Sex difference in bowel preparation quality and colonoscopy time
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Background/Aims: The length of colon is known to be longer in females than in males. In addition, the morphology of colon cancer is different between males and females. The aim of this study was to investigate sex differences in Boston bowel preparation score (BBPS) and colonoscopy insertion time. Methods: This study retrospectively analyzed medical records and colonoscopy readings of subjects who underwent colonoscopy at Seoul National University Bundang Hospital from March 2015 to April 2018. BPPS was used to evaluate the degree of colon cleanness before colonoscopy. Statistical analysis was performed to compare demographic, clinical, and outcome variables between two groups. Results: The study group consisted of a total of 12,561 patients (6,148 females and 6,413 males). Mean age was 57.8 ± 13.5 years for females and 57.5 ± 13.8 years for males (p = 0.695). Females showed better bowel preparation than males (mean total score: 7.4 ± 1.8 vs. 7.2 ± 1.9, p = 0.001; total score ≥ 6: 5,340 [86.9%] vs. 5,437 [84.8%], p = 0.001; BBPS ≥ 2 for all segments: 5,048 [82.1%] vs. 5,097 [79.5%], p < 0.001). However, cecal intubation time (8.3 ± 6.2 minutes vs. 6.2 ± 6.1 minutes, p < 0.001) and withdrawal time (7.9 ± 3.5 minutes vs. 7.4 ± 3.1 minutes, p < 0.001) were longer in males. Conclusions: There were sex differences in BBPS, cecal intubation time, and withdrawal time for subjects undergoing colonoscopy.
Abstract
Background/Aims: The length of colon is known to be longer in females than in males. In addition, the morphology of colon cancer is different between males and females. The aim of this study was to investigate sex differences in Boston bowel preparation score (BBPS) and colonoscopy insertion time. Methods: This study retrospectively analyzed medical records and colonoscopy readings of subjects who underwent colonoscopy at Seoul National University Bundang Hospital from March 2015 to April 2018. BPPS was used to evaluate the degree of colon cleanness before colonoscopy. Statistical analysis was performed to compare demographic, clinical, and outcome variables between two groups. Results: The study group consisted of a total of 12,561 patients (6,148 females and 6,413 males). Mean age was 57.8 ± 13.5 years for females and 57.5 ± 13.8 years for males (p = 0.695). Females showed better bowel preparation than males (mean total score: 7.4 ± 1.8 vs. 7.2 ± 1.9, p = 0.001; total score ≥ 6: 5,340 [86.9%] vs. 5,437 [84.8%], p = 0.001; BBPS ≥ 2 for all segments: 5,048 [82.1%] vs. 5,097 [79.5%], p < 0.001). However, cecal intubation time (8.3 ± 6.2 minutes vs. 6.2 ± 6.1 minutes, p < 0.001) and withdrawal time (7.9 ± 3.5 minutes vs. 7.4 ± 3.1 minutes, p < 0.001) were longer in males. Conclusions: There were sex differences in BBPS, cecal intubation time, and withdrawal time for subjects undergoing colonoscopy.
참고문헌 (40)
- Ferlay J, "Estimates of worldwide burden of cancer in 2008 : GLOBOCAN 2008", Int J Cancer, 127, pp.2893~2917 (2010)
- Ferlay J, "Cancer incidence and mortality worldwide : sources, methods and major patterns in GLOBOCAN 2012", Int J Cancer, 136, pp.E359~E386 (2015)
- 정규원, "Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2015", Cancer Research and Treatment, 50(2), pp.303~316 (2018), 대한암학회
- Kim SE, "Sexand gender-specific disparities in colorectal cancer risk", World J Gastroenterol, 21, pp.5167~5175 (2015)
- Brenner H, "Colorectal cancer", Lancet, 383, pp.1490~1502 (2014)
- Iacopetta B, "Are there two sides to colorectal cancer?", Int J Cancer, 101, pp.403~408 (2002)
- Benedix F, "Comparison of 17, 641patients with right-and left-sided colon cancer : differences in epidemiology, perioperative course, histology, and survival", Dis Colon Rectum, 53, pp.57~64 (2010)
- Kaku E, "Proportion of flat-and depressed-type and laterally spreading tumor among advanced colorectal neoplasia", Clin Gastroenterol Hepatol, 9, pp.503~508 (2011)
- Parra-Blanco A, "Achieving the best bowel preparation for colonoscopy", World J Gastroenterol, 20, pp.17709~17726 (2014)
- Rex DK, "Quality indicators for colonoscopy", Gastrointest Endosc, 81, pp.31~53 (2015)
- Serper M, "Patient factors that affect quality of colonoscopy preparation", Clin Gastroenterol Hepatol, 12, pp.451~457 (2014)
- Gandhi K, "Patient characteristics associated with quality of colonoscopy preparation : a systematic review and meta-analysis", Clin Gastroenterol Hepatol, 16, pp.357~369 (2018)
- Ness RM, "Predictors of inadequate bowel preparation for colonoscopy", Am J Gastroenterol, 96, pp.1797~1802 (2001)
- Saunders BP, "Why is colonoscopy more difficult in women?", Gastrointest Endosc, 43, pp.124~126 (1996)
- Khashab MA, "Colorectal anatomy in adults at computed tomography colonography : normal distribution and the effect of age, sex, and body mass index", Endoscopy, 41, pp.674~678 (2009)
- 유수영, "Seoul National University Bundang Hospital’s Electronic System for Total Care", Healthcare Informatics Research, 18(2), pp.145~152 (2012), 대한의료정보학회[DOI]
- Aronchick CA, "Bowel preparation scale", Gastrointest Endosc, 60, pp.1037~1038 (2004)
- Rostom A, "Validation of a new scale for the assessment of bowel preparation quality", Gastrointest Endosc, 59, pp.482~486 (2004)
- Kastenberg D, "Bowel preparation quality scales for colonoscopy", World J Gastroenterol, 24, pp.2833~2843 (2018)
- Parmar R, "Validated scales for colon cleansing : a systematic review", Am J Gastroenterol, 111, pp.197~204 (2016)
- Calderwood AH, "Comprehensive validation of the Boston Bowel Preparation Scale", Gastrointest Endosc, 72, pp.686~692 (2010)
- Clark BT, "Quantification of adequate bowel preparation for screening or surveillance colonoscopy in men", Gastroenterology, 150, pp.396~405 (2016)
- Lai EJ, "The Boston bowel preparation scale : a valid and reliable instrument for colonoscopy-oriented research", Gastrointest Endosc, 69, pp.620~625 (2009)
- Kilminster S, "Women in medicine : is there a problem? A literature review of the changing gender composition, structures and occupational cultures in medicine", Med Educ, 41, pp.39~49 (2007)
- Menon R, "Diet complexity and estrogen receptor β status affect the composition of the murine intestinal microbiota", Appl Environ Microbiol, 79, pp.5763~5773 (2013)
- Jin Joo Kim, "Comparison of Tight Junction Protein-Related Gene mRNA Expression Levels between Male and Female Gastroesophageal Reflux Disease Patients", Gut and Liver, 12(4), pp.411~419 (2018), 거트앤리버 소화기연관학회협의회
- Kotake K, "Gender differences in colorectal cancer survival in Japan", Int J Clin Oncol, 21, pp.194~203 (2016)
- Zheng B, "Gender disparity in hepatocellular carcinoma(HCC) : multiple underlying mechanisms", Sci China Life Sci, 60, pp.575~584 (2017)
- Kang Y, "Gender differences in factors associated with colorectal cancer screening : a national cross-sectional study in Korea", Asia Pac J Public Health, 29, pp.495~505 (2017)
- Din NU, "Age and gender variations in cancer diagnostic intervals in 15 cancers : analysis of data from the UK clinical practice research datalink", PLoS One, 10, pp.e0127717~ (2015)
- Rotondano G, "Quality of bowel cleansing in hospitalized patients undergoing colonoscopy : a multicenter prospective regional study", Dig Liver Dis, 47, pp.669~674 (2015)
- Akere A, "Complete colonoscopy : impact of patients’ demographics and anthropometry on caecal intubation time", BMJ Open Gastroenterol, 3, pp.e000076~ (2016)
- 정재일, "Learning Curves for Colonoscopy: A Prospective Evaluation of Gastroenterology Fellows at a Single Center", Gut and Liver, 4(1), pp.31~35 (2010), 거트앤리버 소화기연관학회협의회
- Faigel DO, "The London OMED position statement for credentialing and quality assurance in digestive endoscopy", Endoscopy, 41, pp.1069~1074 (2009)
- 이정원, "대장내시경 전처치 4 L Polyethylene Glycol 단독요법과 2 L Polyethylene Glycol 및 Sodium Phosphate 용액 병합요법 비교", 대한소화기학회지, 56(5), pp.299~306 (2010), 대한소화기학회
- 조소영, "대장내시경 전처치를 위한 4 L Polyethylene Glycol 단독요법, 4 L Polyethylene Glycol 분할요법 및 2 L Polyethylene Glycol과 Sodium Phosphate 용액 병합요법 비교", 대한소화기학회지, 59(6), pp.414~422 (2012), 대한소화기학회[DOI]
- Ell C, "Randomized trial of low-volume PEG solution versus standard PEG + electrolytes for bowel cleansing before colonoscopy", Am J Gastroenterol, 103, pp.883~893 (2008)
- Kelly NM, "A prospective audit of the efficacy, safety, and acceptability of low-volume polyethylene glycol(2 L)versus standard volume polyethylene glycol(4 L)versus magnesium citrate plus stimulant laxative as bowel preparation for colonoscopy", J Clin Gastroenterol, 46, pp.595~601 (2012)
- Valiante F, "A randomized controlled trial evaluating a new 2-L PEG solution plus ascorbic acid vs 4-L PEG for bowel cleansing prior to colonoscopy", Dig Liver Dis, 44, pp.224~227 (2012)
- Corporaal S, "Low-volume PEG plus ascorbic acid versus high-volume PEG as bowel preparation for colonoscopy", Scand J Gastroenterol, 45, pp.1380~1386 (2010)
