조혈모세포이식 후 생존기간에 따른 수행능력과 삶의 질
Performance Status and Quality Life of Patients with Hematopoietic Stem Cell Transplantation According to Period of Survival
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Purpose: The purpose of this study was to identify the performance status and quality of life (QOL) of patients after hematopoietic stem cell transplantation (HSCT) according to period of survival. Methods: Participants consists of 83 HSCT patients who were being treated regularly at out-patient clinic in two general hospitals in D city. Data were collected using questionnaires that were modified by Functional Assessment of Cancer Therapy-Bone Marrow Transplabtation (FACT-BMT) scale and Eastern Cooperative Oncology Group (ECOG). Results: The unrelated HSCT group’s survival period was significantly worse than related HSCT group and autologous HSCT group. Performance status of the group with more than 3 years survival was significantly higher than that of the group with less than a year survival. The mean score of total QOL of HSCT patients was 2.69 out of 4. Total QOL was not significantly different among period of survival less than 1 year, 1-3 years, and more than 3 years. But BMT QOL was shown that the group with more than 3 years survival was higher than the groups with less than a year survival. Conclusion: Performance status and BMT QOL of the group with less than 1 year survival was significantly lowered than the groups with more than 3 years survival.
Abstract
Purpose: The purpose of this study was to identify the performance status and quality of life (QOL) of patients after hematopoietic stem cell transplantation (HSCT) according to period of survival. Methods: Participants consists of 83 HSCT patients who were being treated regularly at out-patient clinic in two general hospitals in D city. Data were collected using questionnaires that were modified by Functional Assessment of Cancer Therapy-Bone Marrow Transplabtation (FACT-BMT) scale and Eastern Cooperative Oncology Group (ECOG). Results: The unrelated HSCT group’s survival period was significantly worse than related HSCT group and autologous HSCT group. Performance status of the group with more than 3 years survival was significantly higher than that of the group with less than a year survival. The mean score of total QOL of HSCT patients was 2.69 out of 4. Total QOL was not significantly different among period of survival less than 1 year, 1-3 years, and more than 3 years. But BMT QOL was shown that the group with more than 3 years survival was higher than the groups with less than a year survival. Conclusion: Performance status and BMT QOL of the group with less than 1 year survival was significantly lowered than the groups with more than 3 years survival.
참고문헌 (30)
- 김정아, "혈액질환에서의 새로운 조혈모세포이식 기법", 대한내과학회지, 78(5), pp.552~556 (2010), 대한내과학회
- "Trends in allogeneic transplants" (2010)[URL]
- Lee JW, "The activity of hematopoietic stem cell transplantation in Korea", Bone Marrow Transplant, 42, pp.92~95 (2008)
- Park JG, "Oncology" (2009), Ilchokak
- Zittoun R, "Quality of life in patients with acute myelogenous leukemia in prolonged first complete remission after bone marrow transplantation (allogeneic or autologous) or chemotherapy: a cross-sectional study of the ORTC-GIMEMA AML 8A trial", Bone Marrow Transplant, 20, pp.307~315 (1997)
- Han SH, "The effect of aerobic exercise program on health status and physical fitness in patients after the stem cell transplantation", Korean J Rehabil Nurs, 4, pp.7~19 (2001)
- , Kyungpook National Univ, 2006
- 손수경, "암환자의 피로와 기능상태의 관계*", Asian Oncology Nursing, 7(1), pp.3~13 (2007), 대한종양간호학회
- Hjermstad MJ, "A prospective study of health-related quality of life, fatigue, anxiety and depression 3-5 years after stem cell transplantation", Bone Marrow Transplant, 34, pp.257~266 (2004)
- Bevans MF, "Adjustment, quality of life symptoms (FAQS) in allogeneic hematopoietic stem cell transplantation (HSCT) survivors: A study protocol", Health Qual Life Outcomes, 9, pp.24~32 (2001)
- 송병은, "조혈모세포 이식환자의 삶의 질", Asian Oncology Nursing, 8(1), pp.40~49 (2008), 대한종양간호학회
- , Seoul National Univ, 2001
- , Hanyang Univ, 2004
- Bush NE, "Quality of life 125 adults surviving 6-18 years after bone marrow transplantation", Soc Sci & Med, 40, pp.479~490 (1995)
- Kopp M, "Quality of life in adult hematopoietic cell transplant patients at least 5yr after treatment. a comparison with healthy controls", Eur J Haematol, 74, pp.304~308 (2005)
- Song CW, "Results of IVAM chemotherapy in relapsed or refractory non- Hodgkin’s Lymphoma", Korean J Med, 61, pp.141~150 (2001)
- McGill JS, "Functional status and hope in elderly people with and without cancer", Oncol Nurs Forum, 20, pp.1207~1213 (1993)
- Ferrans CE, "Psychometric assessment of the quality of life index", Res Nurs Health, 15, pp.29~38 (1992)
- McQuellon RP, "Quality of life measurement in bone marrow transplantation: development of the functional assessment of cancer therapy-bone marrow transplantation (FACT-BMT) scale", Bone Marrow Transplant, 19, pp.357~368 (1997)
- "Malignant lymphoma: Cancer stage" (2010)[URL]
- , Keimyung Univ, 2009
- , Yonsei Univ, 2002
- 김은지, "자가 조혈모세포 이식환자와 동종 조혈모세포 이식환자의 삶의 질의 비교", Asian Oncology Nursing, 8(1), pp.50~60 (2008), 대한종양간호학회
- Syrjala KL, "Recovery and long-term function after hematopoietic cell transplantation for leukemia or lymphoma", JAMA, 291, pp.2335~2343 (2004)
- Messerer D, "Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia", Haematologica, 93, pp.826~833 (2008)
- Lee SJ, "Chronic graft-versus-host disease", Bone Marrow Transplant, 9, pp.215~233 (2003)
- González-Vicent M, "Allogeneic hematopoietic transplantation using haploidentical donor vs. unrelated cord blood donor in pediatric patients: a single-center retrospective study", Eur J Haematol, 87, pp.46~53 (2011)
- Lee SJ, "Quality of life associated with acute and chronic graft-versus-host disease", Bone Marrow Transplant, 38, pp.305~310 (2006)
- Fall-Dickson JM, "Oral symptom intensity, health-related quality of life, and correlative salivary cytokines in adult survivors of hematopoietic stem cell transplantation with oral chronic graft-versus-host disease", Biol Blood Marrow Transplant, 16, pp.948~956 (2010)
- Popat U, "Long-term outcome of reduced-intensity allogeneic hematopoietic SCT in patients with AML in CR", Bone Marrow Transplant, 47, pp.212~216 (2012)