiol, 88, pp.1571~1575 (2000)
  17. Rigat B, "An insertion", deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels, 1990, pp.86, 1343~1346
  18. Rigat B, "PCR detection of the insertion", deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1), 1992, pp.20, 1433~
  19. Silva GJ, "ACE gene dosage modulates pressure-induced cardiac hypertrophy in mice and men", Physiol Genomics, 27, pp.237~244 (2006)
  20. Stevenson JS, "Effects of moderate and low intensity long-term exercise by older adults", Res Nurs Health, 13, pp.209~218 (1990)
  21. Taylor RR, "Elite athletes and the gene for angiotensin-converting enzyme", J Appl Physiol, 87, pp.1035~1037 (1999)
  22. Uemura K, "Deletion polymorphism of ACE gene is associated with higher blood pressure after hospitalization in normotensive subjects", Hypertens Res, 23, pp.201~205 (2000)
  23. Woods DR, "The ACE I", D polymorphism and human physical performance, 2000, pp.11, 416~420
  24. Woods DR, "Endurance enhancement related to the human angiotensin I-converting enzyme I-D polymorphism is not due to differences in the cardiorespiratory response to training", Eur J Appl Physiol, 86, pp.240~244 (2002)

관련 논문AI추천

이 간행물의 다른 논문 (6건)