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근시환자에서 스펙트럼영역 빛간섭단층촬영기를 이용한 굴절력 및 안축장에 따른 맥락막두께의 변화

Choroidal Thickness Changes According to the Refractive Errors and Axial Length in Korean Myopia Patients

김지현|이정호|이규원|김은주|구성현
대한안과학회 (The Korean Ophthalmological Society)|2012.12|대한안과학회지 (Journal of The Korean Ophthalmological Society)|제53권 제12호|pp. 1814-1822

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참고문헌

키워드

SexAxial lengthChoroidal thicknessSpherical equivalentSpectral-domain OCT
주제분류안과학

초록

목적: 한국인의 근시 환자에서 Enhanced depth imaging (EDI)로 측정한 맥락막두께와 굴절력 및 안축장에 따른 변화를 알아보고자하였다. 대상과 방법: 만 19세에서 39세 사이의 근시환자 90명 90안을 대상으로 스펙트럼영역 빛간섭단층촬영기를 이용한 EDI방법으로 맥락막영상을 얻었으며 조절마비굴절검사로 구면렌즈대응치를, IOL masterⓇ로 안축장을 측정하여 중심와아래 맥락막두께와 상관관계를 조사하였다. 결과: 평균 나이는 25.44세, 평균 구면렌즈대응치는 -5.06 디옵터(D), 평균 안축장은 25.70 mm, 평균 중심와아래 맥락막두께는 281.47 μm였다. 다중회귀분석모형에서 맥락막두께는 나이에 따른 유의한 차이는 없었으며, 구면렌즈대응치가 -1D 증가할수록 평균 13.58 μm 감소하였으며, 안축장이 1 mm 증가할수록 평균 33.99 μm 감소하였고, 남성에서 안축장, 굴절력을 보정하였을 때 59.82 μm 두껍게측정되었다(p˂0.001). 결론: 근시를 가진 젊은 한국인에서 맥락막의 두께는 굴절력 및 안축장과 유의한 상관관계가 있으며 이를 보정한 경우 남성에서 여성보다 맥락막두께가 더 두껍게 측정되었다.

Abstract

Purpose: To investigate the choroidal thickness changes with the Enhanced Depth Imaging (EDI) technique according to refractive errors and axial length in Korean myopia patients. Methods: A total of 90 eyes from 90 patients with myopia (between the ages of 19 and 39 years) underwent spectral-domain optical coherence tomography (SD-OCT)-EDI evaluations. Spherical equivalent was measured by cycloplegic refraction and axial length was obtained by IOL master®. The subfoveal choroidal thickness was analyzed according to age,sex, axial length and spherical equivalent by linear correlations. Results: The average age of all subjects was 25.44 years, mean spherical equivalent was -5.06 diopter (D), mean axial length was 25.70 mm, and mean choroidal thickness was 281.47 μm. In a multiple regression model, the patients’ age had no statistical effect on subfoveal choroidal thickness. Subfoveal choroidal thickness decreased by 13.58 μm per -1D increase in refractive errors and by 33.99 μm per 1 mm increase in axial length when adjusted for sex and age. In addition,subfoveal choroidal thickness was 59.82 μm thicker in men than in women when adjusted for axial length and spherical equivalent (p < 0.001). Conclusions: Among young Korean myopia patients, subfoveal choroidal thickness was significantly related with refractive errors and axial length. Moreover, choroidal thickness was thicker in men than women when adjusted for refractive errors and axial length.

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