50세 미만 성인 백내장 환자에서 야그레이저 후낭절개술의 빈도와 위험인자
Incidence and Risk Factors of Nd:YAG Capsulotomy in Adult Cataract Patients Younger than 50 Years of Age
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목적: 50세 미만 성인 백내장 환자에서 후낭혼탁의 발생으로 후낭절개술을 시행 받은 빈도와 위험인자에 대해 분석하였다. 대상과 방법: 수정체초음파유화술과 인공수정체삽입술을 시행 받은 118안을 후향적으로 조사하였다. 후낭절개술 시행의 누적발생률을분석하였고, 백내장 형태, 인공수정체 종류, 성별, 당뇨와 녹내장 여부에 따른 통계적 분석으로 위험인자를 알아보았다. 결과: 백내장 수술 후 3개월, 6개월, 12개월, 24개월, 24개월 이상 관찰시, 후낭절개술의 누적발생률은 각각 4.24, 5.08, 8.47, 15.25,20.34%였다. 핵형(p=0.021)과 과숙형(p=0.014) 백내장에서 후낭절개술 시행률이 높았다. 수술시 삽입한 인공수정체 중에서 소수성일체형의 인공수정체가 후낭절개술 시행률이 낮았다(p=0.028). 성별, 당뇨, 녹내장의 유무는 후낭절개술과 통계적으로 유의하게 관련이 없었다(p>0.05). 결론: 백내장 수술 후 24개월 이상 관찰시, 후낭혼탁으로 인한 후낭절개술의 빈도는 20.34%였다. 핵형과 과숙형의 백내장이 후낭절개술 시행의 위험인자임을 알 수 있었고, 수술시 삽입하는 인공수정체의 종류에 따라 후낭혼탁의 발생률이 달랐다.
Abstract
Purpose: To evaluate the cumulative incidence and estimate the risk factors of Nd:YAG capsulotomy due to posterior capsular opacification in adult cataract patients younger than 50 years of age. Methods: In the present study we retrospectively reviewed 118 consecutive eyes that received phacoemulsification and intraocular lens implantation. We analyzed the cumulative incidence of Nd:YAG posterior capsulotomy and the associated risk factors. Results: The cumulative incidence of posterior capsulotomy was 4.24%, 5.08%, 8.47%, 15.25%, and 20.34% in adults younger than 50 years of age at 3 months, 6 months, 12 months, 24 months, and more than 24 months after cataract surgery,respectively. The nuclear type (p = 0.021) and the mature type (p = 0.014) cataract groups were strongly associated with an increased risk of posterior capsulotomy compared with the posterior subcapsular type. The hydrophobic and single-piece intraocular lens caused the lowest incidence of posterior capsulotomy among intraocular lenses used for cataract surgery (p = 0.028). The subgroup analysis showed no statistical significance between gender, existence of diabetic mellitus or glaucoma, intraocular lens haptic material and the risk of posterior capsulotomy (p > 0.05). Conclusions: The cumulative incidence of Nd:YAG capsulotomy was 20.34% in adults younger than 50 years of age and at more than 24 months after cataract surgery. The risk factors associated with posterior capsulotomy included nuclear and mature cataract types. Additionally, there was a difference in the incidence of posterior capsulotomy according to the type of intraocular lenses.
참고문헌 (33)
- Apple DJ, "Posterior capsule opacification", Surv Ophthalmol, 37, pp.73~116 (1992)
- Clark DS, "Posterior capsule opacification", Curr Opin Ophthalmol, 11, pp.56~64 (2000)
- Awasthi N, "Posterior capsule opacification : a problem reduced but not yet eradicated", Arch Ophthalmol, 127, pp.555~562 (2009)
- Cobo ML, "Pathogenesis of capsular opacification after extracapsular cataract extraction: an animal medel", Ophthalmology, 91, pp.857~863 (1984)
- Nishi O, "Posterior capsule opacification. Part 1. Experimental investigations", J Cataract Refract Surg, 25, pp.106~117 (1999)
- Miyake K, "Liquefied aftercataract: a complication of continuous curvilinear capsulorhexis and intraocular lens implantation in the lens capsule", Am J Ophthalmol, 125, pp.429~435 (1998)
- Meacock WR, "Role of cytokines in the pathogenesis of posterior capsule opacification", Br J Ophthalmol, 84, pp.332~336 (2000)
- Baratz KH, "Probability of Nd:YAG laser capsulotomy after cataract surgery in Olmsted County, Minnesota", Am J Ophthalmol, 131, pp.161~166 (2001)
- Ando H, "Cumulative probability of neodymium: YAG laser posterior capsulotomy after phacoemulsification", J Cataract Refract Surg, 29, pp.2148~2154 (2003)
- Liu CS, "A study of human lens cell growth in vitro. A model for posterior capsule opacification", Invest Ophthalmol Vis Sci, 37, pp.906~914 (1996)
- Wormstone IM, "Human lens epithelial cell proliferation in a protein-free medium", Invest Ophthalmol Vis Sci, 38, pp.396~404 (1997)
- Dholakia SA, "Prospective evaluation of phacoemulsification in adults younger than 50 years", J Cataract Refract Surg, 31, pp.1327~1333 (2005)
- Schaumberg DA, "A systematic overview of the incidence of posterior capsule opacification", Ophthalmology, 105, pp.1213~1221 (1998)
- 정해웅, "PMMA, 실리콘, 아크릴 인공수정체의 후낭혼탁 및 후낭절개술", 대한안과학회지, 44(5), pp.11~1078 (2003), 대한안과학회
- Lambert SR, "Long-term outcomes of undercorrection versus full correction after unilateral intraocular lens implantation in children", Am J Ophthalmol, 153, pp.602~608 (2012)
- Oliver M, "Posterior chamber lens implantation in infants and juveniles", Eur J Implant Ref Surg, 2, pp.309~314 (1990)
- Hiroshi A, "Cumulative probability of neodymium : YAG laser posterior capsulotomy after phacoemulsification", J Cataract Refract Surg, 29, pp.2148~2154 (2003)
- Argento C, "Study of the lens epithelial cell density in cataractous eyes operated on with extracapsular and intercapsular techniques", J Cataract Refract Surg, 16, pp.207~210 (1990)
- 이민정, "백내장 수술 후 후낭 혼탁의 조기 발생에 영향을 주는 요인", 대한안과학회지, 48(4), pp.493~498 (2007), 대한안과학회
- Stark WJ, "Neodymium: YAG lasers. An FDA report", Ophthalmology, 92, pp.209~212 (1985)
- Aykan U, "The effect of capsulorhexis size on development of posterior capsule opacification: small (4.5 to 5.0 mm) versus large (6.0 to 7.0 mm)", Eur J Ophthalmol, 13, pp.541~545 (2003)
- Bolz M, "Effect of anterior capsule polishing on the posterior capsule opacification-inhibiting properties of a sharp-edged, 3-piece, silicone intraocular lens: three- and 5-year results of a randomized trial", J Cataract Refract Surg, 32, pp.1513~1520 (2006)
- Hollick EJ, "The effect of capsulorhexis size on posterior capsular opacification: one-year results of a randomized prospective trial", Am J Ophthalmol, 128, pp.271~279 (1999)
- Sacu S, "Effect of anterior capsule polishing on fibrotic capsule opacification: three-year results", J Cataract Refract Surg, 30, pp.2322~2327 (2004)
- 서상원, "후발백내장 발생에 영향을 미치는 요인에 대한 연구", 대한안과학회지, 42(12), pp.1685~1690 (2001), 대한안과학회
- Hayashi K, "Posterior capsule opacification after implantation of a hydrogel intraocular lens", Br J Ophthalmol, 88, pp.182~185 (2004)
- Heatley CJ, "Comparison of posterior capsule opacification rates between hydrophilic and hydrophobic single-piece acrylic intraocular lenses", J Cataract Refract Surg, 31, pp.718~724 (2005)
- Kugelberg M, "Posterior capsule opacification after implantation of a hydrophilic or a hydrophobic acrylic intraocular lens: one-year follow-up", J Cataract Refract Surg, 32, pp.1627~1631 (2006)
- Kugelberg M, "Two-year follow- up of posterior capsule opacification after implantation of a hydrophilic or hydrophobic acrylic intraocular lens", Acta Ophthalmol, 86, pp.533~536 (2008)
- Roesel M, "Uveal and capsular biocompatibility of two foldable acrylic intraocular lenses in patients with endogenous uveitisda prospective randomized study", Graefes Arch Clin Exp Ophthalmol, 246, pp.1609~1615 (2008)
- Saeed MU, "Intraocular lens and capsule opacification with hydrophilic and hydrophobic acrylic materials", Semin Ophthalmol, 27, pp.15~18 (2012)
- Mian SI, "Nd:YAG capsulotomy rates after use of the AcrySof acrylic three piece and one piece intraocular lenses", Br J Ophthalmol, 89, pp.1453~1457 (2005)
- Abela-Formanek C, "Results of hydrophilic acrylic, hydrophobic acrylic, and silicone intraocular lenses in uveitic eyes with cataract: comparison to a control group", J Cataract Refract Surg, 28, pp.1141~1152 (2002)
