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유기발광다이오드를 이용한 Photobiomodulation 기반 스킨케어 효과

Photobiomodulation-based Skin-care Effect of Organic Light-emitting Diodes

정혜정|이병일|안재성|김홍빈|진석근
한국광학회|2021.10|한국광학회지 (Korean Journal of Optics and Photonics)|제32권 제5호|pp. 235-243

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키워드

PhotobiomodulationOrganic light-emitting diodes저출력광치료광생물조절Low-level light therapy유기발광다이오드피부관리효과Skin care effect
주제분류물리학

초록

Photobiomodulation (PBM) 치료법은 특정 파장대역의 광원이 미토콘드리아에서 ATP 생성을 촉진하는 현상을 이용하는 치료법으로서 상처 치유, 염증 감소, 통증 완화 효과가 있는 것으로 알려져 생물 및 의학 분야에서 많은 관심을 받고 있다. PBM 치료법에 대한 연구는 주로 레이 저, 발광다이오드(LED)를 광원으로 사용하였고, 유기발광다이오드(OLED)가 가지는 장점에도 불구하고 PBM 치료법에 사용된 사례는 제한적이 다. 본 연구에서는 적색(λ = 620 nm), 녹색(λ = 525 nm), 청색(λ = 455 nm) OLED 조명모듈을 사용하여 PBM에 의한 피부관리 효과를 분석하고 LED에 의한 PBM 효과와 비교하였다. OLED 조명모듈의 PBM에 의한 피부미용효과는 적색 OLED 조명모듈에 의한 collagen type 1 합성량 증가, 녹색 OLED 조명모듈에 의한 melanin 합성 억제, 청색 OLED 조명모듈에 의한 nitric oxide 생성 억제를 각각 측정하여 입증되었다.

Abstract

Photobiomodulation (PBM)-based therapy, which uses a phenomenon in which a light source of a specific wavelength band promotes ATPproduction in mitochondria, has attracted much attention in the fields of biology and medicine because of its effects on wound healing, inflammationreduction, and pain relief. Research on PBM-based therapy has mainly used lasers and light-emitting diodes (LEDs) as light sources and, despite the advantages of organic light-emitting diodes (OLEDs), there have been only a few cases where OLEDs were used in PBM-based therapy. In this research, the skin-care effect of PBM was analyzed using red (λ = 620 nm), green (λ = 525 nm), and blue (λ = 455 nm) OLED lighting modules, and was compared to the PBM effect of LEDs. We demonstrated the PBM-based skin-care effect of the red, green, blue OLED lighting modules by measuringthe increase in the amount of collagen type-1 synthesis, the inhibition of melanin synthesis, and the suppression of nitric oxide generation respectively.

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