근시안에서 스펙트럼 영역 빛간섭단층촬영으로 측정한 맥락막 두께와 굴절력 및 안축장과의 관계
The Relationship among Refractive Power, Axial Length and Choroidal Thickness Measured by SD-OCT in Myopia
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목적: 정상 근시안에서 스펙트럼 영역 빛간섭단층촬영기를 사용하여 맥락막 두께를 측정하고, 안축장 길이 및 굴절력과의 관계를 알아보고자 하였다. 대상과 방법: 건강한 정상 근시 80안을 대상으로 하였다. 굴절력을 측정하여 -6.0 미만과 이상 군으로 나누었고 안축장 길이를 측정하여 25 mm 이상과 미만 군으로 나누었다. 모든 대상자는 3D OCT 2000 (Topcon Corp., Tokyo, Japan)를 이용하여 중심와 및 중심와로부터 각각 1500 μm 떨어진 비측, 이측, 상측, 하측 부위의 맥락막 두께를 측정하였고, 굴절력 및 안축장 길이에 따라 상관관계를비교하였다. 결과: 굴절력에 따른 맥락막 두께는 모든 측정 부위에서 -6.0D 미만과 이상 군 사이에 통계적으로 유의한 차이가 있었다(p＜0.001). 안축장 길이에 따른 맥락막 두께는 모든 측정 부위에서 25 mm 이상과 미만 군 사이에 통계적으로 유의한 차이가 있었다(p＜0.05). 결론: 맥락막 두께는 굴절력 및 안축장 길이와 유의한 상관관계가 있으며, 병적 근시가 없는 정상안에서 고도 근시는 경도 및 중등도근시에 비하여 유의한 맥락막 두께의 감소를 유발할 수 있다.
Abstract
Purpose: To measure choroidal thickness in healthy myopic eyes and to evaluate the relationship among choroidal thickness and refractive power and axial length. Methods: Eighty healthy myopic eyes were evaluated in the present study. The refractive power was measured using an automatic refractor and the axial length using A-scan. The subjects were divided into two groups based on refractive power (≥-6.0 D and <-6.0 D) and axial length (≥25 mm and <25 mm). The choroidal thickness was measured using spectral domain (SD) optical coherence tomography (3-dimensional [3D] OCT-2000, Software Version 6.01; Topcon Corp., Tokyo,Japan), and the statistical relationship between the two groups was analyzed. Results: A statistically significant difference was found in choroidal thickness according to refractive power and axial length between the two groups (p < 0.001 and p < 0.05, respectively). Conclusions: Refractive power and axial length had a significant relation to choroidal thickness measured by OCT. When excluding eyes with pathologic myopia, high myopia in healthy eyes may cause choroidal thinning.
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