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음성진전 유무에 따른 내전형 연축성 발성장애의 보툴리눔 독소-A 주입 후 음성 특성 변화 양상

The Aspect of Voice Characteristics Change after Botulinum Toxin-A Injection in Patients with Adductor Spasmodic Dysphonia according to Vocal Tremor

최예린|최홍식|임성은|고혜주
한국음성학회 (The Korean Society of Speech Sciences)|2012.12|말소리와 음성과학 (Phonetics and Speech Sciences)|제4권 제4호|pp. 95-107

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참고문헌

키워드

acoustic analysisaerodynamic analysisadductor spasmodic dysphonia (ADSD)vocal tremorBTX-A injectionvital capacity test
주제분류학제간연구

초록

As BTX-A, which has been known to be the most effective treatment for ADSD, is not effective in treating vocal tremors,voice assessment must be employed to perform differential diagnosis of SD and vocal tremor in an accurate fashion. In this study, the characteristics of vocal changes after botulinum toxin injection were compared by analyzing the voice characteristics resulting from the presence of vocal tremors using objective analysis devices, with the aim of helping to provide prognoses and to determine remedial effects in clinical cases comprising patients with adductor spasmodic dysphonia accompanied by voice tremors. Respiratory function tests, aerodynamic analysis, electroglottography (EGG), acoustic analysis, auditory perception tests,and K-VHI had been conducted at intervals of four, eight, and twelve weeks before and after injection, targeting a group of 17ADSD female patients (a ADSD group of four with vocal tremor and a ADSD group of 13 without voice tremor). For average FVC and FEV1, the T group showed statistically significant low averages compared with the NT group, whereas the T group showed statistically significant high average ATRI compared with the NT group. In addition, the T group showed a statistically significant Fatr, lower than that of the NT group. For the ADSD group of patients with voice tremor, their vocal tremor remained unchanged despite noticeable decrease in wringing voices. In other words, as the vocal tremor and wringing voices are two distinctive features, there is a need for the two features to be targeted separately for differential diagnosis.

Abstract

As BTX-A, which has been known to be the most effective treatment for ADSD, is not effective in treating vocal tremors,voice assessment must be employed to perform differential diagnosis of SD and vocal tremor in an accurate fashion. In this study, the characteristics of vocal changes after botulinum toxin injection were compared by analyzing the voice characteristics resulting from the presence of vocal tremors using objective analysis devices, with the aim of helping to provide prognoses and to determine remedial effects in clinical cases comprising patients with adductor spasmodic dysphonia accompanied by voice tremors. Respiratory function tests, aerodynamic analysis, electroglottography (EGG), acoustic analysis, auditory perception tests,and K-VHI had been conducted at intervals of four, eight, and twelve weeks before and after injection, targeting a group of 17ADSD female patients (a ADSD group of four with vocal tremor and a ADSD group of 13 without voice tremor). For average FVC and FEV1, the T group showed statistically significant low averages compared with the NT group, whereas the T group showed statistically significant high average ATRI compared with the NT group. In addition, the T group showed a statistically significant Fatr, lower than that of the NT group. For the ADSD group of patients with voice tremor, their vocal tremor remained unchanged despite noticeable decrease in wringing voices. In other words, as the vocal tremor and wringing voices are two distinctive features, there is a need for the two features to be targeted separately for differential diagnosis.

참고문헌 (36)

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