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이차성 부갑상선기능항진증과 갈색종을 동반한 비타민 D 결핍 환자 1예

A Case of Vitamin D Deficiency with Secondary Hyperparathyroidism and Brown Tumor

김태호|이재혁|김세화|이민경|강원식
대한골다공증학회 (THE KOREAN SOCIETY OF OSTEOPOROSIS)|2012.08|OSTEOPOROSIS (The Journal of Korean Society of Osteoporosis)|제10권 제2호|pp. 90-96

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참고문헌

키워드

OsteoporosisVitamin D deficiencyBrown tumorHyperparathyroidism
주제분류기타의약학

초록

The importance of vitamin D for skeletal health is well known. Vitamin D deficiency causes secondary hyperparathyroidism, high bone turnover, bone loss, and osteoporotic fractures. We report a case of a 60-year-old women presenting with brown tumor in the proximal femur secondary to vitamin D deficiency and secondary hyperparathyroidism. She took calcium supplements and vitamin D3 for 1 year and half dose of risedronate was prescribed for 5 months. After 1 year, pain in the pelvis was much improved and Bone mineral density of the lumbar spine and femoral neck increased by 37% and 29%, respectively.

Abstract

The importance of vitamin D for skeletal health is well known. Vitamin D deficiency causes secondary hyperparathyroidism, high bone turnover, bone loss, and osteoporotic fractures. We report a case of a 60-year-old women presenting with brown tumor in the proximal femur secondary to vitamin D deficiency and secondary hyperparathyroidism. She took calcium supplements and vitamin D3 for 1 year and half dose of risedronate was prescribed for 5 months. After 1 year, pain in the pelvis was much improved and Bone mineral density of the lumbar spine and femoral neck increased by 37% and 29%, respectively.

참고문헌 (28)

  1. Lips P, "Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications", Endocr Rev, 22, pp.477~501 (2001)
  2. Bischoff-Ferrari HA, "Positive association between 25- hydroxyvitamin D levels and bone mineral density: a population-based study of younger and older adults", Am J Med, 116, pp.634~639 (2004)
  3. Visser M, "Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam", J Clin Endocrinol Metab, 88, pp.5766~5772 (2003)
  4. Pfeifer M, "Vitamin D status, trunk muscle strength, body sway, falls and fractures among 237 postmenopausal women with osteoporosis", Exp Clin Endocrinol Diabetes, 109, pp.87~92 (2001)
  5. Van Schoor NM, "Vitamin D deficiency as a risk factor for osteoporotic fractures", Bone, 42, pp.260~266 (2008)
  6. Looker AC, "Serum 25-hydroxyvitamin D and hip fracture risk in older US white adults", J Bone Miner Res, 23, pp.143~150 (2008)
  7. Ginde AA, "Demorgraphic differences and trends of vitamin D insufficiency in the US population, 1988-2004", Arch Intern Med, 169, pp.626~632 (2009)
  8. Lips P, "The prevalence of vitamin D inadequacy amongst women with ostseoporosis: an international epidemiological investigation", J Intern Med, 260, pp.245~254 (2006)
  9. Choi HS, "Vitamin D insufficiency in Korea-A greater threat to younger generation: The Korean National Health and Nutrition Examination Survery (KNHANES) 2008", J Clin Endocrinol Metab, 96, pp.643~651 (2011)
  10. Diamanti-Kandarakis E, "Brown tumor of the fibula: unusual presentation of an uncommon manifestation. Report of a case and review of the literature", Endocrine, 32, pp.345~349 (2007)
  11. Scott SN, "Brown tumor of the palate in a patient with primary hyperparathyroidism", Ann Otol Rhinol Laryngol, 108, pp.91~94 (1999)
  12. Yamazaki H, "Brown tumor of the maxilla and mandible: progressive mandibular brown tumor after removal of parathyroid adenoma", J Oral Maxillofac Surg, 61, pp.719~722 (2003)
  13. Knezević G, "Primary hyperparathyroidism: evaluation of different treatments of jaw lesions based on case reports", Br J Oral Maxillofac Surg, 29, pp.185~188 (1991)
  14. Pace C, "Simultaneously occurring brown tumors in the mandible and maxilla in a patient with vitamin D deficiency", Aust Dental J, 55, pp.453~456 (2010)
  15. Barsić N, "Brown tumor- a rare manifestation of renal osteodystrophy and severe secondary hyperparathyroidism: case report", Acta Clin Croat, 49, pp.299~304 (2010)
  16. Sambrook PN, "Vitamin D deficiency is common in frail institutionalized older people in northern Sydney", Med J Aust, 176, pp.560~ (2002)
  17. Lee SK, "A case of mediastinal parathyroid adenoma presenting as fracture of brown tumor", Korean J Med, 56, pp.113~118 (1999)
  18. 목지영, "원발성 부갑상선 기능항진증에서 부갑상선 절제술 후 빠른 퇴행을 보인 갈색종 1예", Endocrinology and Metabolism, 25(1), pp.50~55 (2010), 대한내분비학회
  19. Tritos NA, "Rapid improvement of osteoporosis following parathyroidectomy in a premenopausal woman with acute primary hyperparathyroidism", Arch Intern Med, 159, pp.1495~1498 (1999)
  20. Silverberg SJ, "Increased bone mineral density after parathyroidectomy in primary hyperparathyroidism", J Clin Endocrinol Metab, 80, pp.729~734 (1995)
  21. Murphy E, "The thyroid hormone and the skeleton", Clin Endocrinol, 61, pp.285~298 (2004)
  22. Abe E, "TSH is a negative regulator of skeletal remodeling", Cell, 115, pp.151~162 (2003)
  23. Marians RC, "Defining thyrotropin-dependent and – independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice", Proc Natl Acad Sci, 99, pp.15776~15781 (2002)
  24. Shanmughan MS, "Hyperparathyroidism with osteitis fibrosa cystic in maxilla", J Laryngol Otol, 98, pp.417~420 (1984)
  25. Nabi Z, "Regression of brown tumor of the maxilla in a patient with secondary hyperparathyroidism after a parathyroidectomy", Hemodial Int, 14, pp.247~249 (2010)
  26. Kennett S, "Jaw lesions in familial hyperparathyroidism", Oral Surg Oral Med Oral Pathol, 31, pp.502~510 (1971)
  27. Slem G, "Brown tumor of the orbit", Ann Ophthalmol, 15, pp.811~812 (1983)
  28. Daniels JS, "Primary hyperparathyroidism presenting as a palatal brown tumor", Oral Surg Oral Med Oral Pathol Oral Endoc, 98, pp.409~413 (2004)

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