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5-Hydroxyindole-3-acetic acid와 5-hydroxytryptophol 을 이용한 혈액 및 뇨에서 음주 여부 확인에 관한연구

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참고문헌

주제분류화학

초록

Abstract

The study was carried out to investigate the ratio of ethanol to n-propanol in blood and urinespecimens, and developed a method for distinguishing ingested ethanol from artifactual ethanol in urine samples.In case of no urinary ethanol was detected, the ratio of ethanol to n-propanol concentration was about 12~20ethanol is from drinking or from microbial fermentation. During the metabolism of ethanol, the levels of themetabolite of serotonin (5-hydroxytryptamine, 5-HT) and 5-hydroxyindole-3-acetic acid (5-HIAA) were decreased,while 5-hydroxytryptophol (5-HTOL) was increased. The levels of 5-HTOL/5-HIAA in urine samples of drinkingsuspects were greater than 1, in that of no drinking suspects were less than 1.

참고문헌 (12)

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