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노화에 따른 개의 트레드밀 운동 시 생리학적·혈액학적 반응 비교

Comparison of physiological and hematological responses to treadmill exercise in younger and older adult dogs

오현주|김진욱|이석희|김종희|이해성
국민체육진흥공단 한국스포츠과학원 (Korea Institute of Sport Science)|2019.12|체육과학연구 (Korean Journal of Sport Science)|제30권 제4호|pp. 677-688|DOI 10.24985/kjss.2019.30.4.677

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참고문헌

키워드

aging노화심박수heart rate개dog트레드밀 운동treadmill exercise심박수 회복 시간heart rate recovery time
주제분류체육

초록

[목적] 본 연구의 목적은 성견과 노견을 대상으로 트레드밀 운동 시 심박수 반응을 비교하여, 노화에 따른 심혈관계 시스템의 변화를 평가하고, 운동생리학적 접근을 통한 노화 모델로서 개의 가치를 검증하는 데 있다. [방법] 연구대상은 건강한 비글 11두가 참여하였고, 연령에 따라 성견(1~2세) 7두와 노견(9~11세) 4두로 분류하였다. 트레드밀 운동은 주 2회 반복 실시하여 4주간 진행하였고, 네 개의 다른 프로토콜을 적용해 운동강도를 점진적으로 증가시켰다. 심박수 변인과 혈액학적 변인의 평가는 독립 t-검정과 일원분산분석을 통해 실시하였고, 연령과 심박수 반응, 심박수 회복 시간 간의 상관성은 Spearman’s 상관분석을 통해 검증하였다. [결과] 본 연구의 결과, 노견은 성견보다 안정 시, 운동 중 심박수가 유의하게 높았으며, 운동 후 심박수 회복 시간도 유의한 차이가 있는 것으로 나타났다. 비글의 연령과 안정 시, 운동 중 심박수, 심박수 회복 시간 간에 강한 양의 상관관계를 확인하였다. 또한, 성견과 노견 모두 운동 강도의 증가에도 불구하고 1주차와 4주차의 운동 중 심박수 반응에는 차이가 없었다. 운동은 노견의 백혈구 수치를 낮추고, 성견의 ALP 수준을 증가시키는 효과를 나타냈다. [결론] 단기 트레드밀 운동은 개의 유산소성 능력, 염증반응 및 골 형성에 긍정적인 효과가 있는 것으로 사료되며, 본 연구는 운동 과학 연구에서 노화 모델로서 개의 가치를 시사하는 바이다.

Abstract

[Purpose] The purpose of this study was to investigate changes of the cardiovascular system by comparing heart rate (HR) and blood responses to exercise in younger and older adult dogs and to verify the value of dogs as aging model in exercise science research. [Methods] A total of 11 healthy beagles were divided into 2 groups according to age: younger adult dogs (1~2 years old, 7 animals) and older adult dogs (9~11 years old, 4 animals). Each animal exercised on the treadmill for 25 minutes, twice a week, and for 4 weeks. The exercise intensity was gradually increased by applying four different protocols. Resting HR, HR during exercise, and HR recovery time were determined as HR parameters. Biochemical analysis was performed on blood samples. The independent Student’s t-test and one-way ANOVA were used to analyze the mean difference of each variable. The associations between age and HR parameters were determined using Spearman‘s analysis. [Results] Older adult dogs showed higher HRs during rest and exercise than younger adult dogs. HR recovery time was significantly longer in older adult dogs than in younger adult dogs. A strong positive relationship was observed between beagles’ age and resting HR, HR during exercise, and HR recovery time, respectively. The heart rate response to the treadmill exercise was similar between the 1st week and 4th week in younger and older adult dogs. Exercise significantly reduced the white blood cell level in older adult dogs and increased the alkali phosphatase level in younger adult dogs. [Conclusions] The results of this study demonstrated that short-term treadmill exercise may have a positive effect on the aerobic capacity, inflammation, and bone formation, suggesting that dogs are valuable as aging model in exercise science research.

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