Analysis of Reporting Time for Identification of Methicillin-Resistant Staphylococcus aureus Carriers Using ChromID MRSA
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We assessed the reporting times for identification of nasal methicillin-resistant Staphylococ- cus aureus (MRSA) carriers in 2011 in a university-affiliated hospital using surveillance cul- tures incubated for 1 and 2 days with ChromID MRSA (bioMérieux, France). Of 2,732 na- sal swabs tested, MRSA was detected in 829 (85.6%) and 140 (14.4%) swabs after 1 and 2 days of incubation, respectively, and the median reporting times for positive specimens were 33.7 hr (range, 18.2-156.9 hr) and 108.1 hr (range, 69.8-181.0 hr), respectively. De- tection rate after 1-day incubation was 85%. Additional 1-day incubation improved detec- tion rate; however, it prolonged the reporting times of positive specimens approximately up to 4 days because of the need for confirmatory tests such as species identification and sus- ceptibility tests. Following a 2-day culture with ChromID MRSA, rapid confirmatory tests are warranted to reduce delay in identifying MRSA carriers.
Abstract
We assessed the reporting times for identification of nasal methicillin-resistant Staphylococ- cus aureus (MRSA) carriers in 2011 in a university-affiliated hospital using surveillance cul- tures incubated for 1 and 2 days with ChromID MRSA (bioMérieux, France). Of 2,732 na- sal swabs tested, MRSA was detected in 829 (85.6%) and 140 (14.4%) swabs after 1 and 2 days of incubation, respectively, and the median reporting times for positive specimens were 33.7 hr (range, 18.2-156.9 hr) and 108.1 hr (range, 69.8-181.0 hr), respectively. De- tection rate after 1-day incubation was 85%. Additional 1-day incubation improved detec- tion rate; however, it prolonged the reporting times of positive specimens approximately up to 4 days because of the need for confirmatory tests such as species identification and sus- ceptibility tests. Following a 2-day culture with ChromID MRSA, rapid confirmatory tests are warranted to reduce delay in identifying MRSA carriers.
참고문헌 (12)
- Cosgrove SE, "Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis", Clin Infect Dis, 36, pp.53~59 (2003)
- Engemann JJ, "Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection", Clin Infect Dis, 36, pp.592~598 (2003)
- 이혁민, "2005∼2006년 국내 12개 병원에서 분리된 주요 세균의 항균제 내성률", Annals of Clinical Microbiology, 10(1), pp.59~69 (2007), 대한임상미생물학회
- Tacconelli E, "Rapid screening tests for meticillin-resistant Staphylococcus aureus at hospital admission: systematic review and meta-analysis", Lancet Infect Dis, 9, pp.546~554 (2009)
- Harbarth S, "Update on screening and clinical diagnosis of meticillin-resistant Staphylococcus aureus (MRSA)", Int J Antimicrob Agents, 37, pp.110~117 (2011)
- Malhotra-Kumar S, "Current trends in rapid diagnostics for methicillin-resistant Staphylococcus aureus and glycopeptide-resistant enterococcus species", J Clin Microbiol, 46, pp.1577~1587 (2008)
- Wassenberg MW, "Rapid screening of methicillin-resistant Staphylococcus aureus using PCR and chromogenic agar: a prospective study to evaluate costs and effects", Clin Microbiol Infect, 16, pp.1754~1761 (2010)
- Morris K, "Evaluation of chromogenic meticillin-resistant Staphylococcus aureus media: sensitivity versus turnaround time", J Hosp Infect, 81, pp.20~24 (2012)
- Carson J, "Interpretation of MRSASelect screening agar at 24 hours of incubation", J Clin Microbiol, 47, pp.566~568 (2009)
- Nahimana I, "Evaluation of three chromogenic media (MRSA-ID, MRSA-Select and CHROMagar MRSA) and ORSAB for surveillance cultures of methicillin-resistant Staphylococcus aureus", Clin Microbiol Infect, 12, pp.1168~1174 (2006)
- Nonhoff C, "Comparison of three chromogenic media and enrichment broth media for the detection of methicillin-resistant Staphylococcus aureus from mucocutaneous screening specimens: comparison of MRSA chromogenic media", Eur J Clin Microbiol Infect Dis, 28, pp.363~369 (2009)
- Van Hoecke F, "Performance evaluation of a modified chromogenic medium, ChromID MRSA New, for the detection of methicillin-resistant Staphylococcus aureus from clinical specimens", Eur J Clin Microbiol Infect Dis, 30, pp.1595~1598 (2011)