Recent technical advances in radiofrequency ablations for hepatocellular carcinoma
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Radiofrequency ablation (RFA) has regarded as a curative treatment method for early stage hepatocellular carcinoma (HCC), providing comparable overall survival to surgical resection. However, lack of ideal guiding modality for RFA procedure and higher rate of local tumor progression (LTP) after treatment than surgical resection have been important limitations. To overcome the current limitations of RFA, the fusion imaging between real-time ultrasound and reference computed tomography/magnetic resonance images has been introduced. The fusion imaging could improve the feasibility of RFA for HCC by helping the accurate identification of target HCC, especially for invisible small HCC. In addition, RFA using multiple electrodes with multi-channel generator and various energy delivery modes could improve the therapeutic efficacy, by creating larger ablation volume than RFA using a single electrode. RFA using multiple electrodes can allow no touch ablation technique, which might have a potential to reduce LTP. In this review, these recently introduced ablation techniques will be discussed with the results of both animal and clinical studies.
Abstract
Radiofrequency ablation (RFA) has regarded as a curative treatment method for early stage hepatocellular carcinoma (HCC), providing comparable overall survival to surgical resection. However, lack of ideal guiding modality for RFA procedure and higher rate of local tumor progression (LTP) after treatment than surgical resection have been important limitations. To overcome the current limitations of RFA, the fusion imaging between real-time ultrasound and reference computed tomography/magnetic resonance images has been introduced. The fusion imaging could improve the feasibility of RFA for HCC by helping the accurate identification of target HCC, especially for invisible small HCC. In addition, RFA using multiple electrodes with multi-channel generator and various energy delivery modes could improve the therapeutic efficacy, by creating larger ablation volume than RFA using a single electrode. RFA using multiple electrodes can allow no touch ablation technique, which might have a potential to reduce LTP. In this review, these recently introduced ablation techniques will be discussed with the results of both animal and clinical studies.
참고문헌 (48)
- Ahmed M, "Image-guided tumor ablation: standardization of terminology and reporting criteria--a 10-year update: supplement to the consensus document", J Vasc Interv Radiol, 25, pp.1706~1708 (2014)
- Yu J, "Percutaneous cooledprobe microwave versus radiofrequency ablation in early-stage hepatocellular carcinoma: a phase III randomised controlled trial", Gut, 66, pp.1172~1173 (2017)
- Vietti Violi N, "Efficacy of microwave ablation versus radiofrequency ablation for the treatment of hepatocellular carcinoma in patients with chronic liver disease: a randomised controlled phase 2 trial", Lancet Gastroenterol Hepatol, 3, pp.317~325 (2018)
- N’Kontchou G, "Radiofrequency ablation of hepatocellular carcinoma: long-term results and prognostic factors in 235 Western patients with cirrhosis", Hepatology, 50, pp.1475~1483 (2009)
- Shiina S, "Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors", Am J Gastroenterol, 107, pp.569~577 (2012)
- Kim YS, "Ten-year outcomes of percutaneous radiofrequency ablation as first-line therapy of early hepatocellular carcinoma: analysis of prognostic factors", J Hepatol, 58, pp.89~97 (2013)
- Lee DH, "Radiofrequency ablation of hepatocellular carcinoma as first-line treatment: long-term results and prognostic factors in 162 patients with cirrhosis", Radiology, 270, pp.900~909 (2014)
- Cucchetti A, "Costeffectiveness of hepatic resection versus percutaneous radiofrequency ablation for early hepatocellular carcinoma", J Hepatol, 59, pp.300~307 (2013)
- European Association for the Study of the Liver, "EASL Clinical Practice Guidelines:management of hepatocellular carcinoma", J Hepatol, 69, pp.182~236 (2018)
- 이동호, "Recent Advances in the Image-Guided Tumor Ablation of Liver Malignancies: Radiofrequency Ablation with Multiple Electrodes, Real-Time Multimodality Fusion Imaging, and New Energy Sources", Korean Journal of Radiology, 19(4), pp.545~559 (2018), 대한영상의학회[DOI]
- 이민우, "Fusion imaging of real-time ultrasonography with CT or MRI for hepatic intervention", ULTRASONOGRAPHY, 33(4), pp.227~239 (2014), 대한초음파의학회
- Ahn SJ, "Real-time US-CT", MR fusion imaging for percutaneous radiofrequency ablation of hepatocellular carcinoma, 2017, pp.66, 347~354
- Mulier S, "Electrodes and multiple electrode systems for radiofrequency ablation: a proposal for updated terminology", Eur Radiol, 15, pp.798~808 (2005)
- Brace CL, "Radiofrequency ablation:simultaneous application of multiple electrodes via switching creates larger, more confluent ablations than sequential application in a large animal model", J Vasc Interv Radiol, 20, pp.118~124 (2009)
- 이정, "Percutaneous Radiofrequency Ablation with Multiple Electrodes for Medium-Sized Hepatocellular Carcinomas", Korean Journal of Radiology, 13(1), pp.34~43 (2012), 대한영상의학회
- Chang W, "No-touch radiofrequency ablation using multiple electrodes: An in vivo comparison study of switching monopolar versus switching bipolar modes in porcine livers", PLoS One, 12, pp.e0176350~ (2017)
- Lencioni R, "Early-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous image-guided radiofrequency ablation", Radiology, 234, pp.961~967 (2005)
- Rhim H, "Planning sonography to assess the feasibility of percutaneous radiofrequency ablation of hepatocellular carcinomas", AJR Am J Roentgenol, 190, pp.1324~1330 (2008)
- Lee MW, "Percutaneous sonographically guided radio frequency ablation of hepatocellular carcinoma: causes of mistargeting and factors affecting the feasibility of a second ablation session", J Ultrasound Med, 30, pp.607~615 (2011)
- Maybody M, "Overview of navigation systems in imageguided interventions", Tech Vasc Interv Radiol, 16, pp.136~143 (2013)
- Song KD, "Fusion imaging-guided radiofrequency ablation for hepatocellular carcinomas not visible on conventional ultrasound", AJR Am J Roentgenol, 201, pp.1141~1147 (2013)
- Crocetti L, "Targeting liver lesions for radiofrequency ablation: an experimental feasibility study using a CT-US fusion imaging system", Invest Radiol, 43, pp.33~39 (2008)
- Lee JY, "Clinical value of CT", MRUS fusion imaging for radiofrequency ablation of hepatic nodules, 2012, pp.81, 2281~2289
- Lee MW, "Percutaneous radiofrequency ablation of hepatocellular carcinoma: fusion imaging guidance for management of lesions with poor conspicuity at conventional sonography", AJR Am J Roentgenol, 198, pp.1438~1444 (2012)
- Ewertsen C, "Real-time image fusion involving diagnostic ultrasound", AJR Am J Roentgenol, 200, pp.W249~W255 (2013)
- Lim S, "Mistargeting after fusion imaging-guided percutaneous radiofrequency ablation of hepatocellular carcinomas", J Vasc Interv Radiol, 25, pp.307~314 (2014)
- Goldberg SN, "Radiofrequency tumor ablation: principles and techniques", Eur J Ultrasound, 13, pp.129~147 (2001)
- Dodd GD 3rd, "Radiofrequency thermal ablation: computer analysis of the size of the thermal injury created by overlapping ablations", AJR Am J Roentgenol, 177, pp.777~782 (2001)
- Dupuy DE, "Image-guided radiofrequency tumor ablation: challenges and opportunities--part II", J Vasc Interv Radiol, 12, pp.1135~1148 (2001)
- Chen MH, "Large liver tumors:protocol for radiofrequency ablation and its clinical application in 110 patients--mathematic model, overlapping mode, and electrode placement process", Radiology, 232, pp.260~271 (2004)
- Ni Y, "A review of the general aspects of radiofrequency ablation", Abdom Imaging, 30, pp.381~400 (2005)
- Lee JM, "Switching monopolar radiofrequency ablation technique using multiple, internally cooled electrodes and a multichannel generator: ex vivo and in vivo pilot study", Invest Radiol, 42, pp.163~171 (2007)
- Laeseke PF, "Multiple-electrode radiofrequency ablation of hepatic malignancies: initial clinical experience", AJR Am J Roentgenol, 188, pp.1485~1494 (2007)
- Woo S, "Small- and medium-sized hepatocellular carcinomas: monopolar radiofrequency ablation with a multipleelectrode switching system-mid-term results", Radiology, 268, pp.589~600 (2013)
- Choi JW, "Switching monopolar radiofrequency ablation using a separable cluster electrode in patients with hepatocellular carcinoma: a prospective study", PLoS One, 11, pp.e0161980~ (2016)
- 윤정희, "Dual Switching Monopolar Radiofrequency Ablation Using a Separable Clustered Electrode: Comparison with Consecutive and Switching Monopolar Modes in Ex Vivo Bovine Livers", Korean Journal of Radiology, 14(3), pp.403~411 (2013), 대한영상의학회[DOI]
- 최태원, "Percutaneous Dual-Switching Monopolar Radiofrequency Ablation Using a Separable Clustered Electrode: A Preliminary Study", Korean Journal of Radiology, 18(5), pp.799~808 (2017), 대한영상의학회[DOI]
- 윤정희, "Monopolar Radiofrequency Ablation Using a Dual-Switching System and a Separable Clustered Electrode: Evaluation of the In Vivo Efficiency", Korean Journal of Radiology, 15(2), pp.235~244 (2014), 대한영상의학회[DOI]
- Hocquelet A, "Comparison of no-touch multi-bipolar vs. monopolar radiofrequency ablation for small HCC", J Hepatol, 66, pp.67~74 (2017)
- Seror O, "RE: should we use a monopolar or bipolar mode for performing no-touch radiofrequency ablation of liver tumors? Clinical practice might have already resolved the matter once and for all", Korean J Radiol, 18, pp.749~752 (2017)
- Yoon JH, "Switching bipolar hepatic radiofrequency ablation using internally cooled wet electrodes: comparison with consecutive monopolar and switching monopolar modes", Br J Radiol, 88, pp.20140468~ (2015)
- Espinoza S, "Radiofrequency ablation of needle tract seeding in hepatocellular carcinoma", J Vasc Interv Radiol, 16, pp.743~746 (2005)
- Jaskolka JD, "Needle tract seeding after radiofrequency ablation of hepatic tumors", J Vasc Interv Radiol, 16, pp.485~491 (2005)
- Stigliano R, "Seeding following percutaneous diagnostic and therapeutic approaches for hepatocellular carcinoma. What is the risk and the outcome? Seeding risk for percutaneous approach of HCC", Cancer Treat Rev, 33, pp.437~447 (2007)
- Seror O, "Hepatocellular carcinoma within milan criteria: no-touch multibipolar radiofrequency ablation for treatment-long-term results", Radiology, 280, pp.611~621 (2016)
- Tae-Hyung Kim, "No-Touch Radiofrequency Ablation of VX2 Hepatic Tumors In Vivo in Rabbits: A Proof of Concept Study", Korean Journal of Radiology, 19(6), pp.1099~1109 (2018), 대한영상의학회[DOI]
- Park SJ, "Switching monopolar notouch radiofrequency ablation using octopus electrodes for small hepatocellular carcinoma: a randomized clinical trial", Liver Cancer, 10, pp.72~81 (2021)
- Lee DH, "Outcome of no-touch radiofrequency ablation for small hepatocellular carcinoma: a multicenter clinical trial", Radiology, 301, pp.229~236 (2021)
