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논문KCI 등재

Individual and collective responsibility to enhance regulatory compliance of the Three Rs

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초록

Investigators planning to use animals in their research and theInstitutional Animal Care and Use Committee (IACUC)members who review the research protocols must takepersonal responsibility for ensuring that they have the skills andknowledge to perform their duties, applying the Three Rsprinciples of Russell and Burch. The two Korean lawsintroduced in 2008 and 2009 regulating animal use forscientific purposes in line with the Three Rs principles havebeen revised a total of 11 times over the last 6 years. Bothregulatory agencies, e.g., the Animal and Plant QuarantineAgency and the Ministry of Food and Drug Safety, provideregular training based on the legal requirements. Based on theamended Animal Welfare Act, the IACUC appointmentframework has been upgraded: appointments are now fortwo-year terms and require a qualified training certificate issuedby the Animal and Plant Quarantine Agency since 2012. Theauthors reviewed the current curricular programs and types oftraining conducted by the two governing agencies throughInternet searches. Our Internet survey results suggest that: a)diversity should be provided in training curricula, based on theroles, backgrounds and needs of the individual trainees; b)proper and continued educational programs should beprovided, based on trainees’ experiences; and c) active encouragementby government authorities can improve the quality oftraining curricula.

Abstract

Investigators planning to use animals in their research and theInstitutional Animal Care and Use Committee (IACUC)members who review the research protocols must takepersonal responsibility for ensuring that they have the skills andknowledge to perform their duties, applying the Three Rsprinciples of Russell and Burch. The two Korean lawsintroduced in 2008 and 2009 regulating animal use forscientific purposes in line with the Three Rs principles havebeen revised a total of 11 times over the last 6 years. Bothregulatory agencies, e.g., the Animal and Plant QuarantineAgency and the Ministry of Food and Drug Safety, provideregular training based on the legal requirements. Based on theamended Animal Welfare Act, the IACUC appointmentframework has been upgraded: appointments are now fortwo-year terms and require a qualified training certificate issuedby the Animal and Plant Quarantine Agency since 2012. Theauthors reviewed the current curricular programs and types oftraining conducted by the two governing agencies throughInternet searches. Our Internet survey results suggest that: a)diversity should be provided in training curricula, based on theroles, backgrounds and needs of the individual trainees; b)proper and continued educational programs should beprovided, based on trainees’ experiences; and c) active encouragementby government authorities can improve the quality oftraining curricula.

참고문헌 (16)

  1. Lee, G. H., "Current status of animal use and alternatives in Korean veterinary medical schools", ATLA, 38, pp.221~230 (2010)
  2. 최병인, "Searching and review on the Three Rs information in Korea: time for quality assessment and continued education", BMB Reports, 46(7), pp.335~337 (2013), 생화학분자생물학회
  3. Franco, N. H., "Scientists and the 3Rs: attitudes to animal use in biomedical research and the effect of mandatory training in laboratory animal science", Lab. Animal, 48, pp.50~60 (2014)
  4. "Korea Ministry of Government Legislation"[URL]
  5. "Animal and Plant Quarantine Agency"[URL]
  6. "Ministry of Food and Drug Safety"[URL]
  7. "Animal Welfare Act"[URL]
  8. "Laboratory Animal Law"[URL]
  9. Anderson, L. C., "Institutional and IACUC Responsibilities for Animal Care and Use Education and Training Programs", ILAR J, 48, pp.90~95 (2007)
  10. Balcombe, J., "Progress in the Reduction, Refinement and Replacement of Animal Experimentation", pp.1343~1350 (2000), Elsevier Science BV
  11. Hart, L. A., "Westport, Connecticut, the United States of America", pp.93~109 (2008), Greenwood Press
  12. Nesdill, D., "Literature search strategies to comply with institutional animal care and use committee review requirements", J. Vet. Med. Educ, 38, pp.150~156 (2011)
  13. Crawford, R. L, "Sourcebook of Models for Biomedical Research", pp.49~54 (2008), Humana Press Inc
  14. "Food and Agriculture Officials Training Institute"[URL]
  15. Hudson-Shore, M., "Searching Effectively for Three Rs information", ATLA, 40, pp.22~23 (2012)
  16. "CITI-KOREA"[URL]

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