노인의 만성질환 개수와 우울 증상의 관계에서 근력의 역할
The Role of Muscular Strength on the Relationship between Number of Chronic Diseases and Depressive Symptom in Older Adults
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PURPOSE: The aim of this study was to investigate whether muscular strength modulates the relationship between number of chronic diseases (NCD) and depression in Korean older adults. METHODS: Data from the Living Profiles of Older People Survey including 10,097 Korean older adults aged ≥65 years were used. Depressive symptoms were defined as a score of ≥8 on the self-administered Korean version of the Geriatric Depression Scale. The muscular strength was assessed by self-reported questionnaire. The NCD was defined as the physician diagnosed chronic conditions. RESULTS: The results showed that depressive symptom was more prevalent as NCD increased in both male (OR=2.650, 95%CI: 2.214- 3.172, p<.001) and female (OR=2.261, 95%CI: 1.880-2.720, p<.001). Similarly, depressive symptom appeared increased as muscular strength decreased in both male (OR=2.323, 95%CI: 1.757-3.073, p<.001) and female subjects (OR=2.280, 95%CI: 1.886-2.775, p<.001) even after adjusted for age, BMI, smoking education, marriage. Moderation analysis showed that the effects of NCD on depressive symptom was modulated by muscular strength (β=0.557, 95% CI=.222-0.891, p=.001) even after adjustments for all the covariates. CONCLUSIONS: In this study, the current findings suggested that muscular strength had a beneficial role between NCD and depressive symptoms in Korean older adults.
Abstract
PURPOSE: The aim of this study was to investigate whether muscular strength modulates the relationship between number of chronic diseases (NCD) and depression in Korean older adults. METHODS: Data from the Living Profiles of Older People Survey including 10,097 Korean older adults aged ≥65 years were used. Depressive symptoms were defined as a score of ≥8 on the self-administered Korean version of the Geriatric Depression Scale. The muscular strength was assessed by self-reported questionnaire. The NCD was defined as the physician diagnosed chronic conditions. RESULTS: The results showed that depressive symptom was more prevalent as NCD increased in both male (OR=2.650, 95%CI: 2.214- 3.172, p<.001) and female (OR=2.261, 95%CI: 1.880-2.720, p<.001). Similarly, depressive symptom appeared increased as muscular strength decreased in both male (OR=2.323, 95%CI: 1.757-3.073, p<.001) and female subjects (OR=2.280, 95%CI: 1.886-2.775, p<.001) even after adjusted for age, BMI, smoking education, marriage. Moderation analysis showed that the effects of NCD on depressive symptom was modulated by muscular strength (β=0.557, 95% CI=.222-0.891, p=.001) even after adjustments for all the covariates. CONCLUSIONS: In this study, the current findings suggested that muscular strength had a beneficial role between NCD and depressive symptoms in Korean older adults.
참고문헌 (36)
- Statistics Korea, "2020 elderly population statistics", Statics Korea, ~ (2020)
- Andrew MK, "Social vulnerability, frailty and mortality in elderly people", Plos One, 3(5), pp.e2232~ (2008)
- Chen L, "Correlation of sarcopenia and depressive mood in older community dwellers a cross-sectional observational study in China", BMJ Open, 10(9), pp.e038089~ (2020)
- "Health insurance review and assessment service", ~ (2022)
- Ministry of health and welfare, "2020 Korean Institute for Health and Social Affairs 2020 Elderly Survey", ~ (2020)
- Meltzer H, "Suicide in schizophrenia : risk factors and clozapine treatment", J Clin Psychiatry, 59(3), pp.15~20 (1998)
- Moussavi S, "Depression, chronic diseases, and decrements in health : results from the World Health Surveys", Lancet, 370(9590), pp.851~858 (2007)
- Tchkonia T, "Aging, cell senescence, and chronic disease : emerging therapeutic strategies", JAMA, 320(13), pp.1319~1320 (2018)
- van den Akker M, "Problems in determining occurrence rates of multimorbidity", J Clin Epidemiol, 54(7), pp.675~679 (2001)
- Maier A, "Risk factors and protective factors of depression in older people 65+. A systematic review", PLoS One, 16(5), pp.e0251326~ (2021)
- Katon WJ, "Clinical and health services relationships between major depression, depressive symptoms, and general medical illness", Biol Psychiatry, 54(3), pp.216~226 (2003)
- Kim CH, "The Effect of college students’ physical activity level on depression and personal relationships", Healthcare, 9(5), pp.526~ (2021)
- Liu R, "Association between chronic disease and depression among older adults in China : the moderating role of social participation", Public Health, 221, pp.73~78 (2023)
- Esteban-Cornejo I, "Handgrip strength and all-cause dementia incidence and mortality : findings from the UK Biobank prospective cohort study", J Cachexia Sarcopenia Muscle, 13(3), pp.1514~1525 (2022)
- García-Hermoso A, "Muscular strength as a predictor of all-cause mortality in an apparently healthy population : a systematic review and meta-analysis of data From approximately 2 million men and women", Arch Phys Med Rehabil, 99(10), pp.2100~2113 (2018)
- Gariballa S, "Association between muscle function, cognitive state, depression symptoms and quality of life of older people : evidence from clinical practice", Aging Clin Exp Res, 30, pp.351~357 (2018)
- Heo JE, "Association between appendicular skeletal muscle mass and depressive symptoms : review of the cardiovascular nd metabolic diseases etiology research center cohort", J Effect Disord, 238, pp.8~15 (2018)
- Kim NH, "Depression is associated with sarcopenia, not central obesity, in elderly Korean men", J Am Geriatr Soc, 59(11), pp.2062~2068 (2011)
- Wang Y, "Association of grip strength and comorbidities with all-cause mortality in the older hypertensive adults", Front Public Health, 11, pp.1162425~ (2023)
- Kekalainen T, "Effects of a 9-month resistance training intervention on quality of life, sense of coherence, and depressive symptoms in older adults : randomized controlled trial", Qual Life Res, 27, pp.455~465 (2018)
- Oliveria PFA, "Resistance training improves isokinetic strength nd metabolic syndromerelated phenotypes in posmenopausal women", Clin Intery Aging, 7, pp.1299~1304 (2015)
- Yesavage JA, "Geriatric depression scale", Psychopharmacol Bull, 24(4), pp.709~711 (1988)
- Jiang CH, "Relationships between chronic diseases and depression among middle-aged and elderly people in China : a prospective study from CHARLS", Curr Med Sci, 40(5), pp.858~870 (2020)
- Li D, "The association between chronic disease and depression in middle-aged and elderly people : the moderating effect of health insurance and health service quality", Front Public Health, 11, pp.935969~ (2023)
- Feng MY, "Influence of chronic diseases on the occurrence of depression: a 13-year follow-up study from the Survey of Health, Ageing and Retirement in Europe", Psychiatry Res, pp.115268~ (2023)
- Smith L, "Physical multimorbidity and depression : a mediation analysis of influential factors among 34, 129 adults aged ≥50 years from low-and middle-income countries", Depress Anxiety, 39(5), pp.376~386 (2022)
- Zasadzka E, "Correlation between handgrip strength and depression in older adults—a systematic review and a meta-analysis", Int J Environ Res Public Health, 18(9), pp.4823~ (2021)
- Cabanas-Sánchez V, "Muscle strength and incidence of depression and anxiety : findings from the UK biobank prospective cohort study", J Cachexia Sarcopenia Muscle, 13(4), pp.1983~1994 (2022)
- Zakharova A, "Association between sarcopenia and depressive symptoms in community-dwelling people aged 40 years and older", Tohoku J Exp Med, 257(2), pp.117~125 (2022)
- Liang Y, "Sport and recreational physical activities attenuate the predictive association of multimorbidity with increased geriatric depressive symptoms : a 14-year follow-up study of community-dwelling older adults", J Aging Phys Act, 30(2), pp.252~260 (2021)
- Kong JY, "Relationship between physical activity and depressive symptoms in older Korean adults : moderation analysis of muscular strength", BMC Geriatrics, 22(1), pp.884~ (2022)
- Lee JM, "The relationship between muscular strength and depression in older adults with chronic disease comorbidity", Int J Environ Res Public Health, 17(18), pp.6830~ (2020)
- Son HJ, "Effect of resistance exercise training on metabolic syndrome and depression in elderly women", Journal of Sport and Leisure Studies, 42(2), pp.947~955 (2010)
- Liu Cj, "Systematic review of functional training on muscle strength, physical functioning, and activities of daily living in older adults", Eur Rev Aging Phys Act, 11, pp.95~106 (2014)
- Kohler CA, "Peripheral cytokine and chemokine alterations in depression : a metaanalysis of 82 studies", Acta Psychiatr Scand, 135(5), pp.373~387 (2017)
- Soysal P, "Relationship between depression and frailty in older adults : a systematic review and meta-analysis", Ageing Res Rev, 36, pp.78~87 (2017)
