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정신증 유무에 따른 K-WAIS-IV 프로파일의 하위유형과 임상적 특성: 탐색적 연구

K-WAIS-IV Profiles and Their Clinical Correlates in Psychiatric Patients With/Without Psychotic Symptoms: An Exploratory Study

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초록

본 연구는 사례중심적 접근을 통해 정신과 내원 환자들의 K-WAIS-IV 프로파일의 하위유형을 탐색하고 정신증 유무에 따른 하위유형의임상적 특성을 확인하고자 하였다. 이를 위해 218명의 정신증적 장애 환자(조현병 및 정신증을 동반한 기분장애)와 232명의 정신증을 동반하지 않은 기분장애 환자들 각각에 대하여 K-WAIS-IV 지표점수 및 전체 지능지수에 대한 잠재 프로파일 분석을 실시하였으며, 도출된하위집단의 MMPI-2-RF 점수를 비교하였다. 잠재 프로파일 분석 결과, 정신증적 장애군과 비정신증적 장애군 모두 ‘전반적 손상 집단’ , ‘선택적 손상 집단’ , ‘정상 집단’으로 구성된 3계층 모형이 가장 적합한 것으로 나타났다. 그러나 ‘선택적 손상 집단’에서 관찰되는 손상 영역은정신증 유무에 따라 상이하였는데, 정신증적 장애군은 언어이해를 제외한 모든 지표가 저하되었던 반면, 비정신증적 장애군은 언어이해와 함께 작업기억 지표 또한 유지되는 점이 특징적이었다. 임상적 특성과 관련하여서는 일반적으로 인지기능 손상이 전반적일수록, 그리고정신증적 장애군보다는 비정신증적 장애군일 때 더 높은 수준의 증상을 호소하는 양상이었으나, 일부 임상적 특성의 경우 정신증 유무에따라 하위집단 간 증상 호소의 양상이 달라짐을 확인할 수 있었다. 이러한 결과를 토대로 본 연구결과의 시사점과 한계점에 관하여 논의하였다.

Abstract

The purpose of this study was to explore the subgroups of K-WAIS-IV profiles among psychiatric patients with and without psychotic symptoms using a data-driven approach and to identify their clinical characteristics. Latent profile analyses were conducted using K-WAIS-IV performance data from 218 patients with psychotic disorders and 232 patients with non-psy￾chotic affective disorders. Subgroups were then compared on their MMPI-2-RF scores, diagnosis, and demographic vari￾ables. A three-cluster solution including a “cognitively normal,” a “selectively impaired,” and a “globally impaired” group was selected for both psychotic and non-psychotic patients. However, the profiles of the selectively impaired group differed be￾tween the psychotic and non-psychotic patients. In psychotic patients, the selectively impaired group showed lowered perfor￾mance on general intelligence and all other index scores except for VCI, while the non-psychotic patients showed average performance on WMI as well as VCI. Regarding the MMPI-2-RF results, in general, patients with more pervasive cognitive impairment and those with psychotic disorders rather than non-psychotic disorders tended to report significantly higher scores across various scales. However, on some scales, the profiles of subgroups were found to differ between psychotic and non-psychotic patients. Based on these results, the implications and limitations of the study are discussed.

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