Distant subcutaneous recurrence of a parathyroid carcinoma: abnormal uptakes in the 99mTc-sestamibi scan and 18F-FDG PET/CT imaging
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We report a rare case of distant subcutaneous parathyroid carcinoma recurrence. A 50‑year-old woman was referred to our hospital because of sustained hypercalcemiadespite surgical removal of a parathyroid carcinoma. A focal uptake in theupper mediastinal area was detected in a 99mTc-sestamibi scan, and 18F-fluorodeoxyglucose(FDG) positron-emission tomography (PET)/computed tomography(CT) imaging demonstrated a subcutaneous mass. She underwent tumor resection,and the pathological findings were consistent with a parathyroid carcinoma. The postoperative serum parathyroid hormone (PTH) level remained withinnormal limits. However, a new palpable solitary mass was identified in the upperportion of the left breast 1 year postoperatively. Both a 99mTc‑sestamibi scanand 18F-FDG PET/CT imaging revealed an abnormal lesion in the upper breast,and subsequent pathology reports confirmed parathyroid carcinoma metastasis. Serum PTH and calcium levels fell within normal ranges after tumor resection. Two subcutaneous recurrent lesions appeared likely due to tumor seeding duringthe previous endoscopic operation at a local hospital.
Abstract
We report a rare case of distant subcutaneous parathyroid carcinoma recurrence. A 50‑year-old woman was referred to our hospital because of sustained hypercalcemiadespite surgical removal of a parathyroid carcinoma. A focal uptake in theupper mediastinal area was detected in a 99mTc-sestamibi scan, and 18F-fluorodeoxyglucose(FDG) positron-emission tomography (PET)/computed tomography(CT) imaging demonstrated a subcutaneous mass. She underwent tumor resection,and the pathological findings were consistent with a parathyroid carcinoma. The postoperative serum parathyroid hormone (PTH) level remained withinnormal limits. However, a new palpable solitary mass was identified in the upperportion of the left breast 1 year postoperatively. Both a 99mTc‑sestamibi scanand 18F-FDG PET/CT imaging revealed an abnormal lesion in the upper breast,and subsequent pathology reports confirmed parathyroid carcinoma metastasis. Serum PTH and calcium levels fell within normal ranges after tumor resection. Two subcutaneous recurrent lesions appeared likely due to tumor seeding duringthe previous endoscopic operation at a local hospital.
참고문헌 (10)
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