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비만 지수와 안압과의 관계

Cross-Sectional Study between Anthropometric Obesity Indices and Intraocular Pressure

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주제분류안과학

초록

목적: 비만을 나타내는 건강지수들과 안압의 상관관계를 단면연구를 통해 알아보고자 하였다. 대상과 방법: 정상인을 대상으로 연령, 성별에 따른, 건강지수들 즉 비만도, 체질량지수, 체형지수, 허리둘레‐신장비율과 정상, 과체중,비만에 따른 안압과의 상관관계를 조사하였다. 결과: 총 63,385명의 환자 중 남자가 30,288명, 여자가 33,097명이었으며, 평균 안압은 남자가 15.13 ± 3.24 mmHg, 여자가 14.44± 3.02 mmHg이었다. 비만도와 체질량지수와 연관된 남, 여의 안압이 모두 정상, 과체중, 비만으로 나눈 3군 사이에 유의한 차이를보였으며(p<0.05), 비만으로 갈수록 각 군의 평균값이 증가하였다. 체형지수에 따라 나눈 정상, 과체중, 비만에서는 3군 사이에 여자(p=0.28), 남자(p=0.66) 모두 안압의 유의한 차이가 없었다. 허리둘레‐신장비율에 따라 나눈 3군에서는 성별의 차이 없이 정상과 과체중, 정상과 비만 사이에 안압이 유의한 차이를 보였다(p<0.05). 다중 선형 회귀분석에서 남, 여 모두 비만도, 체질량지수, 체형지수,허리둘레‐신장비율에서 안압과 연관성을 보였고, ROC curve에서는 비만도, 체질량지수, 허리둘레‐신장비율, 체형지수 순으로 높은수치를 나타내었다. 결론: 한국의 정상인에 있어서 성별에 상관없이 안압은 비만도, 체질량지수, 체형지수, 허리둘레‐신장비율에서 연관성을 가지고 있으며, 그중 비만도와 가장 밀접한 연관성이 있었다.

Abstract

Purpose: To investigate the cross sectional study association of intraocular pressure (IOP) with anthropometric obesity indices. Methods: We classified study subjects into three groups‐‐normal, overweight and obesity, and investigated the correlation of IOPwith age, gender and anthropometric obesity indices such as obesity Index, body mass index (BMI), a body shape index (ABSI)and waist to height ratio (WHtR) on healthy subjects. Results: Of a total of 63,385 participants, 30,288 were male and 33,097 were female. Mean IOP was 15.13 ± 3.24 mm Hg formen and 14.44 ± 3.02 mm Hg for women. The obesity index and BMI in the normal, overweight and obesity groups were significantlydifferent in both men and women (p < 0.05). Mean IOP increased to a higher degree in the obesity group. In the normal,overweight and obesity group divided by ABSI, there were no significant differences in both men (p = 0.66) and women (p =0.28). Between the normal and overweight group and the normal and obesity group divided by WHtR, there were significant differencesin men (p < 0.05) and women (p < 0.05). Multiple linear regression analysis showed the significant relationship betweenobesity index, BMI, ABSI, WHtR and IOP in men and women. Receiver operating characteristic curve showed that the obesity indexwas the highest value following BMI, WHtR and ABSI. Conclusions: Korean healthy subjects showed a correlation between IOP and anthropometric obesity indices regardless of gender,and the obesity index had the highest correlation.

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