Combined effect of anemia and chronic rhinitis on hearing loss in Korean adults: a nationwide observational study
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OBJECTIVES: Studies have suggested an association between hearing loss and anemia. Hearing loss has also been linked to rhinitis, which is characterized by inflammation of the nasal mucous membranes and sinus mucosa. Few studies have concurrently explored the relationships between hearing loss, anemia, and rhinitis. This study was conducted to investigate the association between hearing loss and anemia and to further analyze the potential role of rhinitis in this relationship.METHODS: Data were collected from the 2020 Korea National Health and Nutrition Examination Survey. Hearing loss was measured with an audiometer in a soundproof booth and was defined as at least moderate impairment (as indicated by a pure-tone average of ≥41 dB in the better-hearing ear). The association between hearing loss and anemia was analyzed using multivariable logistic regression. The combined effect of anemia and rhinitis on hearing loss was assessed with an interaction term.RESULTS: Among the 2,772 participants, 477 (17.2%) exhibited hearing loss. Participants with anemia were more likely to experience hearing loss than those without anemia (odds ratio [OR], 1.58; 95% confidence interval [CI], 1.07 to 2.33). Furthermore, the odds of hearing loss were greater in participants with both anemia and rhinitis (OR, 3.79; 95% CI, 1.93 to 7.43) relative to those without either condition.CONCLUSIONS: Anemia was associated with hearing loss in individuals aged 40 years and older. Based on the analysis of combined effects, participants with anemia and chronic rhinitis were more likely to experience hearing loss than individuals without these conditions.
Abstract
OBJECTIVES: Studies have suggested an association between hearing loss and anemia. Hearing loss has also been linked to rhinitis, which is characterized by inflammation of the nasal mucous membranes and sinus mucosa. Few studies have concurrently explored the relationships between hearing loss, anemia, and rhinitis. This study was conducted to investigate the association between hearing loss and anemia and to further analyze the potential role of rhinitis in this relationship.METHODS: Data were collected from the 2020 Korea National Health and Nutrition Examination Survey. Hearing loss was measured with an audiometer in a soundproof booth and was defined as at least moderate impairment (as indicated by a pure-tone average of ≥41 dB in the better-hearing ear). The association between hearing loss and anemia was analyzed using multivariable logistic regression. The combined effect of anemia and rhinitis on hearing loss was assessed with an interaction term.RESULTS: Among the 2,772 participants, 477 (17.2%) exhibited hearing loss. Participants with anemia were more likely to experience hearing loss than those without anemia (odds ratio [OR], 1.58; 95% confidence interval [CI], 1.07 to 2.33). Furthermore, the odds of hearing loss were greater in participants with both anemia and rhinitis (OR, 3.79; 95% CI, 1.93 to 7.43) relative to those without either condition.CONCLUSIONS: Anemia was associated with hearing loss in individuals aged 40 years and older. Based on the analysis of combined effects, participants with anemia and chronic rhinitis were more likely to experience hearing loss than individuals without these conditions.
참고문헌 (26)
- Im GJ, "Prevalence of severe-profound hearing loss in South Korea : a nationwide population-based study to analyse a 10-year trend(2006-2015)", Sci Rep, 8, pp.9940~ (2018)[DOI]
- Stevens G, "Global and regional hearing impairment prevalence : an analysis of 42 studies in 29 countries", Eur J Public Health, 23, pp.146~152 (2013)[DOI]
- Li Y, "Increasing obstructive sleep apnea risk is associated with hearing impairment in middle-aged Chinese men-a cross-sectional study", PLoS One, 17, pp.e0268412~ (2022)[DOI]
- Dalton DS, "The impact of hearing loss on quality of life in older adults", Gerontologist, 43, pp.661~668 (2003)[DOI]
- Dawes P, "Hearing loss and cognition : the role of hearing AIDS, social isolation and depression", PLoS One, 10, pp.e0119616~ (2015)[DOI]
- Stucken EZ, "Noise-induced hearing loss : an occupational medicine perspective", Curr Opin Otolaryngol Head Neck Surg, 22, pp.388~393 (2014)[DOI]
- Cohen BE, "Viral causes of hearing loss : a review for hearing health professionals", Trends Hear, 18, pp.2331216514541361~ (2014)[DOI]
- Chopra A, "Sleep apnea is associated with hearing impairment : the Hispanic community health study", study of Latinos, 2016, pp.12, 719~726
- Kassebaum NJ, "A systematic analysis of global anemia burden from 1990 to 2010", Blood, 123, pp.615~624 (2014)[DOI]
- Iglesias Vázquez L, "Prevalence of anemia in children from Latin America and the Caribbean and effectiveness of nutritional interventions : systematic review and meta-analysis", Nutrients, 11, pp.183~ (2019)[DOI]
- Schieffer KM, "Association of iron deficiency anemia with hearing loss in US adults", JAMA Otolaryngol Head Neck Surg, 143, pp.350~354 (2017)[DOI]
- Scadding GK, "Clinical respiratory medicine", pp.409~423 (2008), Elsevier
- Drury KE, "Association between atopic disease and anemia in US children", JAMA Pediatr, 170, pp.29~34 (2016)[DOI]
- Lee SA, "National representative analysis of unilateral hearing loss and hearing aid usage in South Korea", PLoS One, 15, pp.e0232112~ (2020)[DOI]
- Gi YM, "Low handgrip strength is closely associated with anemia among adults : a cross-sectional study using Korea National Health and Nutrition Examination Survey(KNHANES)", PLoS One, 15, pp.e0218058~ (2020)[DOI]
- Mohammed SH, "Association of anemia with sensorineural hearing loss : a systematic review and meta-analysis", BMC Res Notes, 12, pp.283~ (2019)[DOI]
- Kim SY, "Sudden sensorineural hearing loss associated with nutritional anemia : a nested case-control study using a National Health Screening Cohort", Int J Environ Res Public Health, 17, pp.6478~ (2020)[DOI]
- Zhang C, "Essential functions of iron-requiring proteins in DNA replication, repair and cell cycle control", Protein Cell, 5, pp.750~760 (2014)[DOI]
- Badaracco ME, "Effect of transferrin on hypomyelination induced by iron deficiency", J Neurosci Res, 86, pp.2663~2673 (2008)[DOI]
- Dwarakanath VM, "Assessment of hearing in individuals with allergic rhinitis", Indian J Otol, 25, pp.117~120 (2019)[DOI]
- Acharya S, "Study of incidence of sensorineural hearing loss in allergic rhinitis", Int J Otorhinolaryngol Head Neck Surg, 8, pp.228~231 (2022)[DOI]
- Singh S, "Audiological manifestations of allergic rhinitis", J Laryngol Otol, 125, pp.906~910 (2011)[DOI]
- Petje LM, "Functional iron-deficiency in women with allergic rhinitis is associated with symptoms after nasal provocation and lack of iron-sequestering microbes", Allergy, 76, pp.2882~2886 (2021)[DOI]
- Yang L, "Allergic disorders and risk of anemia in Japanese children : findings from the Japan environment and children’s study", Nutrients, 14, pp.4335~ (2022)[DOI]
- McManus B, "Otoscopy and tympanometry outcomes from the National Health and Nutrition Examination Survey(NHANES)", Am J Otolaryngol, 43, pp.103332~ (2022)[DOI]
- Kim S, "Age-related hearing loss in the Korea National Health and Nutrition Examination Survey", PLoS One, 15, pp.e0243001~ (2020)[DOI]