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Radiofrequency ablation of very-early-stage hepatocellular carcinoma inconspicuous on fusion imaging with B-mode US: value of fusion imaging with contrast-enhanced US

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Background/Aims: To determine the value of fusion imaging with contrast-enhanced ultrasonography (CEUS) andcomputed tomography (CT)/magnetic resonance (MR) images for percutaneous radiofrequency ablation (RFA) ofvery-early-stage hepatocellular carcinomas (HCCs) that are inconspicuous on fusion imaging with B-mode ultrasound(US) and CT/MR images. Methods: This retrospective study was approved by our institutional review board and the requirement for informedconsent was waived. Fusion imaging with CEUS using Sonazoid contrast agent and CT/MR imaging was performedon HCCs (<2 cm) that were inconspicuous on fusion imaging with B-mode US. We evaluated the number of cases thatbecame conspicuous on fusion imaging with CEUS. Percutaneous RFA was performed under the guidance of fusionimaging with CEUS. Technical success and major complication rates were assessed. Results: In total, 30 patients with 30 HCCs (mean, 1.2 cm; range, 0.6-1.7 cm) were included, among which 25 (83.3%)became conspicuous on fusion imaging with CEUS at the time of the planning US and/or RFA procedure. Of those25 HCCs, RFA was considered feasible for 23 (92.0%), which were thus treated. The technical success and majorcomplication rates were 91.3% (21/23) and 4.3% (1/23), respectively. Conclusions: Fusion imaging with CEUS and CT/MR imaging is highly effective for percutaneous RFA of very-earlystageHCCs inconspicuous on fusion imaging with B-mode US and CT/MR imaging.

Abstract

Background/Aims: To determine the value of fusion imaging with contrast-enhanced ultrasonography (CEUS) andcomputed tomography (CT)/magnetic resonance (MR) images for percutaneous radiofrequency ablation (RFA) ofvery-early-stage hepatocellular carcinomas (HCCs) that are inconspicuous on fusion imaging with B-mode ultrasound(US) and CT/MR images. Methods: This retrospective study was approved by our institutional review board and the requirement for informedconsent was waived. Fusion imaging with CEUS using Sonazoid contrast agent and CT/MR imaging was performedon HCCs (<2 cm) that were inconspicuous on fusion imaging with B-mode US. We evaluated the number of cases thatbecame conspicuous on fusion imaging with CEUS. Percutaneous RFA was performed under the guidance of fusionimaging with CEUS. Technical success and major complication rates were assessed. Results: In total, 30 patients with 30 HCCs (mean, 1.2 cm; range, 0.6-1.7 cm) were included, among which 25 (83.3%)became conspicuous on fusion imaging with CEUS at the time of the planning US and/or RFA procedure. Of those25 HCCs, RFA was considered feasible for 23 (92.0%), which were thus treated. The technical success and majorcomplication rates were 91.3% (21/23) and 4.3% (1/23), respectively. Conclusions: Fusion imaging with CEUS and CT/MR imaging is highly effective for percutaneous RFA of very-earlystageHCCs inconspicuous on fusion imaging with B-mode US and CT/MR imaging.

참고문헌 (24)

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