12주간의 복합훈련과 훈련중지가 지적장애인의 염증인자에 미치는 영향
The Effects of 12-weeks Training and Detraining with Acute Exercise on Blood Inflammatory Factors with Individuals with Intellectual Disability
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본 연구의 목적은 장기간의 훈련과 훈련의 중지가 일회성운동과 회복에 따라(회복 24시간) 염증인자(TNF-α,IL-6, CRP, WBC)에 어떠한 영향을 미치는지 규명하기 위한 것이다. 총 24명의 지적장애인을 실험집단(n=12)과대조집단(n=12)으로 나누어 매회 65-75분씩, 주당 4회씩 12주간의 훈련을 수행하였다. 대조집단은 운동을 수행하지 않았다. 훈련은 트레드밀 달리기 15-20분, 저항운동 30-35분, 준비운동과 정리운동 각각 10분으로 구성하였다. 훈련 후 2주간 그 훈련을 중지하였다. 일회성운동은 최대심박수의 70-80% 범위에서 30분간 수행하였으며각 처치마다(훈련 전, 훈련 후, 훈련중지 후) 안정 시, 운동직후(30분), 회복 24시에 채혈을 하였다. 분석을 위한통계는 SPSS 통계프로그램을 이용하여 삼원변량분석을 적용하였다. 먼저 훈련 전 일회성운동에 따른 변화를 살펴보면 주효과 검증결과 TNF-α를 제외하고 IL-6, CRP 모두 안정 시에 비하여 운동직후와 회복기에 유의하게증가하였다. 훈련에 따른 변화에서는 안정 시의 경우 유의한 변화는 없었지만 운동직후와 회복기의 경우 훈련전에 비하여 CRP의 유의한 감소가 나타났다. 2주간 훈련중지에 따른 변화에서는 안정 시의 경우 IL-6와 CRP가훈련 후에 비하여 유의하게 감소하였다. 운동직후와 회복에 따른 변화에서는 훈련 후 감소되었던 운동직후와회복기의 CRP가 훈련중지 후 훈련 전 운동직후와 회복기 수준으로 돌아갔다. 결론적으로 장기간의 훈련은 염증인자를 억제키지만 훈련의 중지는 이러한 훈련에 따른 효과를 소멸되는 것으로 나타났다.
Abstract
The purpose of this study was to investigate the effect of 12-week exercise training and then 2-weeks detraining on blood inflammatory factors (TNF-α, IL-6, CRP, WBC). Twenty-four individual with intellectual disability participated in this study and were divided into experimental(n=12) and the control group (n=12). The experimental group performed a 12-weeks exercise training and then stopped exercise training for two weeks whereas the control group continued their ordinary life. Exercise training composed of aerobic exercise (15-20minute treadmill) and weight training (25-30 minutes). Blood sample extracted pre and immediately after exercise and recovery period (24hour later). Blood IL-6 and CRP increased significantly immediately after exercise and recovery period. The increased CRP was lower in training treatment than control group. Blood WBC concentration increased significantly immediately after exercise and decreased recovery period but did not return to the base line levels. In conclusion acute exercise resulted in increased inflammation response and 12-weeks training reduced such exercise induced inflammation during exercise and recovery period. But detraining invalidated chronic exercise induced anti-inflammatory effects. Further study was needed to elucidate the exact mechanism with exercise and detraining related to the degree of detraining period.
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