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부갑상선기능항진증으로 발생한 하악골 갈색종 1예

A Case of Brown Tumor of the Mandible Caused by Hyperparathyroidism

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주제분류이비인후과학

초록

Brown tumors are erosive bony lesions caused by the chronic excessive secretion of parathyroid hormone. Since the introduction of routine calcium measurement, the diagnosis of hyperparathyroidism has usually been made in asymptomatic patients, and as a result, brown tumors are rarely observed as an initial manifestation of hyperparathyroidism. The authors report a case of a 32-year-old woman who presented with right cheek swelling. A CT scan showed erosive bone tumors of the mandible. These lesions were finally diagnosed as brown tumors associated with secondary hyperparathyroidism due to chronic renal failure. Brown tumor as a result of hyperparathyroidism is a relatively rare clinical finding in otorhinolaryngology, thus, the authors illustrate this case with a brief review of the literature. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:716-8

Abstract

Brown tumors are erosive bony lesions caused by the chronic excessive secretion of parathyroid hormone. Since the introduction of routine calcium measurement, the diagnosis of hyperparathyroidism has usually been made in asymptomatic patients, and as a result, brown tumors are rarely observed as an initial manifestation of hyperparathyroidism. The authors report a case of a 32-year-old woman who presented with right cheek swelling. A CT scan showed erosive bone tumors of the mandible. These lesions were finally diagnosed as brown tumors associated with secondary hyperparathyroidism due to chronic renal failure. Brown tumor as a result of hyperparathyroidism is a relatively rare clinical finding in otorhinolaryngology, thus, the authors illustrate this case with a brief review of the literature. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:716-8

참고문헌 (12)

  1. 천병준, "원발성 부갑상샘 기능항진증에 의해 속발한 경구개 갈색종 1예", 대한이비인후과학회지 두경부외과학, 52(7), pp.612~615 (2009), 대한이비인후과학회
  2. Gonzalez-Martínez E, "Brown tumor of the orbital roof as an initial and isolated manifestation of secondary hyperparathyroidism", Orbit, 29(5), pp.278~280 (2010)
  3. Kaya RA, "Spinal cord compression caused by a brown tumor at the cervicothoracic junction", Spine J, 7(6), pp.728~732 (2007)
  4. Jouan A, "An unusual presentation of primary hyperparathyroidism: severe hypercalcemia and multiple brown tumors", Joint Bone Spine, 75(2), pp.209~211 (2008)
  5. Daniels JS, "Primary hyperparathyroidism presenting as a palatal brown tumor", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 98(4), pp.409~413 (2004)
  6. Blinder G, "Brown tumor in the cricoid cartilage: an unusual manifestation of primary hyperparathyroidism", Ann Otol Rhinol Laryngol, 106(3), pp.252~253 (1997)
  7. Scott SN, "Brown tumor of the palate in a patient with primary hyperparathyroidism", Ann Otol Rhinol Laryngol, 108(1), pp.91~94 (1999)
  8. Knezević G, "Primary hyperparathyroidism: evaluation of different treatments of jaw lesions based on case reports", Br J Oral Maxillofac Surg, (29)통권 : 3, pp.185~188 (1991)
  9. 최영우, "압박골절을 동반한 척추체의 갈색종: 증례 보고", 대한영상의학회지, 54(1), pp.33~37 (2006), 대한영상의학회
  10. Chung DW, "A brown tumor in metacarpal bone accompanied with primary hyperparathyroidism- a case report-", J Korean Soc Surg Hand, 11(1), pp.66~71 (2006)
  11. Kao HL, "Missed brown tumors in a young adult with decreased bone density", South Med J, 103(4), pp.371~373 (2010)
  12. Yamazaki H, "Brown tumor of the maxilla and mandible: progressive mandibular brown tumor after removal of parathyroid adenoma", J Oral Maxillofac Surg, 61(6), pp.719~722 (2003)

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