Characteristics of Hearing Loss Among Older Adults in the Korean Genome and Epidemiology Study: A Community-Based Longitudinal Cohort Study With an 8-Year Follow-up
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives. This study investigated the 8-year incidence and progression of hearing loss (HL) and its types and examinedthe risk factors for changes in HL. Methods. This longitudinal cohort study analyzed data from the Korean Genome and Epidemiology Study (KoGES), anongoing, prospective, community-based cohort study that has been conducted since 2001. Altogether, 1,890 residentsof urban areas in Korea aged 45–75 years at time 1 (baseline) were included in the study. Pure-tone audiometry(PTA) testing was performed twice, at time 1 (2008–2009) and time 2 (2015–2018, follow-up), 8 years apart. HLgrades were defined as seven mutually exclusive categories following the revised World Health Organization classifi-cation. Incidence was defined as PTA >20 dB HL in the better ear at time 2 among those without HL at time 1. Pro-gression was defined as the progressive deterioration of HL among those with HL at time 1. The three types of HLconstituted sensorineural (SNHL), conductive, and mixed HL. Results. At time 1, 36.40% of patients were diagnosed with HL, which increased to 51.64% at time 2. The 8-year incidenceof HL was 27.20%, and progressive deterioration of HL occurred in 23.11% of those with HL. SNHL was the mostcommon type of HL, and its prevalence markedly increased at time 2. Multivariate analysis demonstrated that the in-cidence of HL was significantly associated with increasing age, male sex (odds ratio [OR], 1.73; 95% confidence in-terval [CI], 1.07–2.81), and diabetes mellitus (OR, 1.43; 95% CI, 1.04–1.96). Alcohol consumption was a risk factorfor HL deterioration among those with HL at time 1. Conclusion. The prevalence and deterioration of HL were extremely high among older adults, and age was the strongestrisk factor for these changes. Therefore, timely screening and intervention are necessary to prevent HL and delay itsdeterioration among older adults.
Abstract
Objectives. This study investigated the 8-year incidence and progression of hearing loss (HL) and its types and examinedthe risk factors for changes in HL. Methods. This longitudinal cohort study analyzed data from the Korean Genome and Epidemiology Study (KoGES), anongoing, prospective, community-based cohort study that has been conducted since 2001. Altogether, 1,890 residentsof urban areas in Korea aged 45–75 years at time 1 (baseline) were included in the study. Pure-tone audiometry(PTA) testing was performed twice, at time 1 (2008–2009) and time 2 (2015–2018, follow-up), 8 years apart. HLgrades were defined as seven mutually exclusive categories following the revised World Health Organization classifi-cation. Incidence was defined as PTA >20 dB HL in the better ear at time 2 among those without HL at time 1. Pro-gression was defined as the progressive deterioration of HL among those with HL at time 1. The three types of HLconstituted sensorineural (SNHL), conductive, and mixed HL. Results. At time 1, 36.40% of patients were diagnosed with HL, which increased to 51.64% at time 2. The 8-year incidenceof HL was 27.20%, and progressive deterioration of HL occurred in 23.11% of those with HL. SNHL was the mostcommon type of HL, and its prevalence markedly increased at time 2. Multivariate analysis demonstrated that the in-cidence of HL was significantly associated with increasing age, male sex (odds ratio [OR], 1.73; 95% confidence in-terval [CI], 1.07–2.81), and diabetes mellitus (OR, 1.43; 95% CI, 1.04–1.96). Alcohol consumption was a risk factorfor HL deterioration among those with HL at time 1. Conclusion. The prevalence and deterioration of HL were extremely high among older adults, and age was the strongestrisk factor for these changes. Therefore, timely screening and intervention are necessary to prevent HL and delay itsdeterioration among older adults.
참고문헌 (29)
- "WHO: 1 in 4 people projected to have hearing problems by 2050" (2021)[URL]
- Agrawal Y, "Risk factors for hearing loss in US adults : data from the National Health and Nutrition Examination Survey, 1999 to 2002", Otol Neurotol, 30(2), pp.139~145 (2009)
- Ward WD, "Endogenous factors related to susceptibility to damage from noise", Occup Med, 10(3), pp.561~575 (1995)
- Contrera KJ, "Association of hearing impairment and mortality in the National Health and Nutrition Examination Survey", JAMA Otolaryngol Head Neck Surg, 141(10), pp.944~946 (2015)
- Lawrence BJ, "Hearing loss and depression in older adults : a systematic review and meta-analysis", Gerontologist, 60(3), pp.e137~54 (2020)
- Mick P, "The association between hearing loss and social isolation in older adults", Otolaryngol Head Neck Surg, 150(3), pp.378~384 (2014)
- Pronk M, "Hearing status in older persons : a significant determinant of depression and loneliness? : results from the longitudinal aging study amsterdam", Am J Audiol, 22(2), pp.316~320 (2013)
- Sung YK, "Association of hearing loss and loneliness in older adults", J Aging Health, 28(6), pp.979~994 (2016)
- Liu CM, "Association of hearing loss with dementia", JAMA Netw Open, 2(7), pp.e198112~ (2019)
- Loughrey DG, "Association of age-related hearing loss with cognitive function, cognitive impairment, and dementia : a systematic review and meta-analysis", JAMA Otolaryngol Head Neck Surg, 144(2), pp.115~126 (2018)
- Tseng YC, "Quality of life in older adults with sensory impairments : a systematic review", Qual Life Res, 27(8), pp.1957~1971 (2018)
- Nolan LS, "Age-related hearing loss : why we need to think about sex as a biological variable", J Neurosci Res, 98(9), pp.1705~1720 (2020)
- Cruickshanks KJ, "The 5-year incidence and progression of hearing loss : the epidemiology of hearing loss study", Arch Otolaryngol Head Neck Surg, 129(10), pp.1041~1046 (2003)
- Homans NC, "Prevalence of age-related hearing loss, including sex differences, in older adults in a large cohort study", Laryngoscope, 127(3), pp.725~730 (2017)
- Cruickshanks KJ, "Prevalence of hearing loss in older adults in Beaver Dam, Wisconsin : the Epidemiology of Hearing Loss Study", Am J Epidemiol, 148(9), pp.879~886 (1998)
- Wilson BS, "Global hearing health care : new findings and perspectives", Lancet, 390(10111), pp.2503~2515 (2017)
- "Deafness and hearing loss" (2021)[URL]
- Stevens G, "Global and regional hearing impairment prevalence : an analysis of 42 studies in 29 countries", Eur J Public Health, 23(1), pp.146~152 (2013)
- Lin FR, "Hearing loss prevalence and risk factors among older adults in the United States", J Gerontol A Biol Sci Med Sci, 66(5), pp.582~590 (2011)
- GBD 2019 Hearing Loss Collaborators, "Hearing loss prevalence and years lived with disability, 1990-2019 : findings from the Global Burden of Disease Study 2019", Lancet, 397(10278), pp.996~1009 (2021)
- Kim Y, "Cohort profile : The Korean Genome and Epidemiology Study(KoGES)Consortium", Int J Epidemiol, 46(2), pp.e20~ (2017)
- Olusanya BO, "Hearing loss grades and the international classification of functioning, disability and health", Bull World Health Organ, 97(10), pp.725~728 (2019)
- Ainsworth BE, "Compendium of physical activities : an update of activity codes and MET intensities", Med Sci Sports Exerc, 32(9 Suppl), pp.S498~504 (2000)
- Mitchell P, "Five-year incidence and progression of hearing impairment in an older population", Ear Hear, 32(2), pp.251~257 (2011)
- Karlsmose B, "A five-year longitudinal study of hearing in a Danish rural population aged 31-50 years", Br J Audiol, 34(1), pp.47~55 (2000)
- Pirila T, "Left-right asymmetries in hearing threshold levels in three age groups of a random population", Audiology, 31(3), pp.150~161 (1992)
- Moscicki EK, "Hearing loss in the elderly : an epidemiologic study of the Framingham Heart Study Cohort", Ear Hear, 6(4), pp.184~190 (1985)
- Lin FR, "Hearing loss prevalence in the United States", Arch Intern Med, 171(20), pp.1851~1852 (2011)
- Wild DC, "Noise-induced hearing loss is exacerbated by long-term smoking", Clin Otolaryngol, 30(6), pp.517~520 (2005)