임신성 당뇨 선별 및 진단검사로서의 1단계 검사법과 2단계 검사법에 대한 주산기 예후의 비교
Comparison of Pregnancy Prognosis for Gestational Diabetes Diagnosed by the 1-Step and 2-Step Methods
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Purpose: To compare pregnancy complications between the 2 groups of patients with gestational diabetes mellitus (GDM): those diagnosed by the 1-step method and those diagnosed by the 2-step method. Methods: In this retrospective cohort study, the data from outpatient and hospitalization medical records of 201 patients diagnosed with GDM between 2013 and 2017 were reviewed. We compared the pregnancy complications of these patients based on whether they were diagnosed by the 1-step or 2-step method. SPSS ver. 20.0 was used to analyze the data from the 2 groups. The odds ratio and 95% confidence interval of the pregnancy outcomes were estimated using binary logistic regression analysis. Results: On comparing pregnancy-related complications between the groups, there was no significant difference in the incidence of preeclampsia or delivery by cesarean section (p>0.99 and p=0.50, respectively). In the 1-step and 2-step groups, the prevalence of premature birth was significantly high at 19.7 % and 40.3% (p=0.01), respectively. There were no significant differences between the 2 groups in terms of macrosomia, large for gestational age (LGA), small for gestational age (SGA), low APGAR score, and neonatal hypoglycemia (p>0.99, p>0.26, p>0.62, p>0.57, and p>0.45, respectively). Conclusion: On comparing the 2 groups, we found that the 1-step and 2-step GDM groups had similar risks of pregnancy complications, namely preeclampsia, delivery by cesarean section, macrosomia, LGA, SGA, low APGAR scores, and neonatal hypoglycemia.
Abstract
Purpose: To compare pregnancy complications between the 2 groups of patients with gestational diabetes mellitus (GDM): those diagnosed by the 1-step method and those diagnosed by the 2-step method. Methods: In this retrospective cohort study, the data from outpatient and hospitalization medical records of 201 patients diagnosed with GDM between 2013 and 2017 were reviewed. We compared the pregnancy complications of these patients based on whether they were diagnosed by the 1-step or 2-step method. SPSS ver. 20.0 was used to analyze the data from the 2 groups. The odds ratio and 95% confidence interval of the pregnancy outcomes were estimated using binary logistic regression analysis. Results: On comparing pregnancy-related complications between the groups, there was no significant difference in the incidence of preeclampsia or delivery by cesarean section (p>0.99 and p=0.50, respectively). In the 1-step and 2-step groups, the prevalence of premature birth was significantly high at 19.7 % and 40.3% (p=0.01), respectively. There were no significant differences between the 2 groups in terms of macrosomia, large for gestational age (LGA), small for gestational age (SGA), low APGAR score, and neonatal hypoglycemia (p>0.99, p>0.26, p>0.62, p>0.57, and p>0.45, respectively). Conclusion: On comparing the 2 groups, we found that the 1-step and 2-step GDM groups had similar risks of pregnancy complications, namely preeclampsia, delivery by cesarean section, macrosomia, LGA, SGA, low APGAR scores, and neonatal hypoglycemia.
참고문헌 (17)
- Abebe KZ, "Comparison of two screening strategies for gestational diabetes(GDM2)trial : design and rationale", Contemp Clin Trials, 62, pp.43~49 (2017)
- Benhalima K, "Screening and management of gestational diabetes", Best Pract Res Clin Obstet Gynaecol, 29, pp.339~349 (2015)
- Caissutti C, "Scientific evidence for different options for GDM screening and management : controversies and review of the literature", Biomed Res Int, 2017, pp.2746471~ (2017)
- Caissutti C, "Are women positive for the one step but negative for the two step screening tests for gestational diabetes at higher risk for adverse outcomes", Acta Obstet Gynecol Scand, 97, pp.122~134 (2018)
- Farrar D, "Different strategies for diagnosing gestational diabetes to improve maternal and infant health", Cochrane Database Syst Rev, 8, pp.CD007122~ (2017)
- Ferrara A, "Increasing prevalence of gestational diabetes mellitus : a public health perspective", Diabetes Care, 30(30Suppl 2), pp.S141~S146 (2007)
- 강희선, "임신중당뇨병 임부의 유병률 및 의료이용 추이", 한국모자보건학회지, 14(2), pp.170~180 (2010), 한국모자보건학회[DOI]
- Khalifeh A, "One-step versus two-step diagnostic testing for gestational diabetes : a randomized controlled trial", J Matern Fetal Neonatal Med, 33, pp.612~617 (2020)
- Koo BK, "Prevalence of gestational diabetes mellitus in Korea : a national health insurance database study", PLoS One, 11, pp.e0153107~ (2016)
- Luewan S, "Comparison of the screening tests for gestational diabetes mellitus between"One-Step"and"Two-Step"methods among Thai pregnant women", Obstet Gynecol Int, 2018, pp.1521794~ (2018)
- Meltzer SJ, "Gestational diabetes mellitus screening and diagnosis : a prospective randomised controlled trial comparing costs of one-step and two-step methods", BJOG, 117, pp.407~415 (2010)
- Metzger BE, "International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy", Diabetes Care, 33, pp.676~682 (2010)
- Metzger BE, "Hyperglycemia and adverse pregnancy outcomes", N Engl J Med, 358, pp.1991~2002 (2008)
- Nicolosi BF, "Maternal factors associated with hyperglycemia in pregnancy and perinatal outcomes : a Brazilian reference center cohort study", Diabetol Metab Syndr, 12, pp.49~ (2020)
- Saccone G, "One step versus two step approach for gestational diabetes screening : systematic review and meta-analysis of the randomized trials", J Matern Fetal Neonatal Med, 32, pp.1547~1555 (2019)
- Sacks DA, "Frequency of gestational diabetes mellitus at collaborating centers based on IADPSG consensus panel-recommended criteria : the Hyperglycemia and Adverse Pregnancy Outcome(HAPO)Study", Diabetes Care, 35, pp.526~528 (2012)
- Zhu Y, "Prevalence of gestational deiabetes and risk of progression to type 2 diabetes : a global perspective", Curr Diab Rep, 16, pp.7~ (2016)
