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가성층판황반원공형 망막전막에서 내경계막 제거의 효과

The Effect of Internal Limiting Membrane Peeling in Epiretinal Membrane Including Pseudolamellar Macular Hole

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목적: 가성층판황반원공형 망막전막 환자에서 망막전막제거술과 동시에 내경계막제거술을 시행한 경우의 시력예후를 알아보고자 하였다. 대상과 방법: 가성층판황반원공형 망막전막으로 진단받은 27안 중에서 유리체절제술 및 가스충전술을 시행하여 술 후 7일간 안면하체위를 하였고, 14안은 망막전막제거술만, 13안은 내경계막제거술도 동시에 시행하였다. 내경계막제거에 따라 두군으로 나누어 술전과술후 12개월 최대교정시력과 빛간섭단층촬영 소견을 후향적으로 조사하여 비교하였다. 결과: 해부학적 폐쇄는 망막전막제거술만 시행한 경우 14안 중 11안(78.6%), 내경계막제거술도 시행한 경우 13안 중 12안(92.3%)으로높은 성공률을 보였다. 망막전막제거술만 시행한 경우 수술 전, 후 시력이 0.41 ± 0.31 (logMAR)에서 0.33 ± 0.21로 호전되었으나통계학적으로 유의하지 않았고, 내경계막제거술을 시행한 경우 0.46 ± 0.41에서 0.28 ± 0.25로 유의한 결과를 보였다(p=0.001). 결론: 가성층판황반원공형 망막전막에서 유리체절제술 및 가스충전술 시행시 망막전막제거술과 동시에 내경계막제거술을 시행한 경우 유의한 시력호전을 보이며 해부학적 및 기능적 성공에 영향을 미친다고 볼 수 있다.

Abstract

Purpose: To report the effect and visual improvement of internal limiting membrane (ILM) peeling, and epiretinal membrane (ERM) peeling in symptomatic ERM with pseudolamellar macular hole. Methods: This study included 27 eyes in 26 consecutive patients with ERM including pseudolamellar macular hole that underwent vitrectomy, ERM peeling, intravitreal gas tamponade, and maintained a face-down position for 7 days. ILM peeling was performed only in 13 eyes of 13 patients. The patients were divided into 2 groups: eyes with or without ILM peeling (14 eyes and 13 eyes, respectively) and the follow-up period was 12 months or more in all cases. The postoperative anatomic results based on optical coherence tomography (OCT) and improvement of best corrected visual acuity (BCVA)were retrospectively compared between the 2 groups. Results: Anatomic closure after surgery was achieved in 11 eyes (78.6%) in the ILM without peeling group and in 12 eyes (92.3%) in the ILM with peeling group (p = 0.596). The BCVA improved from 0.41 ± 0.31 (log MAR) to 0.33 ± 0.21 in the ILM without peeling group (p = 0.479) and from 0.46 ± 0.41 (log MAR) to 0.28 ± 0.25 in the ILM with peeling group (p = 0.001). Conclusions: ILM peeling with the addition of ERM peeling is an effective technique for BCVA improvement in the ERM with pseudolamellar macular hole. Vitrectomy, ERM peeling, gas tamponade, and ILM peeling are important for anatomic and functional success in the ERM with pseudolamellar macular hole.

참고문헌 (29)

  1. Gass JD, "Lamellar macular hole: a complication of cystoid macular edema after cataract extraction: a clinicopathologic case report", Trans Am Ophthalmol Soc, 73, pp.231~250 (1975)
  2. Allen AW Jr, "Contraction of a perifoveal epiretinal membrane simulating a macular hole", Am J Ophthalmol, 82, pp.684~691 (1976)
  3. Gass JDM, "Vitreofoveal separation and lamellar hole formation Steroscopic atlas of macular disease: diagnosis and treatment", pp.926~927, CV Mosby
  4. Takahashi H, "Tomographic features of a lamellar macular hole formation and a lamellar hole that progressed to a full-thickness macular hole", Am J Ophthalmol, 130, pp.677~679 (2000)
  5. Haouchine B, "Diagnosis of macular pseudoholes and lamellar macular holes by optical coherence tomography", Am J Ophthalmol, 138, pp.732~739 (2004)
  6. Witkin AJ, "Redefining lamellar holes and the vitreomacular interface: an ultrahigh-resolution optical coherence tomography study", Ophthalmology, 113, pp.388~397 (2006)
  7. Chen JC, "Clinical spectrum of lamellar macular defects including pseudoholes and pseudocysts defined by optical coherence tomography", Br J Ophthalmol, 92, pp.1342~1346 (2008)
  8. Androudi S, "Lamellar macular holes: tomographic features and surgical outcome", Am J Ophthalmol, 148, pp.420~426 (2009)
  9. Kinoshita T, "Morphologic differences in epiretinal membranes on ocular coherence tomography as a predictive factor for surgical outcome", Retina, 31, pp.1692~1698 (2011)
  10. Kelly NE, "Vitreous surgery for idiopathic macular holes. Results of a pilot study", Arch Ophthalmol, 109, pp.654~659 (1991)
  11. Haouchine B, "Foveal pseudocyst as the first step in macular hole formation: a prospective study by optical coherence tomography", Ophthalmology, 108, pp.15~22 (2001)
  12. Michalewski J, "Evolution from macular pseudohole to lamellar macular hole - spectral domain OCT study", Graefes Arch Clin Exp Ophthalmol, 249, pp.175~178 (2011)
  13. Fine BS, "Limiting membranes of the sensory retina and pigment epithelium. An electron microscopic study", Arch Ophthalmol, 66, pp.847~860 (1961)
  14. de Bustros S, "Vitrectomy for idiopathic epiretinal membranes causing macular pucker", Br J Ophthalmol, 72, pp.692~695 (1988)
  15. de Bustros S, "Vitrectomy for macular pucker. Use after treatment of retinal tears or retinal detachment", Arch Ophthalmol, 106, pp.758~760 (1988)
  16. Mittleman D, "Clinicopathologic correlation of an eye after surgical removal of an epiretinal membrane", Retina, 9, pp.143~147 (1989)
  17. Witkin AJ, "Anatomic and visual outcomes of vitrectomy for lamellar macular holes", Ophthalmic Surg Lasers Imaging, 41, pp.418~424 (2010)
  18. Michalewska Z, "Surgical treatment of lamellar macular holes", Graefes Arch Clin Exp Ophthalmol, 248, pp.1395~1400 (2010)
  19. Garretson BR, "Vitrectomy for a symptomatic lamellar macular hole", Ophthalmology, 115, pp.884~886 (2008)
  20. Haritoglou C, "Macular changes after peeling of the internal limiting membrane in macular hole surgery", Am J Ophthalmol, 132, pp.363~368 (2001)
  21. Uemoto R, "Epimacular proliferative response following internal limiting membrane peeling for idiopathic macular holes", Graefes Arch Clin Exp Ophthalmol, 242, pp.177~180 (2004)
  22. Simddy WE, "Internal limiting membrane peeling in macular hole Surgery", Ophthalmology, 108, pp.1471~1478 (2001)
  23. Engelbrecht NE, "Retinal pigment epithelial changes after macular hole surgery with indocyanine green-assisted internal limiting membrane peeling", Am J Ophthalmol, 133, pp.89~94 (2002)
  24. Gale JS, "Comparison of the in vitro toxicity of green to that of trypan blue in human retinal pigment epithelium cell cultures", Am J Ophthalmol, 138, pp.64~69 (2004)
  25. Umeura A, "Visual field defects after uneventful vitrectomy for epiretinal membrane with indocyanine green-assisted internal limiting membrane peeling", Am J Ophthalmol, 136, pp.252~257 (2003)
  26. Kwok AK, "Macular hole surgery with or without indocyanine green stained internal limiting peeling", Clin Exp Ophthalmol, 31, pp.470~475 (2003)
  27. 박운철, "특발성 황반원공의 내경계막 제거 시 트리암시놀론 아세토나이드와 인도사이아닌그린의 비교", 대한안과학회지, 46(12), pp.1995~2003 (2005), 대한안과학회
  28. Lee SJ, "Long-term surgical outcomes after vitrectomy for symptomatic lamellar macular holes", Retina, 32, pp.1743~1748 (2012)
  29. 조원빈, "증상이 있는 표층황반원공 환자에서 시행한 유리체절제술 4예", 대한안과학회지, 50(9), pp.1427~1431 (2009), 대한안과학회

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