가토에서 상직근 Z-근연절단술 후 절단폭에 따른 근육약화 효과와 근장력의 변화
Muscle Weakening and Change of Tension According to Degree of Superior Rectus Z-Myotomy in Rabbits
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목적: 가토에서 상직근 Z-근연절단술을 절단폭을 달리하여 시행하였을 때 근육약화효과와 근장력의 변화를 알아보았다. 대상과 방법: 가토 15마리(30안)의 상직근을 분리한 후 근육부착부위에서 10 mm 되는 위치에 표식을 한 후 근육부착부위에서 2 mm와8 mm 떨어진 곳에 어긋나게 근연절단술을 각각 시행하였다. 근연절단은 근육폭의 25%를 절단한 군을 1군(10안)으로, 50%는 2군(10안), 75%는 3군(10안)으로 하였으며, 절단술 직후 근육부착부위와 표식자 사이의 근육의 길이변화와 근육을 작용 반대방향으로 당길때 근장력의 변화를 측정하고, 수술 후 4주에 각각 재평가하였다. 결과: 근연절단 직후 표식자의 위치는 모두 후방으로 이동되었고, 1군에서 10.83 ± 0.13 mm, 2군에서 11.02 ± 0.17 mm, 3군에서 12.01± 0.23 mm로 각각 측정되었다. 근장력은 1군은 3.98 ± 0.22 mm, 2군은 3.54 ± 0.18 mm, 3군은 2.87 ± 0.25 mm로 군간 비교에서2군과 3군에서 유의한 감소가 나타났다(p˂0.05). 술후 4주에 표식자의 위치는 1군과 2군, 3군에서 10.55 ± 0.14 mm, 10.85 ± 0.20mm, 11.91 ± 0.14 mm로 나타나 2군과 3군에서 유의한 변화가 있었고(p˂0.05), 근장력도 4.01 ± 0.31 mm, 3.88 ± 0.53 mm, 3.12± 0.42 mm로 2군과 3군에서 유의한 변화가 있었다(p˂0.05). 결론: 상직근의 Z-근연절단술은 근육폭의 75%를 절제하였을 때 현저한 근육약화효과와 근장력의 감소를 볼 수 있었다.
Abstract
Purpose: To identify the muscle weakening effect and the change of muscle tension according to degree of superior rectus Z-myotomy in rabbits. Methods: After dissection of superior rectus in 15 rabbits (30 eyes), marking was done on 10 mm apart from muscle insertion. Then, Z-myotomy was done on 2 mm and 8 mm apart from muscle insertion which are two different positions on apposite sides. 25%, 50% and 75% Z-myotomy were defined as group 1 (10 eyes), group 2 (10 eyes) and group 3 (10eyes). After Z-myotomy, the change of muscle lengthening between muscle insertion and marking, and muscle tension were measured. At 4 weeks after Z-myotomy, all parameters were re-measured. Results: After Z-myotomy all markings moved posteriorly, and showed result as 10.83 ± 0.13 mm in group 1, 11.02 ± 0.17mm in group 2 and 12.01 ± 0.23 mm in group 3 respectively. Muscle tension result showed as 3.98 ± 0.22 mm in group 1,3.54 ± 0.18 mm in group 2 and 2.87 ± 0.25 mm in group 3. In comparison of three groups, group 2 and group 3 showed the significant results (p < 0.05). At 4 weeks after Z-myotomy the markings showed result as 10.55 ± 0.14 mm, 10.85 ± 0.20mm, 11.91 ± 0.14 mm respectively, and in group 2 and group 3 the significant changes were seen (p < 0.05). Muscle tensions were 4.01 ± 0.31 mm, 3.88 ± 0.53 mm, 3.12 ± 0.42 mm respectively. There were significant results in group 2 and group 3 (p < 0.05). Conclusions: 75% Z-myotomy of superior rectus showed significant results in muscle weakening and decreasing muscle tension.
참고문헌 (11)
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