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Searching and review on the Three Rs information in Korea: time for quality assessment and continued education

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Scientists planning research that involves the use of animals are required by international and/or national law to examine the possibilities for the implementation of Replacement, Reduction and/or Refinement (the Three Rs principles of Russell and Burch)in experiments for research, testing, and education. There are two Korean laws legislating humane use of animals and ethical review prior to animal experiments. This report reviews current practice of the literature search by the researchers and protocol review by the Institutional Animal Care and Use Committees on the Replacement, Reduction and Refinement alternatives in Korea. The promotion and protection of the laboratory animals are one of the core competencies of investigators exploring the ethical conduct of research and good science.

Abstract

Scientists planning research that involves the use of animals are required by international and/or national law to examine the possibilities for the implementation of Replacement, Reduction and/or Refinement (the Three Rs principles of Russell and Burch)in experiments for research, testing, and education. There are two Korean laws legislating humane use of animals and ethical review prior to animal experiments. This report reviews current practice of the literature search by the researchers and protocol review by the Institutional Animal Care and Use Committees on the Replacement, Reduction and Refinement alternatives in Korea. The promotion and protection of the laboratory animals are one of the core competencies of investigators exploring the ethical conduct of research and good science.

참고문헌 (13)

  1. Smith, A. J, "The use of database, information centres and guidelines when planning research that may involve animals", Animal Welfare, 14, pp.347~359 (2005)
  2. Lee, G. H., "Current status of animal use and alternatives in Korean veterinary medical schools", ATLA, 38, pp.221~230 (2010)
  3. Lee, G. H., "Introduction of the Three Rs alternatives into veterinary education in Korea: assessing attitudes of professors and students", Animal Welfare, 21(Suppl 1), pp.175~ (2011)
  4. Russell, W. M. S., "The principles of humane experimental technique", pp.238~ (1959), Methuen
  5. Nesdill, D., "Literature search strategies to comply with institutional animal care and use committee review requirements", J. Vet. Med. Educ, 38, pp.150~156 (2011)
  6. "Korean Animal Protection Act" (2013)[URL]
  7. "Laboratory Animal Law" (2013)[URL]
  8. Crawford, R. L., "Databases for biomedical animal resources, In Sourcebook of Models for Biomedical Research", pp.49~54 (2008), Humana Press Inc.
  9. Lee, G. H., "Development of the Three Rs platform in Korea: Korea National Information Center for the Three Rs", ALTEX 29, Special Issue (Proceedings of WC8), pp.3~5 (2012)
  10. Van Luijk, J., "Assessing the search for information on Three Rs methods, and their subsequent implementation : A national survey among scientists in The Netherlands", ATLA, 39, pp.429~447 (2011)
  11. Gruber, F. P., "Alternatives to animal experimentation in biomedical education", ALTEX, 21(Suppl 1), pp.33~48 (2004)
  12. Anderson, L. C, "Institutional and IACUC responsibilities for animal care and use education and training programs", ILAR J, 48, pp.90~95 (2007)
  13. Hudson-Shore, M., "Searching effectively for Three Rs information", ATLA, 40, pp.22~23 (2012)

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