동맥경화 검사의 이해
Interpretation of the Results of Arterial Stiffness Tests
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Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Early detection of subclinical atherosclerosis is important for reduction of cardiovascular risk. However, the current diagnostic strategy, which focuses on traditional risk factors or the use of risk scoring, is unsatisfactory. Arterial walls thicken and stiffen with age, a process known as arteriosclerosis. There is a close interaction between arterial stiffness and atherosclerosis. Increased luminal pressure and shear stress caused by arterial stiffening result in endothelial dysfunction, accelerate the formation of atheromas, and stimulate excessive collagen production and deposition in the arterial wall. Carotid intima-media thickness (CIMT) has been shown to predict cardiovascular risk in many large studies. However, there is controversy regarding the value of CIMT for prediction of cardiovascular risk because of differences in study design, specifically with respect to CIMT measurements. Pulse wave velocity (PWV) is the most widely used measure of arterial stiffness; measurement of PWV is simple, non-invasive, and reproducible. Many clinical studies and meta-analyses have shown that PWV has predictive value in cardiovascular disease beyond traditional risk factors, both in the general population and in patients with various diseases. Brachial pressure has been a poor surrogate for aortic pressure for more than 50 years. However, recent studies have shown a closer relationship between central blood pressure and intermediate cardiovascular phenotypes or cardiovascular target organ damage, compared to the respective relationships with brachial blood pressure. Considering the non-invasiveness and ability to collect multiple types of clinical data, measurement of CIMT, PWV, and central blood pressure may be useful to identify patients at high risk for development of cardiovascular disease.
Abstract
Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Early detection of subclinical atherosclerosis is important for reduction of cardiovascular risk. However, the current diagnostic strategy, which focuses on traditional risk factors or the use of risk scoring, is unsatisfactory. Arterial walls thicken and stiffen with age, a process known as arteriosclerosis. There is a close interaction between arterial stiffness and atherosclerosis. Increased luminal pressure and shear stress caused by arterial stiffening result in endothelial dysfunction, accelerate the formation of atheromas, and stimulate excessive collagen production and deposition in the arterial wall. Carotid intima-media thickness (CIMT) has been shown to predict cardiovascular risk in many large studies. However, there is controversy regarding the value of CIMT for prediction of cardiovascular risk because of differences in study design, specifically with respect to CIMT measurements. Pulse wave velocity (PWV) is the most widely used measure of arterial stiffness; measurement of PWV is simple, non-invasive, and reproducible. Many clinical studies and meta-analyses have shown that PWV has predictive value in cardiovascular disease beyond traditional risk factors, both in the general population and in patients with various diseases. Brachial pressure has been a poor surrogate for aortic pressure for more than 50 years. However, recent studies have shown a closer relationship between central blood pressure and intermediate cardiovascular phenotypes or cardiovascular target organ damage, compared to the respective relationships with brachial blood pressure. Considering the non-invasiveness and ability to collect multiple types of clinical data, measurement of CIMT, PWV, and central blood pressure may be useful to identify patients at high risk for development of cardiovascular disease.
참고문헌 (68)
- Izzo JL Jr, "Arterial stiffness and the systolic hypertension syndrome", Curr Opin Cardiol, 19, pp.341~352 (2004)
- "Global Health Observatory (GHO) data" (2012)[URL]
- Nilsson PM, "Vascular aging : a tale of EVA and ADAM in cardiovascular risk assessment and prevention", Hypertension, 54, pp.3~10 (2009)
- Hennekens CH, "Increasing burden of cardiovascular disease : current knowledge and future directions for research on risk factors", Circulation, 97, pp.1095~1102 (1998)
- Choi EK, "Coronary computed tomography angiography as a screening tool for the detection of occult coronary artery disease in asymptomatic individuals", J Am Coll Cardiol, 52, pp.357~365 (2008)
- Pignoli P, "Intimal plus medial thickness of the arterial wall : a direct measurement with ultrasound imaging", Circulation, 74, pp.1399~1406 (1986)
- O’Leary DH, "Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group", N Engl J Med, 340, pp.14~22 (1999)
- Wikstrand J, "Methodological considerations of ultrasound measurement of carotid artery intima-media thickness and lumen diameter", Clin Physiol Funct Imaging, 27, pp.341~345 (2007)
- Kanters SD, "Reproducibility of in vivo carotid intima-media thickness measurements : a review", Stroke, 28, pp.665~671 (1997)
- Touboul PJ, "Mannheim carotid intima-media thickness consensus (2004-2006). An update on behalf of the Advisory Board of the 3rd and 4th Watching the Risk Symposium, 13th and 15th European Stroke Conferences, Mannheim, Germany, 2004, and Brussels, Belgium, 2006", Cerebrovasc Dis, 23, pp.75~80 (2007)
- Bots ML, "Association between the intima-media thickness of the common carotid and subsequent cardiovascular events in subjects, 55 years and older, in the Rotterdam study(ERGO)", Ned Tijdschr Geneeskd, 142, pp.1100~1103 (1998)
- Chambless LE, "Risk factors for progression of common carotid atherosclerosis : the Atherosclerosis Risk in Communities Study, 1987-1998", Am J Epidemiol, 155, pp.38~47 (2002)
- Lee SK, "The carotid artery intima-media thickness measures with ultrasonography in adult volunteers", Korean Circulation J, 29, pp.1201~1211 (1999)
- 배장호, "대한민국 정상인과 위험인자군의 경동맥 내중막 두께:다기관 역학연구", Korean Circulation Journal, 35(7), pp.513~524 (2005), 대한심장학회
- Salonen JT, "Ultrasonographically assessed carotid morphology and the risk of coronary heart disease", Arterioscler Thromb, 11, pp.1245~1249 (1991)
- Bots ML, "Common carotid intima-media thickness and risk of stroke and myocardial infarction : the Rotterdam Study", Circulation, 96, pp.1432~1437 (1997)
- Rosvall M, "Incident coronary events and case fatality in relation to common carotid intima-media thickness", J Intern Med, 257, pp.430~437 (2005)
- Lorenz MW, "Is carotid intima media thickness useful for individual prediction of cardiovascular risk? Ten-year results from the carotid atherosclerosis progression study(CAPS)", Eur Heart J, 31, pp.2041~2048 (2010)
- Chambless LE, "Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors : the Atherosclerosis Risk in Communities(ARIC)Study, 1987-1993", Am J Epidemiol, 146, pp.483~494 (1997)
- Yeboah J, "Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals", JAMA, 308, pp.788~795 (2012)
- Lorenz MW, "Prediction of clinical cardiovascular events with carotid intima-media thickness : a systematic review and meta-analysis", Circulation, 115, pp.459~467 (2007)
- Den Ruijter HM, "Common carotid intima-media thickness measurements in cardiovascular risk prediction : a meta-analysis", JAMA, 308, pp.796~803 (2012)
- Naqvi TZ, "Carotid intima-media thickness and plaque in cardiovascular risk assessment", JACC Cardiovasc Imaging, 7, pp.1025~1038 (2014)
- Polak JF, "Carotid intima-media thickness score, positive coronary artery calcium score, and incident coronary heart disease : the Multi-Ethnic Study of Atherosclerosis", J Am Heart Assoc, 6, pp.e004612~ (2017)
- Lorenz MW, "Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk-results from the PROG-IMT collaboration", PLoS One, 13, pp.e0191172~ (2018)
- McEniery CM, "An analysis of prospective risk factors for aortic stiffness in men : 20-year follow-up from the Caerphilly prospective study", Hypertension, 56, pp.36~43 (2010)
- Asmar R, "Assessment of arterial distensibility by automatic pulse wave velocity measurement. Validation and clinical application studies", Hypertension, 26, pp.485~490 (1995)
- Van Bortel LM, "Clinical applications of arterial stiffness, task Force III : recommendations for user procedures", Am J Hypertens, 15, pp.445~452 (2002)
- Sugawara J, "Brachial-ankle pulse wave velocity : an index of central arterial stiffness", J Hum Hypertens, 19, pp.401~406 (2005)
- Mancia G, "2007 guidelines for the management of arterial hypertension : the task force for the management of arterial hypertension of the European Society of Hypertension(ESH)and of the European Society of Cardiology(ESC)", Eur Heart J, 28, pp.1462~1536 (2007)
- Reference Values for Arterial Stiffness’ Collaboration, "Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’", Eur Heart J, 31, pp.2338~2350 (2010)
- Hofmann B, "Carotid to femoral pulse wave velocity reflects the extent of coronary artery disease", J Clin Hypertens(Greenwich), 16, pp.629~633 (2014)
- Cainzos-Achirica M, "Brachial-ankle pulse wave velocity is associated with coronary calcium in young and middle-aged asymptomatic adults : the Kangbuk Samsung Health Study", Atherosclerosis, 241, pp.350~356 (2015)
- Williams B, "2018 ESC", ESH Guidelines for the management of arterial hypertension, 2018, pp.39, 3021~3104
- Munakata M, "Brachial-ankle pulse wave velocity in the measurement of arterial stiffness : recent evidence and clinical applications", Curr Hypertens Rev, 10, pp.49~57 (2014)
- Laurent S, "Expert consensus document on arterial stiffness : methodological issues and clinical applications", Eur Heart J, 27, pp.2588~2605 (2006)
- Xiong Z, "Relationship between arterial stiffness assessed by brachial-ankle pulse wave velocity and coronary artery disease severity assessed by the SYNTAX score", J Atheroscler Thromb, 19, pp.970~976 (2012)
- Nam HJ, "Association between brachial-ankle pulse wave velocity and occult coronary artery disease detected by multi-detector computed tomography", Int J Cardiol, 157, pp.227~232 (2012)
- Zhang J, "Arterial stiffness and asymptomatic intracranial large arterial stenosis and calcification in hypertensive Chinese", Am J Hypertens, 24, pp.304~309 (2011)
- Kim YB, "Brachial-ankle pulse wave velocity is associated with both acute and chronic cerebral small vessel disease", Atherosclerosis, 245, pp.54~59 (2016)
- Yokokawa H, "Evaluation of atherosclerosis-associated factors and pulse wave velocity for predicting cerebral infarction : a hospital-based, case-control study in Japan", Intern Med J, 37, pp.161~167 (2007)
- Mattace-Raso FU, "Arterial stiffness and risk of coronary heart disease and stroke : the Rotterdam Study", Circulation, 113, pp.657~663 (2006)
- Willum-Hansen T, "Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population", Circulation, 113, pp.664~670 (2006)
- van Sloten TT, "Carotid stiffness is associated with incident stroke : a systematic review and individual participant data meta-analysis", J Am Coll Cardiol, 66, pp.2116~2125 (2015)
- Vlachopoulos C, "Prediction of cardiovascular events and all-cause mortality with arterial stiffness : a systematic review and meta-analysis", J Am Coll Cardiol, 55, pp.1318~1327 (2010)
- Zhong Q, "Carotid-femoral pulse wave velocity in the prediction of cardiovascular events and mortality : an updated systematic review and meta-analysis", Angiology, 69, pp.617~629 (2018)
- Ben-Shlomo Y, "Aortic pulse wave velocity improves cardiovascular event prediction : an individual participant meta-analysis of prospective observational data from 17, 635 subjects", J Am Coll Cardiol, 63, pp.636~646 (2014)
- Ohkuma T, "Brachial-ankle pulse wave velocity and the risk prediction of cardiovascular disease : an individual participant data meta-analysis", Hypertension, 69, pp.1045~1052 (2017)
- Cavalcante JL, "Aortic stiffness : current understanding and future directions", J Am Coll Cardiol, 57, pp.1511~1522 (2011)
- Roman MJ, "Central pressure more strongly relates to vascular disease and outcome than does brachial pressure : the Strong Heart Study", Hypertension, 50, pp.197~203 (2007)
- Pini R, "Central but not brachial blood pressure predicts cardiovascular events in an unselected geriatric population : the ICARe Dicomano Study", J Am Coll Cardiol, 51, pp.2432~2439 (2008)
- McEniery CM, "Central blood pressure : current evidence and clinical importance", Eur Heart J, 35, pp.1719~1725 (2014)
- Vlachopoulos C, "Prediction of cardiovascular events and all-cause mortality with central haemodynamics : a systematic review and meta-analysis", Eur Heart J, 31, pp.1865~1871 (2010)
- Herbert A, "Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors", Eur Heart J, 35, pp.3122~3133 (2014)
- Williams B, "Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes : principal results of the Conduit Artery Function Evaluation(CAFE)study", Circulation, 113, pp.1213~1225 (2006)
- Wang KL, "Central or peripheral systolic or pulse pressure : which best relates to target organs and future mortality", J Hypertens, 27, pp.461~467 (2009)
- Roman MJ, "Relations of central and brachial blood pressure to left ventricular hypertrophy and geometry : the Strong Heart Study", J Hypertens, 28, pp.384~388 (2010)
- de Luca N1, "Selective reduction of cardiac mass and central blood pressure on low-dose combination perindopril", indapamide in hypertensive subjects, 2004, pp.22, 1623~1630
- Boutouyrie P, "Local pulse pressure and regression of arterial wall hypertrophy during long-term antihypertensive treatment", Circulation, 101, pp.2601~2606 (2000)
- Roman MJ, "High central pulse pressure is independently associated with adverse cardiovascular outcome the strong heart study", J Am Coll Cardiol, 54, pp.1730~1734 (2009)
- Mitchell GF, "Arterial stiffness and cardiovascular events : the Framingham Heart Study", Circulation, 121, pp.505~511 (2010)
- Huang CM, "Central versus ambulatory blood pressure in the prediction of all-cause and cardiovascular mortalities", J Hypertens, 29, pp.454~459 (2011)
- Cooper LL, "Components of hemodynamic load and cardiovascular events : the Framingham Heart Study", Circulation, 131, pp.354~361 (2015)
- Bonithon-Kopp C, "Relation of intima-media thickness to atherosclerotic plaques in carotid arteries. The Vascular Aging (EVA) Study", Arterioscler Thromb Vasc Biol, 16, pp.310~316 (1996)
- O'Leary DH, "Distribution and correlates of sonographically detected carotid artery disease in the Cardiovascular Health Study. The CHS Collaborative Research Group", Stroke, 23, pp.1752~1760 (1992)
- Bots ML, "Common carotid intima-media thickness and lower extremity arterial atherosclerosis. The Rotterdam Study", Arterioscler Thromb, 14, pp.1885~1891 (1994)
- Allan PL, "Relationship between carotid intima-media thickness and symptomatic and asymptomatic peripheral arterial disease. The Edinburgh Artery Study", Stroke, 28, pp.348~353 (1997)
- Salonen JT, "Ultrasound B-mode imaging in observational studies of atherosclerotic progression", Circulation, 87, pp.II56~II65 (1993)