Assessment of Therapeutic Response of Ablated Lesion after Radiofrequency Ablation in Patients with Unresectable Lung Malignancies by Multiphase Contrast-enhanced MRI
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: We evaluated which phase was important to recognize local progression of an ablated zone after RFA on multiphase contrast-enhanced MRI (CE-MRI) in patients with unresectable lung malignancy. Materials and Methods: Twenty patients who had unresectable lung malignancy underwent multiphase CE-MRI examinations immediately after RFA. We evaluated the enhancement patterns of the ablated zone on multiphase CE-MRI: type I, no enhancement of the ablated zone; type II, enhancement of the ablated margin; type III, heterogeneous enhancement of the ablated zone. We evaluated the association enhancement type with local progression of the ablated zone on the follow up CT using Spearman’s ranked test. Results: In complete ablation, the enhancement pattern was types I (11.1%) or II (88.9%). In unsuccessfully treated, type II (57.1%) or III (42.9%) pattern observed in the arterial phase. However, types II (21.4%) and III (78.6%) observed in the venous, and types II (7.1%) and III (92.9%) observed equilibrium phases. Local progression of the ablated zone was associated with the enhancement pattern in equilibrium phases (r=0.8, p < .05). Conclusion: Equilibrium phases on multiphase CE-MRI might play a more important role in evaluating an ablated zone for predicting local recurrence after RFA.
Abstract
Purpose: We evaluated which phase was important to recognize local progression of an ablated zone after RFA on multiphase contrast-enhanced MRI (CE-MRI) in patients with unresectable lung malignancy. Materials and Methods: Twenty patients who had unresectable lung malignancy underwent multiphase CE-MRI examinations immediately after RFA. We evaluated the enhancement patterns of the ablated zone on multiphase CE-MRI: type I, no enhancement of the ablated zone; type II, enhancement of the ablated margin; type III, heterogeneous enhancement of the ablated zone. We evaluated the association enhancement type with local progression of the ablated zone on the follow up CT using Spearman’s ranked test. Results: In complete ablation, the enhancement pattern was types I (11.1%) or II (88.9%). In unsuccessfully treated, type II (57.1%) or III (42.9%) pattern observed in the arterial phase. However, types II (21.4%) and III (78.6%) observed in the venous, and types II (7.1%) and III (92.9%) observed equilibrium phases. Local progression of the ablated zone was associated with the enhancement pattern in equilibrium phases (r=0.8, p < .05). Conclusion: Equilibrium phases on multiphase CE-MRI might play a more important role in evaluating an ablated zone for predicting local recurrence after RFA.
참고문헌 (19)
- Fry WA, "Ten-year survey of lung cancer treatment and survival in hospitals in the United States: a national cancer data base report", Cancer, 86, pp.1867~1876 (1999)
- Hsu CP, "Surgical experience in treating T4 lung cancer: its resectability, morbidity, mortality and prognosis", Eur J Surg Oncol, 22, pp.171~176 (1996)
- Lee JM, "Percutaneous radiofrequency ablation for inoperable non-small cell lung cancer and metastases: preliminary report", Radiology, 230, pp.125~134 (2004)
- Suh RD, "Unresectable pulmonary malignancies: CT-guided percutaneous radiofrequency ablation--preliminary results", Radiology, 229, pp.821~829 (2003)
- Ketchedjian A, "Minimally invasive techniques for managing pulmonary metastases: video-assisted thoracic surgery and radiofrequency ablation", Thorac Surg Clin, 16, pp.157~165 (2006)
- Dupuy DE, "Percutaneous radiofrequency ablation of malignancies in the lung", AJR Am J Roentgenol, 174, pp.57~59 (2000)
- Steinke K, "Percutaneous imaging-guided radiofrequency ablation in patients with colorectal pulmonary metastases: 1-year follow-up", Ann Surg Oncol, 11, pp.207~212 (2004)
- Bojarski JD, "CT imaging findings of pulmonary neoplasmas after treatment with radiofrequency ablation: results in 32 tumors", AJR Am J Roentgenol, 185, pp.466~471 (2005)
- Jin GY, "Primary and secondary lung malignancies treated with percutaneous radiofrequency ablation: evaluation with follow-up helical CT", AJR Am J Roentgenol, 183, pp.1013~1020 (2004)
- Okuma T, "Assessment of early treatment response after CT-guided radiofrequency ablation of unresectable lung tumours by diffusion-weighted MRI: a pilot study", Br J Radiol, 82, pp.989~994 (2009)
- Oyama Y, "Radiofrequency ablated lesion in the normal porcine lung: long-term follow-up with MRI and pathology", Cardiovasc Intervent Radiol, 28, pp.346~353 (2005)
- Rofsky NM, "Abdominal MR imaging with a volumetric interpolated breath-hold examination", Radiology, 212, pp.876~884 (1999)
- Karabulut N, "MR imaging of the chest using a contrast-enhanced breath-hold modified three-dimensional gradient-echo technique: comparison with two-dimensional gradient-echo technique and multidetector CT", AJR Am J Roentgenol, 179, pp.1225~1233 (2002)
- Goldberg SN, "Image-guided tumor ablation: standardization of terminology and reporting criteria", Radiology, 235, pp.728~739 (2005)
- Vogl TJ, "Percutaneous thermoablation of pulmonary metastases. Experience with the application of laser-induced thermotherapy(LITT) and radiofrequency ablation(RFA), and a literature review", Rofo, 176, pp.1658~1666 (2004)
- Liao WJ, "Investigation of short-term therapy results for radiofrequency ablation by positron emission tomography", Di Yi Jun Yi Da Xue Bao, 22, pp.376~377 (2002)
- Miao Y, "Radiofrequency ablation for eradication of pulmonary tumor in rabbits", J Surg Res, 99, pp.265~271 (2001)
- Lencioni R, "Radiofrequency ablation of lung malignancies: where do we stand", Cardiovasc Intervent Radiol, 27, pp.581~590 (2004)
- Smith S, "Imaging appearances following thermal ablation", Clinical Radiology, 63, pp.1~11 (2008)