프로폴리스를 혼합한 리도카글의 항균 효과 평가
Evaluation of the Antibacterial Effect of Mixed Lidocagle and Propolis
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
.
Abstract
Objectives: This study attempted to verify the antibacterial effect of a lidocagle solution mixed with propolis, at different concentrations, against S. mutans, S. salivarius, and S. mitis. Methods: The disk diffusion method, bacterial activity test, and colony formation evaluation assay were performed to evaluate the antibacterial activity of the solutions. Collected data were analyzed by one-way ANOVA and Tukey's post hoc analyses in SPSS 21.0 ver. (SPSS Inc., Chicago, IL, USA); statistical significance was set at 0.05. Results: In the disc diffusion assay, the diameter of the inhibition zone decreased in media containing Lidocagle and propolis at a high concentration (30 vol%). In contrast, in the bacterial activity evaluation test, bacterial activity increased in media containing propolis an high Lidocagle solution concentrations (except for that at 10% vol). In the colony formation evaluation test, the highest number of colonies was formed in media with propolis and a low concentration of the Lidocagle solution (p<0.05). Conclusions: The results suggest that the antibacterial effect depends on the Lidocagle:propoli ratio in the medium. Results also showed that 10%, 20%, and 30% Lidocagle solution volume mixes had partial antibacterial effect against S. mutans, S. salivarius, and S. mitis.
참고문헌 (20)
- 강윤주, "스켈링 시 구강마취액(해피카인)의 통증완화 정도", 한국치위생학회지, 12(3), pp.495~501 (2012), 한국치위생학회[DOI]
- The Korea Society of Anesthesiologists, "Anesthesiology and pain medicine", pp.193~210 (2022), Ryo Moon Gak
- Korea Dental Society of Anesthesiology, "Dental anesthesiology", pp.77~ (2005), OON-JA
- Yoo HJ, "Experimenton anti-bacterial effect of propolis-containing tooth paste against oral bacteria", master, pp.2011
- 김나래, "여드름 유발균, Propionibacterium acnes에 대한 프로폴리스의 항균 활성에 대한 연구", 한국식품영양과학회지, 49(6), pp.586~591 (2020), 한국식품영양과학회[DOI]
- 이호재, "프로폴리스 용매별 추출물의 생리활성", 한국식품영양과학회지, 34(1), pp.1~7 (2005), 한국식품영양과학회
- 임윤경, "Antimicrobial effect of Australia propolis on cariogenic and periodontopathic bacteria", International Journal of Oral Biology, 44(4), pp.191~194 (2019), 대한구강생물학회
- 정일윤, "프로폴리스에서 분리한 플라보노이드 화합물의 항산화 활성 및 방사선 방어효과", 한국식품영양과학회지, 34(2), pp.162~166 (2005), 한국식품영양과학회
- 최우양, "프로폴리스함유 천연구강청결제의 구강환경변화에 대한 임상적 연구", 한국치위생학회지, 15(2), pp.319~324 (2015), 한국치위생학회[DOI]
- Ro SB, "Evalution of the cytotoxicity of propolis on the human gingival fibroblast and periodontal ligament fibroblast cells", Kor J Dent Mater, 35(spec), pp.37~38 (2008)
- 박헌국, "수용성 프로폴리스의 항균성", 한국식품영양학회지, 21(1), pp.15~21 (2008), 한국식품영양학회
- 권영선, "수종의 치주질환 원인균에 대한 프로폴리스의 항균 효과", 대한치과재료학회지, 33(4), pp.395~405 (2006), 대한치과재료학회
- Kim SI, "Anti-bacterial effect of water-soluble propolis on oral pathogen", doctor, pp.2008
- M. L. Bruschi, "Preparation and Antimicrobial Activityof Gelatin Microparticles Containing Propolis Against Oral Pathogens", Drug Development and Industrial Pharmacy, 32(2), pp.229~238 (2006), Informa UK Limited[DOI]
- 노지연, "Antimicrobial Activity of Korean Propolis Extracts on Oral Pathogenic Microorganisms", 치위생과학회지, 18(1), pp.18~23 (2018), 한국치위생과학회[DOI]
- Park SO, "The clinical effect with the use of gel anesthesia within gingival sulcus during scaling", master, Department of Dental Hygiene, pp.2017
- 이영화, "혈액투석환자의 동정맥루 천자 시 통증과 불안완화를 위한 2% 리도카인 피내주사와 10% 리도카인 분무 효과 비교", 임상간호연구, 13(2), pp.169~177 (2007), 병원간호사회
- Fatih Özan, "Effect of Mouthrinse Containing Propolis on Oral Microorganisms and Human Gingival Fibroblasts", European Journal of Dentistry, 01(04), pp.195~201 (2007), Georg Thieme Verlag KG[DOI]
- 김상아, "프로폴리스의 구강구취균에 대한 항균성", 한국식품과학회지, 45(3), pp.370~375 (2013), 한국식품과학회[DOI]
- Karina Basso Santiago, "Microbiological control and antibacterial action of a propolis-containing mouthwash and control of dental plaque in humans", Natural Product Research, 32(12), pp.1441~1445 (2017), Informa UK Limited[DOI]