자가면역질환인 아토피피부염과 운동에 관한 연구동향
Research Trends on Atopic Dermatitis an Autoimmune Disease and Exercise
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
PURPOSE: Autoimmune diseases attack the organs and tissues of the body because of abnormalities in the immune system, causing health issues such as inflammation and atopic dermatitis. Atopic dermatitis is a chronic inflammatory skin disease with a multifactorial pathogenesis that presents with an itchy, dry dermis. Atopic dermatitis can be alleviated or worsened by environmental factors, and studies have reported that exercise has various effects on atopic dermatitis. METHODS: This review collected and analyzed data on the effects of exercise and atopic dermatitis from previous studies obtained through online databases and search engines, including PubMed, Web of Science, and Google Scholar. RESULTS: Moderate exercise has a positive effect on the health of patients with atopic dermatitis. During moderate- and high-intensity exercise, the thickness of the dermis and epidermis of atopic skin, serum immunoglobulin (Ig)E levels, and cytokine levels decreased. However, conflicting results showed that high-intensity swimming exercises increased the severity of atopic dermatitis. Additionally, patients with atopic dermatitis and lower physical activity levels showed increased disease severity. CONCLUSIONS: These results indicate that several exercises have therapeutic potential against atopic diseases. Further studies are required to investigate the effects of exercise on atopic dermatitis, including the limitations.
Abstract
PURPOSE: Autoimmune diseases attack the organs and tissues of the body because of abnormalities in the immune system, causing health issues such as inflammation and atopic dermatitis. Atopic dermatitis is a chronic inflammatory skin disease with a multifactorial pathogenesis that presents with an itchy, dry dermis. Atopic dermatitis can be alleviated or worsened by environmental factors, and studies have reported that exercise has various effects on atopic dermatitis. METHODS: This review collected and analyzed data on the effects of exercise and atopic dermatitis from previous studies obtained through online databases and search engines, including PubMed, Web of Science, and Google Scholar. RESULTS: Moderate exercise has a positive effect on the health of patients with atopic dermatitis. During moderate- and high-intensity exercise, the thickness of the dermis and epidermis of atopic skin, serum immunoglobulin (Ig)E levels, and cytokine levels decreased. However, conflicting results showed that high-intensity swimming exercises increased the severity of atopic dermatitis. Additionally, patients with atopic dermatitis and lower physical activity levels showed increased disease severity. CONCLUSIONS: These results indicate that several exercises have therapeutic potential against atopic diseases. Further studies are required to investigate the effects of exercise on atopic dermatitis, including the limitations.
참고문헌 (30)
- Langan SM, "Atopic dermatitis", Lancet, 396(10247), pp.345~360 (2020)[DOI]
- Bylund S, "Prevalence and incidence of Atopic dermatitis: a systematic review", Acta Derm Venereol, 100(12), pp.00160~ (2020)[DOI]
- Lee YD, "A Study on the actual use and satisfaction level of moisturizers for atopic dermatitis for children", 12(2), pp.279~293 (2022)
- Li H, "Update on the pathogenesis and therapy of atopic dermatitis", Clin Rev Allergy Immunol, 61(3), pp.324~338 (2021)[DOI]
- Lee HS, "Licoricidin abrogates t-cell activation by modulating PTPN1 activity and attenuates atopic dermatitis in vivo", J Invest Dermatol, 141(10), pp.2490~2498 (2021)[DOI]
- Choi EJ, "Extracts of Grifola frondosa inhibit the MAPK signaling pathways involved in keratinocyte inflammation and ameliorate atopic dermatitis", Nutr Res Pract, 17(6), pp.1056~1069 (2023)[DOI]
- Julius GC, "Challenges and future trends in atopic dermatitis", Int J Mol Sci, 24(14), pp.11380~ (2023)[DOI]
- Choi M, "Factors Affecting the improvement of adult atopic dermatitis in their 20s and 30s : the seventh Korean national health and nutrition examination survey, 2016-2018", Korean J Fam Pract, 10(6), pp.431~435 (2020)[DOI]
- Schwartzman G, "Association of adult atopic dermatitis severity with decreased physical activity : a cross-sectional study", Dermatitis, 34(3), pp.218~223 (2023)[DOI]
- Mitchell EA, "The association between BMI, vigorous physical activity and television viewing and the risk of symptoms of asthma, rhinoconjunctivitis and eczema in children and adolescents : ISAAC phase three", Clin Exp Allergy, 43(1), pp.73~84 (2013)[DOI]
- Kwak YS, "The Scientific Analysis of physical anaphylaxis and FDEIAn", Exerx Sci, 24(3), pp.217~224 (2015)[DOI]
- Acharya D, "Factors associated with atopic dermatitis and allergic rhinitis among residents of Two Municipal Areas in South Korea", Medicina(Kaunas), 55(5), pp.131~ (2019)[DOI]
- Rotter G, "Lifestyle behaviors in patients with atopic dermatitis : results of a cross-sectional study following a randomized controlled trial", Complement Med Res, 29(6), pp.419~428 (2022)[DOI]
- Williams JR, "Factors influencing atopic dermatitis-a questionnaire survey of schoolchildren’s perceptions", Br J Dermatol, 150(6), pp.1154~1161 (2004)[DOI]
- Orita K, "Strong exercise stress exacerbates dermatitis in atopic model mice, NC", Nga mice, while proper exercise reduces it, 2010, pp.19(12), 1067~1072
- Kim J, "Low-intensity tower climbing resistance exercise reduces experimentally induced atopic dermatitis in mice", J Exerc Rehabil, 15(4), pp.518~525 (2019)[DOI]
- Son WK, "Can moderate-intensity aerobic exercise ameliorate atopic dermatitis?", Exp Dermatiol, 29(8), pp.699~702 (2020)[DOI]
- Choi EJ, "High-intensity resistance training suppresses rxacerbation of atopic dermatitis in mice", Exerc Sci, 29(4), pp.443~449 (2020)[DOI]
- Lee E, "Aquatic exercise for improving immune function and mental stress in pre-frailty elderly women", J Women Aging, 33(6), pp.611~619 (2021)[DOI]
- Al-Sahab B, "Epidemiology of eczema among Lebanese adolescents", Int J Public Health, 53(5), pp.260~267 (2008)[DOI]
- Kim SH, "High-intensity swimming exercise increases dust mite extract and 1-Chloro-2, 4-dinitrobenzene-derived atopic dermatitis in BALB", c Mice, 2014, pp.37, 1179~1185
- Koszorú K, "Quality of life in patients with atopic dermatitis", Cutis, 104(3), pp.174~177 (2019)
- O’Connor C, "Pooling the evidence : a review of swimming and atopic dermatitis", Pediatric Dermatology, 40(3), pp.407~412 (2023)[DOI]
- Đurović MR, "Does age influence the quality of life children with atopic dermatitis?", PLoS One, 14(11), pp.0224618~ (2019)[DOI]
- Yand TH, "Adolescents with atopic dermatitis have lower peak exercise load capacity and exercise volume compared with unaffected peers", Int J Environ Res Public Health, 19(16), pp.10285~ (2022)[DOI]
- Kong S, "Associations between stress and physical activity in Korean adolescents with atopic dermatitis based on the 2018-2019Korea youth risk behavior web-based survey", Int J Environ Res Public Health, 17(21), pp.8175~ (2020)[DOI]
- Chan TC, "Impact of atopic dermatitis on work and activity impairment in Taiwan", Acta Derm Venereol, 101(9), pp.00556~ (2021)[DOI]
- Lonne-Rahm SB, "Adult atopic dermatitis patients and physical exercise : a swedish questionnaire study", Acta Derm Venereol, 94(2), pp.185~187 (2014)[DOI]
- Lim MS, "Physical activity, sedentary habits, sleep, and obesity are associated with asthma, allergic rhinitis, and atopic dermatitis in Korean adolescents", Yonsei Med J, 58(5), pp.1040~1046 (2017)[DOI]
- Strom MA, "Associations of physical activity and sedentary behavior with atopic disease in united states children", J Pediatr, 174, pp.247~253 (2016)[DOI]