히알루론 산을 이용한 비수술적 눈꺼풀 위치 이상의 치료효과
Nonsurgical Treatment of Abnormal Eyelid Position Using Hyaluronic Acid Gel
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
목적: 눈꺼풀위치이상환자에서 히알루론 산 젤 주사 후 효과에 대하여 알아보고자 하였다. 대상과 방법: 본원 안과를 내원하여 히알루론 산 젤 주사술을 받은 토안 10안, 눈꺼풀 뒤당김 18안, 눈꺼풀 겉말림 20안이 대상이었다. 평균 나이는 50±17.8세, 평균 관찰 기간은 11.0±2.4개월이며, 주사 전과 직후 1개월, 4개월, 최종 관찰 시 사진을 Image J Program을 이용하여 MRD1 (marginal reflex distance 1), MRD2 (marginal reflex distance 2)값을 측정하여 분석하였다. 눈꺼풀 겉말림은 술자 평가 및 환자 만족도를 등급화하여 평가하였다. 결과: 토안 10안에서 1.9±1.2 mm가 개선되었고 눈꺼풀 뒤당김 18안에서 1.3±0.9 mm 개선되었다. 눈꺼풀 겉말림 23안 모두 교정되었고 17안에서는 완전교정을 보였다. 평균 주사 횟수는 1.1회, 평균 용량은 0.4±0.1 cc였다. 모든 환자들에서 부종, 멍 외 합병증은 관찰되지 않았다. 결론: 히알루론 산 젤 주사법은 눈꺼풀 위치 이상에서 안전하며 효과가 좋은 비수술적인 방법으로 추후 장기적 경과 관찰이 필요할 것으로 생각한다.
Abstract
Purpose: The present study investigated the outcomes of nonsurgical treatment of abnormal eyelid position using hyaluronic acid gel. Methods: Abnormal eyelid position including 18 eyes with lid retraction, 10 eyes with lagophthalmos, and 18 eyes with ectropion were treated with hyaluronic acid gel. The mean age was 50±17.8 years and the mean observation period was 11±2.4 months. The photographs of patients were taken before injection, 1 month, 4 months, and at the last follow-up after injection. The marginal reflex distance 1 (MRD1) and marginal reflex distance 2 (MRD2) of patients were measured and analyzed by the Image J Program. The severity of ectropion was graded by a scoring system. Results: Ten eyes with lagopthalmos improved 1.9±1.2 mm after injection. The 16 eyes with lid retraction improved 1.3±0.9 mm. Twenty-three eyes with ectropion improved and 17 eyes (81%) were completely corrected. The average frequency of injection was 1.1 and the average dose of injection was 0.4±0.12 cc. No significant complications were observed in any patient. Conclusions: Hyaluronic acid gel injections can be used safely and effectively as a nonsurgical treatment for patients with abnormal eyelid position without any significant complications.
참고문헌 (26)
- Morley AM, "Use of hyaluronic acid gel for upper eyelid filling and contouring", Ophthal Plast Reconstr Surg, 25, pp.440~444 (2009)
- Donath AS, "Volme loss versus gravity: new concepts in facial aging", Curr Opin Otolaryngol Head Neck Surg, 15, pp.238~243 (2007)
- Colemans SR, "The anatomy of the aging face: volume loss and changes in 3-dimensional topography", Aesthet Surg J, 26(1S), pp.4~9 (2006)
- Zimbler MS, "Anatomy and pathophysiology of facial aging", Facial Plast Surg Clin North Am, 9, pp.179~187 (2001)
- Lambros V, "Volumizing the brow with hyaluronic acid fillers", Aesthet Surg J, 29, pp.174~179 (2009)
- John HE, "Perspectives in the selection of hyaluronic acid fillers for facial wrinkles and aging skin", Patient Prefer Adherence, 3, pp.225~230 (2009)
- Goldberg RA, "Filling the periorbital hollows with hyaluronic acid gel: initial experience with 244 injections", Ophthal Plast Reconstr Surg, 22, pp.335~341 (2006)
- Seiff SR., "The fat pearl graft in ophthalmic plastic surgery: everyone wants to be a donor!", Orbit, 21, pp.105~109 (2002)
- Ciuci PM, "Rejuvenation of the periorbital complex with autologous fat transfer: current therapy", J Oral Maxillofac Surg, 66, pp.1686~1693 (2008)
- Flowers RS, "Tear trough implants for correction of tear trough deformity", Clin Plast Surg, 20, pp.403~415 (1993)
- Gold MH, "Use of hyaluronic acid fillers for the treatment of the aging face", Clin Interv Aging, 2, pp.369~376 (2007)
- DeLorenzi C, "A multicenter study of the efficacy and safety of subcutaneous nonanimal stabilized hyaluronic acid in aesthetic facial contouring: interim report", Dermatol Surg, 32, pp.205~211 (2006)
- Fezza JP, "Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler", Plast Reconstr Surg, 121, pp.1009~1014 (2008)
- Kane MA., "Treatment of tear trough deformity and lower lid bowing with injectable hyaluronic acid", Aesthetic Plast Surg, 29, pp.363~367 (2005)
- Steinsapir KD, "Deep-fill hyaluronic acid for the temporary treatment of the naso-jugal groove: a report of 303 consecutive treatments", Ophthal Plast Reconstr Surg, 22, pp.344~348 (2006)
- Ross JJ, "Orbitofacial rejuvenation of temporal hollowing with perlane injectable filler", Aesthet Surg J, 30, pp.428~433 (2010)
- Goldberg RA, "Treatment of lower eyelid retraction by expansion of the lower eyelid with hyaluronic acid gel", Ophthal Plast Reconstru Surg, 23, pp.343~348 (2007)
- Zamani M, "Functional use of hyaluronic acid gel in lower eyelid retraction", Arch Ophthalmol, 126, pp.1157~1159 (2008)
- Taban M, "Nonsurgical management of congenital eyelid malpositions using hyaluronic acid gel", Ophthal Plast Reconstr Surg, 25, pp.259~263 (2009)
- Kornstein AN, "Soft-tissue reconstruction of the brow with restylane", Plast Reconstr Surg, 116, pp.2017~2020 (2005)
- Airan LE, "Nonsurgical lower eyelid lift", Plast Reconstr Surg, 116, pp.1785~1792 (2005)
- Biesman B, "Soft tissue augmentation using restylane", Facial Plast Surg, 20, pp.171~177 (2004)
- Lowe NJ, "Adverse reactions to dermal fillers: review", Dermatol Surg, 31, pp.1616~1625 (2005)
- Friedman PM, "Safety data of injectable non animal stabilized hyaluronic acid gel for soft tissue Dugmentation", Dermatol Surg, 28, pp.491~494 (2002)
- Lowe NJ, "Hyaluronic acid skin fillers: adverse reactions and skin testing", J Am Acad Dermatol, 45, pp.930~933 (2001)
- Schanz S, "Arterial embolization caused by injection of hyaluronic acid (Restylane)", Br J Dermatol, 146, pp.928~929 (2002)