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양극성장애 환자의 K-WAIS-Ⅳ 프로파일 분석

Analysis on the K-WAIS-Ⅳ Profile of the Patients with Bipolar Disorder

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참고문헌

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초록

본 연구의 목적은 Wechsler 지능 검사의 최신판인 K-WAIS-Ⅳ를 활용하여 양극성장애 환자와 정상통제군의 인지적 수행 수준을 비교함으로써 양극성장애 환자의 인지기능 상의 특징을 파악하고자 하는 것이다. 또한 임상적인 변인에 해당하는 발병 연령, 유병 기간, 이전에 경험한 삽화 횟수, 입원 횟수 및 기분 증상의 심각도와 인기기능 수준의 관계를 파악하고자 하였다. 58명의 양극성장애 환자와 300명의 정상통제군을 대상으로 K-WAIS-Ⅳ를 실시하여 두 집단의 전체지능지수, 4개의 하위 지수 점수, 10개의 핵심 소검사 환산 점수를 비교하였다. 그 결과 양극성장애 환자는 정상통제군과 비교할 때 전체지능지수, 작업기억, 처리속도지수에서 유의하게 저조한 수행을 보였고, 특히 처리속도지수에서의 수행이 매우 유의하게 저조한 것으로 나타났다. 또한 작업기억과 처리속도지수의 소검사인 숫자, 산수, 동형찾기, 기호쓰기 소검사에서의 수행이 매우 저조한 것으로 나타났다. 이러한 결과는 양극성장애 환자에게서 인지기능 상의 비효율성이 나타남을 시사한다. 그러나 임상적인 변인과 전체지능지수 및 4가지 하위 지수 사이에는 유의한 상관관계는 관찰되지 않았다.

Abstract

The current study was conducted to compare the level of cognitive functioning in patients with bipolar disorder by utilizing the brand-new version of the Wechsler intelligence scale, K-WAIS-Ⅳ, and to understand their cognitive characteristics by comparing the bipolar patients group and the normal control group(NC). In addition, the purpose of this study was to understand the relation between cognitive functioning and clinical variables including the age of onset, the length of disorder, the number of mood episodes, the number of previous hospitalizations, and the severity of mood symptoms. K-WAIS-Ⅳ was performed for 58 bipolar patients and 300 people from NC for comparison of their Full Scale IQ(FSIQ), 4 index scaled scores, and 10 scaled scores of subtests. Bipolar patients showed significantly lower performance on FSIQ, working memory index(WMI), and processing speed index(PSI) when compared to NC, and, in particular, they showed the lowest performances on PSI. The performances in digit span, arithmetic, symbol search, and coding, the subtests of WMI and PSI were also significantly poor. These results imply cognitive inefficiency in patients with bipolar disorder. However, no significant correlations were observed among the clinical variables and the FSIQ, four indices.

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