청력 소실과 이명, 현훈을 동반한 진성 적혈구증가증 1예
A Case of Polycythemia Vera Accompaning Hearing Loss, Tinnitus and Dizziness
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Polycythemia vera (PV) is a chronic myeloproliferative neoplasm (MPN) which is characterized by proliferation of red blood cells, white blood cells and platelets. PV is associated with the JAK2 V617F mutation. The presenting symptom of PV is variable. Headache, weakness, fatigue, pruritus, dyspepsia, dizziness, visual disturbances may be seen in PV patients. Severe complications such as stroke, acute myocardial infarction and pulmonary embolisms are attributed to a red blood cells and platelets causing hyperviscosity and thrombosis. Even though hearing loss, tinnitus and dizziness are belong to symptoms of PV, they are very rare initial presentation for patients with PV. We report a 49-year-old man with PV, whose first symptoms of PV were hearing loss, tinnitus and dizziness.
Abstract
Polycythemia vera (PV) is a chronic myeloproliferative neoplasm (MPN) which is characterized by proliferation of red blood cells, white blood cells and platelets. PV is associated with the JAK2 V617F mutation. The presenting symptom of PV is variable. Headache, weakness, fatigue, pruritus, dyspepsia, dizziness, visual disturbances may be seen in PV patients. Severe complications such as stroke, acute myocardial infarction and pulmonary embolisms are attributed to a red blood cells and platelets causing hyperviscosity and thrombosis. Even though hearing loss, tinnitus and dizziness are belong to symptoms of PV, they are very rare initial presentation for patients with PV. We report a 49-year-old man with PV, whose first symptoms of PV were hearing loss, tinnitus and dizziness.
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