Which Neural Tract Plays a Major Role in Memory Impairment After Multiple Cerebral Infarcts? A Case Report
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Injury to the thalamocortical tract (one in the Papez circuit) that leads to memory impairment following brain injury is very rare. In this study, we present a case of partial injury to the thalamocortical tract that causes memory impairment after concurrent thalamic and hippocampal infarct. A 20-year-old male complained of memory impairment 1 month after partial injury to the thalamocortical tract. Using a probabilistic diffusing tensor tractography, it was found that the right thalamocortical tract was thinner than the left thalamocortical tract. However, all other neural tracts including the fornix, cingulum, and mammillothalamic tract were intact on both hemispheres. Therefore, the memory impairment in this patient was considered as being due to thalamic infarct based on the observation that the fornix from hippocampal infarct was intact. This case suggests that the assessment of lesions in the neural tracts of the Papez circuit might be useful for understanding the mechanism of memory impairment following cerebral infarction.
Abstract
Injury to the thalamocortical tract (one in the Papez circuit) that leads to memory impairment following brain injury is very rare. In this study, we present a case of partial injury to the thalamocortical tract that causes memory impairment after concurrent thalamic and hippocampal infarct. A 20-year-old male complained of memory impairment 1 month after partial injury to the thalamocortical tract. Using a probabilistic diffusing tensor tractography, it was found that the right thalamocortical tract was thinner than the left thalamocortical tract. However, all other neural tracts including the fornix, cingulum, and mammillothalamic tract were intact on both hemispheres. Therefore, the memory impairment in this patient was considered as being due to thalamic infarct based on the observation that the fornix from hippocampal infarct was intact. This case suggests that the assessment of lesions in the neural tracts of the Papez circuit might be useful for understanding the mechanism of memory impairment following cerebral infarction.
참고문헌 (10)
- Snaphaan L, "Poststroke memory function in nondemented patients: a systematic review on frequency and neuroimaging correlates", Stroke, 38, pp.198~203 (2007)[DOI]
- Kumral E, "Isolated hippocampal infarcts: vascular and neuropsychological findings", J Neurol Sci, 356, pp.83~89 (2015)[DOI]
- Carlesimo GA, "Vascular thalamic amnesia: a reappraisal", Neuropsychologia, 49, pp.777~789 (2011)[DOI]
- Mori S, "In vivo magnetic resonance imaging of the human limbic white matter", Front Aging Neurosci, 6, pp.321~ (2014)
- Jang SH, "Diffuse injury of the Papez circuit by focal head trauma: a diffusion tensor tractography study", Acta Neurol Belg, 117, pp.389~391 (2017)[DOI]
- Chang MC, "Diffusion tensor tractography in a patient with memory impairment following encephalitis", Acta Neurol Belg, 116, pp.629~631 (2016)[DOI]
- Jang SH, "Injury of the Papez circuit in a patient with provoked confabulation following subarachnoid hemorrhage: a diffusion tensor tractography study", Acta Neurol Belg, 116, pp.655~658 (2016)[DOI]
- Yang DS, "Injury of the thalamocingulate tract in the papez circuit in patients with mild traumatic brain injury", Am J Phys Med Rehabil, 95, pp.e34~e38 (2016)[DOI]
- Kwon HG, "Is thalamocortical tract injury responsible for memory impairment in a patient with putaminal hemorrhage?", Neural Regen Res, 10, pp.321~322 (2015)[DOI]
- Kwon HG, "Injury of the mammillothalamic tract in patients with thalamic hemorrhage", Front Hum Neurosci, 8, pp.259~ (2014)