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2020 Korean guidelines for the management of metastatic prostate cancer

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In 2017, Korean Society of Medical Oncology (KSMO) published the Korean management guideline of metastatic prostate cancer. This paper is the 2nd edition of the Korean management guideline of metastatic prostate cancer. We updated recent many changes of management in metastatic prostate cancer in this 2nd edition guideline. The present guideline consists of the three categories: management of metastatic hormone sensitive prostate cancer; management of metastatic castration resistant prostate cancer; and clinical consideration for treating patients with metastatic prostate cancer. In category 1 and 2, levels of evidence (LEs) have been mentioned according to the general principles of evidence-based medicine. And grades of recommendation (GR) was taken into account the quality of evidence, the balance between desirable and undesirable effects, the values and preferences, and the use of resources and GR were divided into strong recommendations (SR) and weak recommendations (WR). A total of 16 key questions are selected. And we proposed recommendations and described key evidence for each recommendation. The treatment landscape of metastatic prostate cancer is changing very rapid and many trials are ongoing. To verify the results of the future trials is necessary and should be applied to the treatment for metastatic prostate cancer patients in the clinical practice. Especially, many prostate cancer patients are old age, have multiple underlying medical comorbidities, clinicians should be aware of the significance of medical management as well as clinical efficacy of systemic treatment.

Abstract

In 2017, Korean Society of Medical Oncology (KSMO) published the Korean management guideline of metastatic prostate cancer. This paper is the 2nd edition of the Korean management guideline of metastatic prostate cancer. We updated recent many changes of management in metastatic prostate cancer in this 2nd edition guideline. The present guideline consists of the three categories: management of metastatic hormone sensitive prostate cancer; management of metastatic castration resistant prostate cancer; and clinical consideration for treating patients with metastatic prostate cancer. In category 1 and 2, levels of evidence (LEs) have been mentioned according to the general principles of evidence-based medicine. And grades of recommendation (GR) was taken into account the quality of evidence, the balance between desirable and undesirable effects, the values and preferences, and the use of resources and GR were divided into strong recommendations (SR) and weak recommendations (WR). A total of 16 key questions are selected. And we proposed recommendations and described key evidence for each recommendation. The treatment landscape of metastatic prostate cancer is changing very rapid and many trials are ongoing. To verify the results of the future trials is necessary and should be applied to the treatment for metastatic prostate cancer patients in the clinical practice. Especially, many prostate cancer patients are old age, have multiple underlying medical comorbidities, clinicians should be aware of the significance of medical management as well as clinical efficacy of systemic treatment.

참고문헌 (132)

  1. "Levels of evidence (March 2009)" (2009)[URL]
  2. Guyatt GH, "GRADE : an emerging consensus on rating quality of evidence and strength of recommendations", BMJ, 336, pp.924~926 (2008)
  3. Morris MJ, "Optimizing anticancer therapy in metastatic non-castrateprostate cancer : American Society of Clinical Oncology clinical practice guideline", J Clin Oncol, 36, pp.1521~1539 (2018)
  4. "Prostate cancer (Version 2.2019)" (2019)[URL]
  5. Cornfford P, "EAU-ESTRO-SIOG guidelines on prostate cancer. Part II : treatment of relapsing, metastatic, and castration-resistant prostate cancer", Eur Urol, 71, pp.630~642 (2017)
  6. Parker C, "Cancer of the prostate: ESMO clinical practice guidelines for diagnosis, treatment and follow-up", Ann Oncol, 26(Suppl 5), pp.v69~v77 (2015)
  7. Samson DJ, "Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma", Cancer, 95, pp.361~376 (2002)
  8. Trachtenberg J, "A phase 3, multicenter, open label, randomized study of abarelix versus leuprolide plus daily antiandrogen in men with prostate cancer", J Urol, 167, pp.1670~1674 (2002)
  9. Klotz L, "The efficacy and safety of degarelix : a 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer", BJU Int, 102, pp.1531~1538 (2008)
  10. Gravis G, "Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer(GETUG-AFU 15) : a randomised, open-label, phase 3 trial", Lancet Oncol, 14, pp.149~158 (2013)
  11. Sweeney CJ, "Chemohormonal therapy in metastatic hormone-sensitive prostate cancer", N Engl J Med, 373, pp.737~746 (2015)
  12. James ND, "Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer(STAMPEDE) : survival results from an adaptive, multiarm, multistage, platform randomised controlled trial", Lancet, 387, pp.1163~1177 (2016)
  13. Kyriakopoulos CE, "Chemohormonal therapy in metastatic hormone-sensitive prostate cancer : long-term survival analysis of the randomized phase III E3805 CHAARTED trial", J Clin Oncol, 36, pp.1080~1087 (2018)
  14. Clarke NW, "Addition of docetaxel to hormonal therapy in low-and high-burden metastatic hormone sensitive prostate cancer : long-term survival results from the STAMPEDE trial", Ann Oncol, 30, pp.1992~2003 (2019)
  15. Gravis G, "Androgen deprivation therapy(ADT)plus docetaxel versus ADT alone in metastatic non castrate prostate cancer : impact of metastatic burden and long-term survival analysis of the randomized phase 3 GETUG-AFU15 trial", Eur Urol, 70, pp.256~262 (2016)
  16. Tucci M, "Addition of docetaxel to androgen deprivation therapy for patients with hormone-sensitive metastatic prostate cancer : a systematic review and meta-analysis", Eur Urol, 69, pp.563~573 (2016)
  17. Vale CL, "Addition of docetaxel or bisphosphonates to standard of care in men with localised or metastatic, hormone-sensitive prostate cancer : a systematic review and meta-analyses of aggregate data", Lancet Oncol, 17, pp.243~256 (2016)
  18. Attard G, "Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer", BJU Int, 96, pp.1241~1246 (2005)
  19. Tran C, "Development of a second-generation antiandrogen for treatment of advanced prostate cancer", Science, 324, pp.787~790 (2009)
  20. Clegg NJ, "ARN-509 : a novel antiandrogen for prostate cancer treatment", Cancer Res, 72, pp.1494~1503 (2012)
  21. Fizazi K, "Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer", N Engl J Med, 377, pp.352~360 (2017)
  22. Fizazi K, "Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer(LATITUDE) : final overall survival analysis of a randomised, double-blind, phase 3 trial", Lancet Oncol, 20, pp.686~700 (2019)
  23. James ND, "Abiraterone for prostate cancer not previously treated with hormone therapy", N Engl J Med, 377, pp.338~351 (2017)
  24. Hoyle AP, "Abiraterone in"high-"and"low-risk"metastatic hormone-sensitive prostate cancer", Eur Urol, 76, pp.719~728 (2019)
  25. Davis ID, "Enzalutamide with standard first-line therapy in metastatic prostate cancer", N Engl J Med, 381, pp.121~131 (2019)
  26. Armstrong AJ, "ARCHES : a randomized, phase III study of androgen deprivation therapy with enzalutamide or placebo in men with metastatic hormone-sensitive prostate cancer", J Clin Oncol, 37, pp.2974~2986 (2019)
  27. Chi KN, "Apalutamide for metastatic, castration-sensitive prostate cancer", N Engl J Med, 381, pp.13~24 (2019)
  28. Studer UE, "Immediate or deferred androgen deprivation for patients with prostate cancer not suitable for local treatment with curative intent : European Organisation for Research and Treatment of Cancer(EORTC)Trial 30891", J Clin Oncol, 24, pp.1868~1876 (2006)
  29. Kirk D, "Timing and choice of androgen ablation", Prostate Cancer Prostatic Dis, 7, pp.217~222 (2004)
  30. Studer UE, "Immediate versus deferred hormonal treatment for patients with prostate cancer who are not suitable for curative local treatment : results of the randomized trial SAKK 08", 88, 2004, pp.22, 4109~4118
  31. Scher HI, "Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone : recommendations of the Prostate Cancer Clinical Trials Working Group", J Clin Oncol, 26, pp.1148~1159 (2008)
  32. Eisenhauer EA, "New response evaluation criteria in solid tumours : revised RECIST guideline(version 1. 1)", Eur J Cancer, 45, pp.228~247 (2009)
  33. Schwartz LH, "RECIST 1. 1. Standardisation and disease-specific adaptations : perspectives from the RECIST Working Group", Eur J Cancer, 62, pp.138~145 (2016)
  34. Leone G, "Antiandrogen withdrawal syndrome(AAWS)in the treatment of patients with prostate cancer", Endocr Relat Cancer, 25, pp.R1~R9 (2018)
  35. Ryan CJ, "Abiraterone in metastatic prostate cancer without previous chemotherapy", N Engl J Med, 368, pp.138~148 (2013)
  36. Basch E, "Abiraterone acetate plus prednisone versus prednisone alone in chemotherapy-naive men with metastatic castration-resistant prostate cancer : patient-reported outcome results of a randomised phase 3 trial", Lancet Oncol, 14, pp.1193~1199 (2013)
  37. Beer TM, "Enzalutamide in metastatic prostate cancer before chemotherapy", N Engl J Med, 371, pp.424~433 (2014)
  38. de Bono JS, "Abiraterone and increased survival in metastatic prostate cancer", N Engl J Med, 364, pp.1995~2005 (2011)
  39. Fizazi K, "Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer : final overall survival analysis of the COU-AA-301randomised, double-blind, placebo-controlled phase 3study", Lancet Oncol, 13, pp.983~992 (2012)
  40. Scher HI, "Increased survival with enzalutamide in prostate cancer after chemotherapy", N Engl J Med, 367, pp.1187~1197 (2012)
  41. Graff JN, "Efficacy and safety of enzalutamide in patients 75 years or older with chemotherapy-naive metastatic castration-resistant prostate cancer : results from PREVAIL", Ann Oncol, 27, pp.286~294 (2016)
  42. Tannock IF, "Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer", N Engl J Med, 351, pp.1502~1512 (2004)
  43. Berthold DR, "Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer : updated survival in the TAX 327 study", J Clin Oncol, 26, pp.242~245 (2008)
  44. Kellokumpu-Lehtinen PL, "2-Weekly versus 3-weekly docetaxel to treat castration-resistant advanced prostate cancer : a randomised, phase 3 trial", Lancet Oncol, 14, pp.117~124 (2013)
  45. de Bono JS, "Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment : a randomised open-label trial", Lancet, 376, pp.1147~1154 (2010)
  46. Eisenberger M, "Phase III study comparing a reduced dose of cabazitaxel(20 mg", m 2)and the currently approved dose(25 mg, J Clin Oncol, pp.2017, 35[DOI]
  47. Oudard S, "Cabazitaxel versus docetaxel as first-line therapy for patients with metastatic castration-resistant prostate cancer : a randomized phase III trial-FIRSTANA", J Clin Oncol, 35, pp.3189~3197 (2017)
  48. de Wit R, "Cabazitaxel versus abiraterone or enzalutamide in metastatic prostate cancer", N Engl J Med, 381, pp.2506~2518 (2019)
  49. Parker C, "Alpha emitter radium-223 and survival in metastatic prostate cancer", N Engl J Med, 369, pp.213~223 (2013)
  50. Smith M, "Addition of radium-223to abiraterone acetate and prednisone or prednisolone in patients with castration-resistant prostate cancer and bone metastases(ERA 223) : a randomised, double-blind, placebo-controlled, phase 3 trial", Lancet Oncol, 20, pp.408~419 (2019)
  51. Mullane SA, "Precision medicine for advanced prostate cancer", Curr Opin Urol, 26, pp.231~239 (2016)
  52. Cancer Genome Atlas Research Network, "The molecular taxonomy of primary prostate cancer", Cell, 163, pp.1011~1125 (2015)
  53. Castro E, "Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer", J Clin Oncol, 31, pp.1748~1757 (2013)
  54. Mateo J, "DNA repair in prostate cancer : biology and clinical implications", Eur Urol, 71, pp.417~425 (2017)
  55. Mateo J, "DNA-repair defects and olaparib in metastatic prostate cancer", N Engl J Med, 373, pp.1697~1708 (2015)
  56. Mateo J, "Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations(TOPARP-B) : a multicentre, open-label, randomised, phase 2 trial", Lancet Oncol, 21, pp.162~174 (2020)
  57. de Bono J, "Olaparib for metastatic castration-resistant prostate cancer", N Engl J Med, 382, pp.2091~2102 (2020)
  58. Beer TM, "Randomized, double-blind, phase III trial of ipilimumab versus placebo in asymptomatic or minimally symptomatic patients with metastatic chemotherapy-naive castration-resistant prostate cancer", J Clin Oncol, 35, pp.40~47 (2017)
  59. Hansen AR, "Pembrolizumab for advanced prostate adenocarcinoma : findings of the KEYNOTE-028 study", Ann Oncol, 29, pp.1807~1813 (2018)
  60. Antonarakis ES, "Pembrolizumab for treatment-refractory metastatic castration-resistant prostate cancer : multicohort, open-label phase II KEYNOTE-199 study", J Clin Oncol, 38, pp.395~405 (2020)
  61. El-Amm J, "The current landscape of treatment in non-metastatic castration-resistant prostate cancer", Clin Med Insights Oncol, 13, pp.1179554919833927~ (2019)
  62. Smith MR, "Denosumab and bone metastasis-free survival in men with nonmetastatic castration-resistant prostate cancer : exploratory analyses by baseline prostate-specific antigen doubling time", J Clin Oncol, 31, pp.3800~3806 (2013)
  63. Smith MR, "Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer", J Clin Oncol, 23, pp.2918~2925 (2005)
  64. Smith MR, "Apalutamide treatment and metastasis-free survival in prostate cancer", N Engl J Med, 378, pp.1408~1418 (2018)
  65. Hussain M, "Enzalutamide in men with nonmetastatic, castration-resistant prostate cancer", N Engl J Med, 378, pp.2465~2474 (2018)
  66. Fizazi K, "Darolutamide in nonmetastatic, castration-resistant prostate cancer", N Engl J Med, 380, pp.1235~1246 (2019)
  67. de Morree ES, "Association of survival benefit with docetaxel in prostate cancer and total number of cycles administered : a post hoc analysis of the mainsail study", JAMA Oncol, 3, pp.68~75 (2017)
  68. de Bono JS, "Subsequent chemotherapy and treatment patterns after abiraterone acetate in patients with metastatic castration-resistant prostate cancer : post hoc analysis of COU-AA-302", Eur Urol, 71, pp.656~664 (2017)
  69. Khalaf DJ, "Optimal sequencing of enzalutamide and abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer : a multicentre, randomised, open-label, phase 2, crossover trial", Lancet Oncol, 20, pp.1730~1739 (2019)
  70. Lavaud P, "Anticancer activity and tolerance of treatments received beyond progression in men treated upfront with androgen deprivation therapy with or without docetaxel for metastatic castration-naive prostate cancer in the GETUG-AFU 15 phase 3 trial", Eur Urol, 73, pp.696~703 (2018)
  71. Mountzios I, "Intermittent docetaxel chemotherapy in patients with castrate-resistant prostate cancer", Urology, 77, pp.682~687 (2011)
  72. Caffo O, "Multiple rechallenges for castration-resistant prostate cancer patients responding to first-line docetaxel : assessment of clinical outcomes and predictive factors", Urology, 79, pp.644~649 (2012)
  73. Di Lorenzo G, "Phase II study of docetaxel re-treatment in docetaxel-pretreated castration-resistant prostate cancer", BJU Int, 107, pp.234~239 (2011)
  74. Scher HI, "Prostate cancer clinical trial end points : "RECIST"ing a step backwards", Clin Cancer Res, 11, pp.5223~5232 (2005)
  75. Saad F, "A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma", J Natl Cancer Inst, 94, pp.1458~1468 (2002)
  76. Saad F, "Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer", J Natl Cancer Inst, 96, pp.879~882 (2004)
  77. Small EJ, "Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer", J Clin Oncol, 21, pp.4277~4284 (2003)
  78. Ernst DS, "Randomized, double-blind, controlled trial of mitoxantrone", prednisone and clodronate versus mitoxantrone, J Clin Oncol, pp.2003, 21[DOI]
  79. Fizazi K, "Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer : a randomised, double-blind study", Lancet, 377, pp.813~822 (2011)
  80. Smith MR, "Randomized controlled trial of early zoledronic acid in men with castration-sensitive prostate cancer and bone metastases : results of CALGB 90202(alliance)", J Clin Oncol, 32, pp.1143~1150 (2014)
  81. Kamba T, "A phase III multicenter, randomized, controlled study of combined androgen blockade with versus without zoledronic acid in prostate cancer patients with metastatic bone disease : results of the ZAPCA trial", Int J Clin Oncol, 22, pp.166~173 (2017)
  82. Droz JP, "Management of prostate cancer in older patients : updated recommendations of a working group of the International Society of Geriatric Oncology", Lancet Oncol, 15, pp.e404~e414 (2014)
  83. Horwich A, "Prostate cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up", Ann Oncol, 24(Suppl 6), pp.vi106~vi114 (2013)
  84. Body JJ, "Hypocalcaemia in patients with metastatic bone disease treated with denosumab", Eur J Cancer, 51, pp.1812~1821 (2015)
  85. Bienz M, "Androgen-deprivation therapy and bone loss in prostate cancer patients : a clinical review", Bonekey Rep, 4, pp.716~ (2015)
  86. Smith MR, "Risk of clinical fractures after gonadotropin-releasing hormone agonist therapy for prostate cancer", J Urol, 175, pp.136~139 (2006)
  87. Shahinian VB, "Risk of fracture after androgen deprivation for prostate cancer", N Engl J Med, 352, pp.154~164 (2005)
  88. Michaelson MD, "Randomized controlled trial of annual zoledronic acid to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer", J Clin Oncol, 25, pp.1038~1042 (2007)
  89. Greenspan SL, "Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer : a randomized trial", Ann Intern Med, 146, pp.416~424 (2007)
  90. Smith MR, "Denosumab in men receiving androgen-deprivation therapy for prostate cancer", N Engl J Med, 361, pp.745~755 (2009)
  91. Lutz S, "The role of radiation therapy in controlling painful bone metastases", Curr Pain Headache Rep, 16, pp.300~306 (2012)
  92. Goblirsch MJ, "Biology of bone cancer pain", Clin Cancer Res, 12, pp.6231s~6235s (2006)
  93. Vakaet LA, "Pain control by ionizing radiation of bone metastasis", Int J Dev Biol, 48, pp.599~606 (2004)
  94. Hartsell WF, "Randomized trial of short-versus long-course radiotherapy for palliation of painful bone metastases", J Natl Cancer Inst, 97, pp.798~804 (2005)
  95. Chow E, "Single versus multiple fractions of repeat radiation for painful bone metastases : a randomised, controlled, non-inferiority trial", Lancet Oncol, 15, pp.164~171 (2014)
  96. Chow E, "Update on the systematic review of palliative radiotherapy trials for bone metastases", Clin Oncol(R Coll Radiol), 24, pp.112~124 (2012)
  97. Huisman M, "Effectiveness of reirradiation for painful bone metastases : a systematic review and meta-analysis", Int J Radiat Oncol Biol Phys, 84, pp.8~14 (2012)
  98. Holzbeierlein JM, "Complications of androgen deprivation therapy for prostate cancer", Curr Opin Urol, 14, pp.177~183 (2004)
  99. Elliott S, "Androgen deprivation therapy for prostate cancer : recommendations to improve patient and partner quality of life", J Sex Med, 7, pp.2996~3010 (2010)
  100. de Voogt HJ, "Cardiovascular side effects of diethylstilbestrol, cyproterone acetate, medroxyprogesterone acetate and estramustine phosphate used for the treatment of advanced prostatic cancer : results from European Organization for Research on Treatment of Cancer trials 30761 and 30762", J Urol, 135, pp.303~307 (1986)
  101. Tunio MA, "Optimal prophylactic and definitive therapy for bicalutamide-induced gynecomastia : results of a meta-analysis", Curr Oncol, 19, pp.e280~e288 (2012)
  102. Viani GA, "Prevention of gynecomastia and breast pain caused by androgen deprivation therapy in prostate cancer: tamoxifen or radiotherapy?", Int J Radiat Oncol Biol Phys, 83, pp.e519~e524 (2012)
  103. Lu-Yao G, "Changing patterns in competing causes of death in men with prostate cancer : a population based study", J Urol, 171, pp.2285~2290 (2004)
  104. O’Farrell S, "Risk and timing of cardiovascular disease after androgen-deprivation therapy in men with prostate cancer", J Clin Oncol, 33, pp.1243~1251 (2015)
  105. Saigal CS, "Androgen deprivation therapy increases cardiovascular morbidity in men with prostate cancer", Cancer, 110, pp.1493~1500 (2007)
  106. Bosco C, "Quantifying observational evidence for risk of fatal and nonfatal cardiovascular disease following androgen deprivation therapy for prostate cancer : a meta-analysis", Eur Urol, 68, pp.386~396 (2015)
  107. Keating NL, "Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer", J Clin Oncol, 24, pp.4448~4456 (2006)
  108. D’Amico AV, "Influence of androgen suppression therapy for prostate cancer on the frequency and timing of fatal myocardial infarctions", J Clin Oncol, 25, pp.2420~2425 (2007)
  109. Efstathiou JA, "Cardiovascular mortality after androgen deprivation therapy for locally advanced prostate cancer : RTOG 85-31", J Clin Oncol, 27, pp.92~99 (2009)
  110. Nguyen PL, "Association of androgen deprivation therapy with cardiovascular death in patients with prostate cancer : a meta-analysis of randomized trials", JAMA, 306, pp.2359~2366 (2011)
  111. Roach M 3rd, "Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer : longterm results of RTOG 8610", J Clin Oncol, 26, pp.585~591 (2008)
  112. Tsai HK, "Androgen deprivation therapy for localized prostate cancer and the risk of cardiovascular mortality", J Natl Cancer Inst, 99, pp.1516~1524 (2007)
  113. Voog JC, "Cardiovascular mortality following short-term androgen deprivation in clinically localized prostate cancer : an analysis of RTOG 94-08", Eur Urol, 69, pp.204~210 (2016)
  114. Wilcox C, "Androgen deprivation therapy for prostate cancer does not increase cardiovascular mortality in the long term", Oncology, 82, pp.56~58 (2012)
  115. D’Amico AV, "Long-term follow-up of a randomized trial of radiation with or without androgen deprivation therapy for localized prostate cancer", JAMA, 314, pp.1291~1293 (2015)
  116. Levine GN, "Androgen-deprivation therapy in prostate cancer and cardiovascular risk : a science advisory from the American Heart Association, American Cancer Society, and American Urological Association : endorsed by the American Society for Radiation Oncology", Circulation, 121, pp.833~840 (2010)
  117. Guan J, "Cardiology patient page : ABCDE steps for heart and vascular wellness following a prostate cancer diagnosis", Circulation, 132, pp.e218~e220 (2015)
  118. Shahinian VB, "Risk of the"androgen deprivation syndrome"in men receiving androgen deprivation for prostate cancer", Arch Intern Med, 166, pp.465~471 (2006)
  119. Nead KT, "Association between androgen deprivation therapy and risk of dementia", JAMA Oncol, 3, pp.49~55 (2017)
  120. Alibhai SM, "Impact of androgen-deprivation therapy on cognitive function in men with nonmetastatic prostate cancer", J Clin Oncol, 28, pp.5030~5037 (2010)
  121. Cherrier MM, "Testosterone supplementation improves spatial and verbal memory in healthy older men", Neurology, 57, pp.80~88 (2001)
  122. Green HJ, "Altered cognitive function in men treated for prostate cancer with luteinizing hormone-releasing hormone analogues and cyproterone acetate : a randomized controlled trial", BJU Int, 90, pp.427~432 (2002)
  123. Sun M, "Cognitive impairment in men with prostate cancer treated with androgen deprivation therapy : a systematic review and meta-analysis", J Urol, 199, pp.1417~1425 (2018)
  124. Yang J, "Dissociation of event-based prospective memory and time-based prospective memory in patients with prostate cancer receiving androgen-deprivation therapy: a neuropsychological study", Eur J Cancer Care(Engl), 24, pp.198~204 (2015)
  125. Hirano D, "Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy", Eur Urol, 45, pp.586~592 (2004)
  126. Ismail A HR, "Androgen ablation promotes neuroendocrine cell differentiation in dog and human prostate", Prostate, 51, pp.117~125 (2002)
  127. Nadal R, "Small cell carcinoma of the prostate", Nat Rev Urol, 11, pp.213~219 (2014)
  128. Wang HT, "Neuroendocrine Prostate Cancer (NEPC) progressing from conventional prostatic adenocarcinoma: factors associated with time to development of NEPC and survival from NEPC diagnosis-a systematic review and pooled analysis", J Clin Oncol, 32, pp.3383~3390 (2014)
  129. Aggarwal R, "Clinical and genomic characterization of treatment-emergent small-cell neuroendocrine prostate cancer : a multi-institutional prospective study", J Clin Oncol, 36, pp.2492~2503 (2018)
  130. Yao JL, "Small cell carcinoma of the prostate : an immunohistochemical study", Am J Surg Pathol, 30, pp.705~712 (2006)
  131. Spiess PE, "Treatment outcomes of small cell carcinoma of the prostate : a single-center study", Cancer, 110, pp.1729~1737 (2007)
  132. Corn PG, "Cabazitaxel plus carboplatin for the treatment of men with metastatic castration-resistant prostate cancers : a randomised, open-label, phase 1-2 trial", Lancet Oncol, 20, pp.1432~1443 (2019)

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