Benign Recurrent Primary Hyperparathyroidism After Parathyroid Carcinoma

Abstract

This report describes the rare occurrence of a parathyroid adenoma 15 years after the resection of a right-sided parathyroid carcinoma, with recurrence of clinical manifestations of hyperparathyroidism. We report the case of a 41-year-old female who returned to the clinic with bone pain, memory difficulties and fatigue. After a thorough assessment, a hyperechoic nodule of parathyroid origin was detected and resected. The resected lesion was located inferior to the left thyroid lobe, measuring 1.3×0.7×0.6 cm and weighing 602 mg; histopathology was consistent with a parathyroid adenoma. Recurrent primary hyperparathyroidism due to benign adenoma, after prior surgery for parathyroid carcinoma, is a rare phenomenon. Early recognition, diagnosis and intervention are essential to prevent and/or reduce associated morbidity and mortality.