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원발급성폐쇄각발작에서 레이저홍채절개술에 이은 조기수정체적출술 병합치료의 효과

Clinical Outcomes of Early Phacoemulsification after Laser Iridotomy in Acute Angle-closure Glaucoma

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목적: 원발급성폐쇄각발작 환자에서 발작안에 레이저홍채절개술만 시행한 환자군과 레이저홍채절개술에 이은 조기 수정체적출술을 시행한 환자군에 대해 장기간의 안압 변화를 알아보았다. 대상과 방법: 후향적 의무기록 분석을 통해 원발급성폐쇄각발작으로 내원하여 발작안에 레이저홍채절개술만을 시행한 환자군(A군)과 1달 이내 레이저홍채절개술에 이은 수정체적출술을 시행한 환자군(B군)을 대상으로 조사하였다. 내원한 초진 시부터 12개월까지 A, B군에 대해 안압 변화를 알아보았다. 결과: 총 대상 환자는 99명으로 A군 37명, B군 62명이었다. A, B군 간의 각 시기별 평균 안압은 수술 후 1개월째 유의한 차이를 보이지 않았으나, 3개월, 6개월, 12개월째 B군이 A군에 비해 유의하게 낮은 양상을 보였다(p=0.003, <0.001, <0.001). 두 군 간 안압의 재상승(IOP ≥ 21 mmHg) 빈도는 3개월, 6개월, 12개월에 각각 A군은 3명(8.11%), 5명(13.51%), 5명(13.51%), B군 0명, 2명(5.41%), 1명(1.61%)으로 유의하게 B군에 안압의 재상승 빈도가 낮았다(p=0.050, 0.038, 0.026). 결론: 레이저홍채절개술에 이은 조기 수정체적출 시행 후 1년간의 관찰 결과 성공적으로 안압 조절이 가능하였으며 레이저홍채절개술만 시행한 군에 비해 안정적인 결과를 보였다. 본 연구를 통해 원발급성폐쇄각발작 환자에서 백내장이 동반된 경우 레이저홍채절개술에 이은 조기 수정체적출술은 장기적 치료 효과 측면에서 권장할 만한 방법으로 판단된다.

Abstract

Purpose: To evaluate long-term change in intraocular pressure (IOP) in eyes undergoing laser iridotomy (LI) and early phacoemulsification after LI in patients with acute angle-closure glaucoma (AACG). Methods: The retrospective, comparative chart review included patients with AACG, Group A who underwent only LI and Group B who underwent early phacoemulsification within 1 month after LI. Patients were followed up on day 1; week 1; and months 1, 3, 6, and 12 after LI. IOP changes were studied. Results: This study included a total 99 eyes from 99 patients, 37 in group A and 62 in group B. The mean IOP were not significantly different between the two groups at the initial visit or 1 month later. However, group B showed a consistently lower mean IOP that that of group A at 3, 6, and 12 months (p = 0.003, <0.001, <0.001, respectively). The prevalence of IOP increase to greater than 21 mmHg was 3 (8.11%), 5 (13.51%), and 5 patients (13.51%) in group A and 0, 2 (5.41%), and 1 patients (1.61%) in group B at 3, 6, and 12 months, respectively. Group B showed a significantly lower prevalence of IOP increase (p = 0.050, 0.038, 0.026). Conclusions: We found that patients treated with early phacoemulsification after LI had better outcomes of well-maintained IOP compared to those undergoing LI alone. For AACG patients with coexisting cataract, early phacoemulsification after LI can be considered as a reasonable treatment to maintain IOP.

참고문헌 (29)

  1. Kim YY., "Angle closure in the Namil study in central South Korea", Arch Ophthalmol, 130, pp.1177~1183 (2012)
  2. Kim CS., "Prevalence of primary open-angle glaucoma in central South Korea the Namil study", Ophthalmology, 118, pp.1024~1030 (2011)
  3. Quigley HA, "Number of people with glaucoma worldwide", Br J Ophthalmol, 80, pp.389~393 (1996)
  4. Robin AL., "Argon laser peripheral iridotomies in the treatment of primary angleclosure glaucoma. Long-term follow-up", Arch Ophthalmol, 100, pp.919~923 (1982)
  5. Salmon JF, "Long-term intraocular pressure control after Nd-YAG laser iridotomy in chronic angle-closure glaucoma", J Glaucoma, 2, pp.291~296 (1993)
  6. Lam DS., "Argon laser peripheral iridoplasty versus conventional systemic medical therapy in treatment of acute primary angle-closure glaucoma : a prospective, randomized, controlled trial", Ophthalmology, 109, pp.1591~1596 (2002)
  7. Aung T., "Acute primary angle-closure : long-term intraocular pressure outcome in Asian eyes", Am J Ophthalmol, 131, pp.7~12 (2001)
  8. Ming Zhi Z., "A pilot study of lens extraction in the management of acute primary angle-closure glaucoma", Am J Ophthalmol, 135, pp.534~536 (2003)
  9. Tarongoy P., "Angle-closure glaucoma : the role of the lens in the pathogenesis, prevention, and treatment", Surv Ophthalmol, 54, pp.211~225 (2009)
  10. Hayashi K., "Effect of cataract surgery on intraocular pressure control in glaucoma patients", J Cataract Refract Surg, 27, pp.1779~1786 (2001)
  11. Jacobi PC., "Primary phacoemulsification and intraocular lens implantation for acute angle-closure glaucoma", Ophthalmology, 109, pp.1597~1603 (2002)
  12. Pereira FA., "Ultrasound biomicroscopic study of anterior segment changes after phacoemulsification and foldable intraocular lens implantation", Ophthalmology, 110, pp.1799~1806 (2003)
  13. Chen YY., "The biometric study in different stages of primary angle-closure glaucoma", Eye(Lond), 27, pp.1070~1076 (2013)
  14. Shams PN., "Clinical outcomes after lens extraction for visually significant cataract in eyes with primary angle closure", J Glaucoma, 21, pp.545~550 (2012)
  15. Musch DC., "Cataract extraction in the collaborative initial glaucoma treatment study : incidence, risk factors, and the effect of cataract progression and extraction on clinical and quality-of-life outcomes", Arch Ophthalmol, 124, pp.1694~1700 (2006)
  16. Lowe RF., "Aetiology of the anatomical basis for primary angle-closure glaucoma. Biometrical comparisons between normal eyes and eyes with primary angle-closure glaucoma", Br J Ophthalmol, 54, pp.161~169 (1970)
  17. Foster PJ., "The definition and classification of glaucoma in prevalence surveys", Br J Ophthalmol, 86, pp.238~242 (2002)
  18. Chen Y., "Morphologic changes in the anterior chamber in patients with cortical or nuclear age-related cataract", J Cataract Refract Surg, 37, pp.77~82 (2011)
  19. Erie JG., "The incidence of primary angle-closure glaucoma in Olmsted County, Minnesota", Arch Ophthalmol, 115, pp.177~181 (1997)
  20. Ritch R., "The Glaucomas: Glaucoma Therapy", pp.1521~1531 (1996), Mosby
  21. Strorey JK., "Ocular dimensions in angle closure glaucoma", Br J Physiol Optics, 26, pp.228~242 (1971)
  22. Nonaka A., "Cataract surgery for residual angle closure after peripheral laser iridotomy", Ophthalmology, 112, pp.974~979 (2005)
  23. Nonaka A., "Angle widening and alteration of ciliary process configuration after cataract surgery for primary angle closure", Ophthalmology, 113, pp.437~441 (2006)
  24. Lam DS., "Randomized trial of early phacoemulsification versus peripheral iridotomy to prevent intraocular pressure rise after acute primary angle closure", Ophthalmology, 115, pp.1134~1140 (2008)
  25. Dada T., "Clinical outcomes of clear lens extraction in eyes with primary angle closure", J Cataract Refract Surg, 41, pp.1470~1477 (2015)
  26. Trikha S., "The role of lens extraction in the current management of primary angle-closure glaucoma", Curr Opin Ophthalmol, 26, pp.128~134 (2015)
  27. Azuara-Blanco A., "The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma(EAGLE) : study protocol for a randomized controlled trial", Trials, 12, pp.133~ (2011)
  28. Sihota R., "The trabecular meshwork in acute and chronic angle closure glaucoma", Indian J Ophthalmol, 49, pp.255~259 (2001)
  29. 이경민, "급성 폐쇄각녹내장에서 합병증을 중심으로 본 초음파유화술의 임상결과", 대한안과학회지, 50(1), pp.44~50 (2009), 대한안과학회

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