국민건강영양조사 자료를 이용하여 분석한 안압과 전신적인 지표와의 관계
Associations between Intraocular Pressure and Systemic Parameters according to the KNHNES 2008-2011
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목적: 국민건강영양조사 자료를 이용하여 안압과 전신적인 지표 및 사회경제적인 지표와의 관계를 알아보고자 하였다. 대상과 방법: 국민건강영양조사 2008-2011 중에서 20세 이상이면서 녹내장이 없고 안과적 수술력이 없는 대상자 중 안압이 측정되어 있는 남자 6,606명, 여자 9,684명, 총 15,421명을 대상으로 하였다. 결과: 단변량 회귀분석 결과, 연령(p=0.001), body mass index (BMI), 흡연, 음주량, 수축기 혈압, 공복혈당, 총 콜레스테롤, 중성지방, 인슐린, homeostasis model assessment of insulin resistance (HOMA-IR), 대사증후군(p<0.001, respectively), LDL (p=0.003), 사무직(p=0.029) 등의 전신적 및 사회경제적인 지표와 굴절이상(p<0.001)이 안압과 통계적으로 유의한 선형 상관관계를 보였다. 다변량회귀분석 결과, 연령, BMI, 수축기 혈압, 공복혈당, 총 콜레스테롤(p<0.001, respectively), 음주량(p=0.013) 등의 전신적 및 사회경제적인 지표와 굴절이상(p<0.001)이 안압과 통계적으로 유의한 선형 상관관계를 보였다. 또한 직업군에 따른 안압, 굴절이상 값의 분산분석 결과, 직업군별로 안압, 굴절이상 값에 통계적으로 유의한 차이가 있음을 확인할 수 있었다(p<0.001, all). 결론: 국민건강영양조사 자료의 전신적인 지표와 사회경제적인 지표 중 연령, BMI, 음주량, 수축기 혈압, 공복혈당, 총 콜레스테롤 등의 전신적 및 사회경제적인 지표와 굴절이상이 안압과 통계적으로 유의한 상관관계를 보였으며, 직업군별로 안압, 굴절이상 값에 통계적으로 유의한 차이가 있었다.
Abstract
Purpose: In this study, we evaluated the associations between intraocular pressure (IOP) and systemic and socioeconomic factors. Methods: A population-based cross-sectional study using a nation-wide, stratified, multistage, clustered sampling method included 15,421 subjects aged ≥20 years with no history of ocular surgery or glaucoma who participated in the Korean National Health and Nutritional Examination Survey 2008-2011. Results: Univariate regression analyses showed statistically significant linear relationships between IOP and body mass index (BMI), smoking status, heavy drinking, systolic blood pressure, fasting blood glucose, total cholesterol, triglycerides, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), metabolic syndrome (p < 0.001, respectively), low density lipoprotein cholesterol (p = 0.003), refractive error (p < 0.001), and office work (p = 0.029). In addition, analysis of variance (ANOVA) showed statistically significant differences in IOP and refraction according to occupation (p < 0.001, all). Conclusions: We concluded that increased IOP was associated with age, BMI, heavy drinking, systolic blood pressure, total cholesterol, and refraction. There were statistically significant differences in IOP and refraction according to occupation.
참고문헌 (26)
- Kass MA, "The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma", Arch Ophthalmol, 120, pp.701~713 (2002)
- Higginbotham EJ, "The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals", Arch Ophthalmol, 122, pp.813~820 (2004)
- Sommer A, "Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans. The Baltimore Eye Survey", Arch Ophthalmol, 109, pp.1090~1095 (1991)
- Dielemans I, "Primary open-angle glaucoma, intraocular pressure, and systemic blood pressure in the general elderly population. The Rotterdam Study", Ophthalmology, 102, pp.54~60 (1995)
- Hennis A, "Hypertension, diabetes, and longitudinal changes in intraocular pressure", Ophthalmology, 110, pp.908~914 (2003)
- Mitchell P, "Open-angle glaucoma and diabetes: the Blue Mountains eye study, Australia", Ophthalmology, 104, pp.712~718 (1997)
- Aydin P, "Effect of wind instrument playing on intraocular pressure", J Glaucoma, 9, pp.322~324 (2000)
- 이응, "한국 해녀에서 지식잠수 활동이 안압과 시신경 및 시야에 미치는 영향", 대한안과학회지, 53(10), pp.1480~1487 (2012), 대한안과학회[DOI]
- Jang HD, "Relationship between intraocular pressure and parameters of obesity in Korean adults: The 2008-2010 Korea National Health and Nutrition Examination Survey", Curr Eye Res, 40, pp.1008~1017 (2015)
- Chun YH, "Insulin resistance is associated with intraocular pressure elevation in a non-obese Korean population", PLoS One, 10, pp.e112929~ (2015)
- Gwiazda J, "Association of education and occupation with myopia in COMET parents", Optom Vis Sci, 88, pp.1045~1053 (2011)
- Shimizu N, "Refractive errors and factors associated with myopia in an adult Japanese population", Jpn J Ophthalmol, 47, pp.6~12 (2003)
- Wong TY, "Education, socioeconomic status, and ocular dimensions in Chinese adults: the Tanjong Pagar Survey", Br J Ophthalmol, 86, pp.963~968 (2002)
- Choi JA, "Age-related association of refractive error with intraocular pressure in the Korea National Health and Nutrition Examination Survey", PLoS One, 9, pp.111879~ (2014)
- Kim KE, "Prevalence, awareness, and risk factors of primary open-angle glaucoma: Korea National Health and Nutrition Examination Survey 2008-2011", Ophthalmology, 123, pp.532~541 (2016)
- 박현아, "The Korea National Health and Nutrition Examination Survey as a Primary Data Source", Korean Journal of Family Medicine, 34(2), pp.79~79 (2013), 대한가정의학회
- 김양호, "Inappropriate Survey Design Analysis of the Korean National Health and Nutrition Examination Survey May Produce Biased Results", 예방의학회지, 46(2), pp.96~104 (2013), 대한예방의학회
- 임형택, "호르몬 대체요법과 안 질환: 제4기 국민건강영양조사자료", 대한안과학회지, 53(10), pp.1445~1450 (2012), 대한안과학회[DOI]
- Lim SG, "Association between insulin resistance and periodontitis in Korean adults", J Clin Periodontol, 41, pp.121~130 (2014)
- 김윤경, "개방각녹내장과 뇌척수압 및 사상판경유압력차의 관계: 제5기 국민건강영양조사 자료", 대한안과학회지, 57(9), pp.1392~1399 (2016), 대한안과학회
- Flammer J, "The impact of ocular blood flow in glaucoma", Prog Retin Eye Res, 21, pp.359~393 (2002)
- Schuman JS, "Increased intraocular pressure and visual field defects in high resistance wind instrument players", Ophthalmology, 107, pp.127~133 (2000)
- Baskaran M, "Intraocular pressure changes and ocular biometry during Sirsasana (headstand posture)in yoga practitioners", Ophthalmology, 113, pp.1327~1332 (2006)
- Wu SY, "Nine-year changes in intraocular pressure: the Barbados Eye Studies", Arch Ophthalmol, 124, pp.1631~1636 (2006)
- Yoshida M, "Association of life-style with intraocular pressure in middle-aged and older Japanese residents", Jpn J Ophthalmol, 47, pp.191~198 (2003)
- Gasch AT, "Determinants of glaucoma awareness in a general eye clinic", Ophthalmology, 107, pp.303~308 (2000)