만성 골수성 백혈병 환자에게서 초기 증상으로서의 돌발성 난청
Sudden Hearing Loss as the Initial Manifestation of Chronic Myeloid Leukemia
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Sudden hearing loss rarely presents as an initial manifestation of a hematologic disorder, althoughit can result from various factors. A 48-year-old male had sudden hearing loss in bothears. The pure tone audiometry and audiometry brainstem response revealed profound hearingloss in both ears. Further examination indicated an elevated leukocyte count, and a temporalbone magnetic resonance image suggested potential bleeding in the cochlear and labyrinthof both ears. Upon consultation with hematologic oncology, chronic myeloid leukemia was diagnosed. Hearing loss in leukemia patients is attributed to leukemic infiltration, hemorrhage,infection, and hyperviscosity. Following treatment using tyrosine kinase inhibitor for chronicmyeloid leukemia, the leukocyte count was normalized. However, on the 90th day of treatment,both profound hearing loss persisted. We suspect that the cause of sudden hearing lossmay be related to hemorrhage in both cochlear and labyrinth. Accurate diagnosis and treatmentare essential for preventing complications.
Abstract
Sudden hearing loss rarely presents as an initial manifestation of a hematologic disorder, althoughit can result from various factors. A 48-year-old male had sudden hearing loss in bothears. The pure tone audiometry and audiometry brainstem response revealed profound hearingloss in both ears. Further examination indicated an elevated leukocyte count, and a temporalbone magnetic resonance image suggested potential bleeding in the cochlear and labyrinthof both ears. Upon consultation with hematologic oncology, chronic myeloid leukemia was diagnosed. Hearing loss in leukemia patients is attributed to leukemic infiltration, hemorrhage,infection, and hyperviscosity. Following treatment using tyrosine kinase inhibitor for chronicmyeloid leukemia, the leukocyte count was normalized. However, on the 90th day of treatment,both profound hearing loss persisted. We suspect that the cause of sudden hearing lossmay be related to hemorrhage in both cochlear and labyrinth. Accurate diagnosis and treatmentare essential for preventing complications.
참고문헌 (17)
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