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Severe Facial Disfigurement Corrected by Parathyroidectomy: A Case Report and Literature Review

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초록

A case of incidental right maxilla brown tumour and radiological confirmation of osteitis fibrosa cystica as a result of primary hyperparathyroidism managed with parathyroidectomy, which complicated with post-operatively with hungry bone syndrome. The case exhibits the traditional finding of osteitis fibrosa cystica. The high degree of clinical suspicion of browns tumour is demonstrated which has prevented invasive procedures, as demonstrated in other case reports. Furthermore, the brown tumour was treated with parathyroidectomy along with the patient’s other systemic complications. Literature review confirms the systemic manifestation of hyperparathyroidism, which needs to be investigated and managed accordingly. Medical modalities of managing hyperparathyroidism are limited and surgery is currently the most efficient treatment option for managing primary hyperparathyroidism and its systemic complications.

Abstract

A case of incidental right maxilla brown tumour and radiological confirmation of osteitis fibrosa cystica as a result of primary hyperparathyroidism managed with parathyroidectomy, which complicated with post-operatively with hungry bone syndrome. The case exhibits the traditional finding of osteitis fibrosa cystica. The high degree of clinical suspicion of browns tumour is demonstrated which has prevented invasive procedures, as demonstrated in other case reports. Furthermore, the brown tumour was treated with parathyroidectomy along with the patient’s other systemic complications. Literature review confirms the systemic manifestation of hyperparathyroidism, which needs to be investigated and managed accordingly. Medical modalities of managing hyperparathyroidism are limited and surgery is currently the most efficient treatment option for managing primary hyperparathyroidism and its systemic complications.

참고문헌 (12)

  1. Nasser ML, "Osteitis fibrosa cystica mimicking bone tumor, a case report", BMC Musculoskelet Disord, 22, pp.479~ (2021)
  2. Parikh P, "Brown tumour mimicking skeletal metastasis", BMJ Case Rep, 14, pp.e243478~ (2021)
  3. Majumdar S, "Brown tumor of hyperparathyroidism with multiple lesions", J Oral Maxillofac Pathol, 26, pp.S111~S115 (2022)
  4. Zhong Y, "Misdiagnosis of brown tumour caused by primary hyperparathyroidism : a case report with literature review", BMC Endocr Disord, 22, pp.66~ (2022)
  5. Misiorowski W, "Osteitis fibrosa cystica", JBMR Plus, 4, pp.e10403~ (2020)
  6. Silva BC, "Skeletal abnormalities in hypoparathyroidism and in primary hyperparathyroidism", Rev Endocr Metab Disord, 22, pp.789~802 (2021)
  7. Usmael SA, "Osteitis fibrosa cystica; a forgotten manifestation of secondary hyperparathyroidism due to end-stage renal disease : a case report", Int Med Case Rep J, 15, pp.529~535 (2022)
  8. Minisola S, "Classical complications of primary hyperparathyroidism", Best Pract Res Clin Endocrinol Metab, 32, pp.791~803 (2018)
  9. Hummel R, "Brown tumor", Dtsch Arztebl Int, 118, pp.712~ (2021)
  10. Maanaoui M, "Osteitis fibrosa cystica von Recklinghausen", J Nephrol, 34, pp.925~926 (2021)
  11. Schwarz Y, "Rapid improvement of osteitis fibrosa cystica following parathyroidectomy", JCEM Case Rep, 1, pp.luac005~ (2022)
  12. Ramon A, "Osteitis fibrosa cystica", N Engl J Med, 382, pp.e15~ (2020)

관련 논문AI추천

Three Rare Concurrent Complications of Tertiary Hyperparathyroidism: Maxillary Brown Tumor, Uremic Leontiasis Ossea, and Hungry Bone SyndromeAlan Ali Moazzam, Alexander Hanlin Tyan, David Brain Hom, Natalie Bransky, Neena Ramesh Iyer, Praneet Mylavarapu, Ryan Orosco, Sophie Mestman Cannon대한골대사학회 · 대한골대사학회지2020 · 제27권 제3호Pathologic Fracture of the Femur in Brown Tumor Induced in Parathyroid Carcinoma: A Case Report공규민, 권용욱, 박상현, 박준호대한고관절학회 · Hip and Pelvis2016 · 제28권 제3호Benign Recurrent Primary Hyperparathyroidism After Parathyroid CarcinomaGibson Courtney E., Jeoffrey Syeda Manahil Haider, McCoy Kristin L.대한내분비외과학회 · Journal of Endocrine Surgery2022 · 제22권 제4호Parathyroid Crisis as Presentation of Atypical Parathyroid Adenoma: Two Diagnostically Challenging CasesAlexis Trejo Montes, Balcázar-Hernández Lourdes, González-Virla Baldomero, Tania Islem Gamboa Jimenéz, Vargas-Ortega Guadalupe대한골대사학회 · 대한골대사학회지2022 · 제29권 제2호말기 신부전 환자에서 이차성 부갑상선 기능 항진증과 연관하여 상악골에 발생한 갈색종의 7년간 추적 결과 1예김다함, 김원진, 이수진, 이유미, 임승길대한골다공증학회 · OSTEOPOROSIS2012 · 제10권 제2호Osteitis Fibrosa Cystica Mistaken for Malignant Disease김한수, 이자현, 정성민대한이비인후과학회 · Clinical and Experimental Otorhinolaryngology2013 · 제6권 제2호

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