Subcortical Aphasia After Stroke
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Objective To evaluate the types and severity of subcortical aphasia after stroke and to determine the predictors of the degree of aphasic impairment.Methods Medical records of 38 patients with post-stroke subcortical aphasia (19 males; mean age, 61.7±13.8 years) were reviewed retrospectively with respect to the following tests: the Korean version of the Western Aphasia Battery (K-WAB), the Korean version of the Modified Barthel Index (K-MBI), and the Fugl-Meyer Index (FMI). The severity of aphasia was evaluated by the aphasia quotient (AQ) and the language quotient (LQ).Results Anomic aphasia was the most frequent type of aphasia (n=15, 39.5%), and the lesion most frequently observed in subcortical aphasia was located in the basal ganglia (n=19, 50.0%). Patients with lesions in the basal ganglia exhibited the lowest scores on the FMI for the upper extremities (p=0.04). Severity of aphasia was significantly correlated with the K-MBI (Pearson correlation coefficient: g=0.45, p=0.01 for AQ and g=0.53, p=0.01 for LQ) and FMI scores for the lower extremities (g=0.43, p=0.03 for AQ and g=0.49, p=0.05 for LQ). In a multivariate logistic regression analysis, K-MBI remained the only explanatory variable closely associated with aphasia severity.Conclusion This study showed the general characteristics of post-stroke subcortical aphasia, and it revealed that K-MBI was an associated and explanatory factor for aphasia severity.
Abstract
Objective To evaluate the types and severity of subcortical aphasia after stroke and to determine the predictors of the degree of aphasic impairment.Methods Medical records of 38 patients with post-stroke subcortical aphasia (19 males; mean age, 61.7±13.8 years) were reviewed retrospectively with respect to the following tests: the Korean version of the Western Aphasia Battery (K-WAB), the Korean version of the Modified Barthel Index (K-MBI), and the Fugl-Meyer Index (FMI). The severity of aphasia was evaluated by the aphasia quotient (AQ) and the language quotient (LQ).Results Anomic aphasia was the most frequent type of aphasia (n=15, 39.5%), and the lesion most frequently observed in subcortical aphasia was located in the basal ganglia (n=19, 50.0%). Patients with lesions in the basal ganglia exhibited the lowest scores on the FMI for the upper extremities (p=0.04). Severity of aphasia was significantly correlated with the K-MBI (Pearson correlation coefficient: g=0.45, p=0.01 for AQ and g=0.53, p=0.01 for LQ) and FMI scores for the lower extremities (g=0.43, p=0.03 for AQ and g=0.49, p=0.05 for LQ). In a multivariate logistic regression analysis, K-MBI remained the only explanatory variable closely associated with aphasia severity.Conclusion This study showed the general characteristics of post-stroke subcortical aphasia, and it revealed that K-MBI was an associated and explanatory factor for aphasia severity.
참고문헌 (34)
- Hillis AE, "Variability in subcortical aphasia is due to variable sites of cortical hypoperfusion", Brain Lang, 89, pp.524~530 (2004)
- Alexander MP, "Correlations of subcortical CT lesion sites and aphasia profiles", Brain, 110(Pt 4), pp.961~991 (1987)
- Murdoch BE, "Subcortical brain mechanisms in speech and language", Folia Phoniatr Logop, 53, pp.233~251 (2001)
- Choi JY, "Subcortical aphasia after striatocapsular infarction:quantitative analysis of brain perfusion SPECT using statistical parametric mapping and a statistical probabilistic anatomic map", J Nucl Med, 48, pp.194~200 (2007)
- Jensen AM, "A comparison of picture description abilities in individuals with vascular subcortical lesions and Huntington’s disease", J Commun Disord, 39, pp.62~77 (2006)
- Gout A, "Aphasia owing to subcortical brain infarcts in childhood", J Child Neurol, 20, pp.1003~1008 (2005)
- Mohr JP, "Thalamic hemorrhage and aphasia", Brain Lang, 2, pp.3~17 (1975)
- Damasio AR, "Aphasia with nonhemorrhagic lesions in the basal ganglia and internal capsule", Arch Neurol, 39, pp.15~24 (1982)
- Naeser MA, "Aphasia with predominantly subcortical lesion sites: description of three capsular", putaminal aphasia syndromes, 1982, pp.w39, 2~14
- Graff-Radford NR, "Nonhaemorrhagic thalamic infarction. Clinical, neuropsychological and electrophysiological findings in four anatomical groups defined by computerized tomography", Brain, 108(Pt 2), pp.485~516 (1985)
- Mega MS, "Subcortical aphasia: the core profile of capsulostriatal infarction", Neurology, 44, pp.1824~1829 (1994)
- Nadeau SE, "Subcortical aphasia", Brain Lang, 58, pp.355~402 (1997)
- Schaltenbrand G, "The effects on speech and language of stereotactical stimulation in thalamus and corpus callosum", Brain Lang, 2, pp.70~77 (1975)
- Staudt M, "Early left periventricular brain lesions induce right hemispheric organization of speech", Neurology, 57, pp.122~125 (2001)
- Kennedy M, "Chronic aphasia subsequent to striato-capsular and thalamic lesions in the left hemisphere", Brain Lang, 44, pp.284~295 (1993)
- Kim H, "Paradise Korean version of the Western Aphasia Battery" (2001), Paradise Welfare Foundation
- Kertesz A, "Aphasia and associated disorders: taxonomy, localization, and recovery" (1979), Grune &Stratton
- Kertesz A, "The aphasia quotient: the taxonomic approach to measurement of aphasic disability", Can J Neurol Sci, 1, pp.7~16 (1974)
- Shewan CM, "The Language Quotient (LQ): a new measure for the Western Aphasia Battery", J Commun Disord, 19, pp.427~439 (1986)
- 정한영, "한글판 수정바델지수(K-MBI)의 개발: 뇌졸중 환자 대상의 다기관 연구", Annals of Rehabilitation Medicine, 31(3), pp.283~297 (2007), 대한재활의학회
- Sanford J, "Reliability of the Fugl-Meyer assessment for testing motor performance in patients following stroke", Phys Ther, 73, pp.447~454 (1993)
- Williams SM, "Factor analysis of the Edinburgh Handedness Inventory", Cortex, 22, pp.325~326 (1986)
- 강은경, "Severity of Post-stroke Aphasia According to Aphasia Type and Lesion Location in Koreans", Journal of Korean Medical Science, 25(1), pp.123~127 (2010), 대한의학회
- Kim DH, "Types, severity and prognostic factors in subcortical aphasia", J Korean Acad Rehabil Med, 23, pp.478~484 (1999)
- Devinsky O, "Neurology of cognitive and behavioral disorders" (2004), Oxford University Press
- Alexander MP, "Behavioral neurology and neuropsychology", pp.133~149 (1997), McGraw-Hill
- Wade DT, "Aphasia after stroke: natural history and associated deficits", J Neurol Neurosurg Psychiatry, 49, pp.11~16 (1986)
- Kauhanen ML, "Aphasia, depression, and non-verbal cognitive impairment in ischaemic stroke", Cerebrovasc Dis, 10, pp.455~461 (2000)
- Wade DT, "Aphasia after stroke: natural history and associated deficits", J Neurol Neurosurg Psychiatry, 49, pp.11~16 (1986)
- Fang Y, "A study on additional early physiotherapy after stroke and factors affecting functional recovery", Clin Rehabil, 17, pp.608~617 (2003)
- Pedersen PM, "Aphasia after stroke:type, severity and prognosis. The Copenhagen aphasia study", Cerebrovasc Dis, 17, pp.35~43 (2004)
- Godefroy O, "Vascular aphasias: main characteristics of patients hospitalized in acute stroke units", Stroke, 33, pp.702~705 (2002)
- Kirk A, "Subcortical contributions to drawing", Brain Cogn, 21, pp.57~70 (1993)
- Weiller C, "The case of aphasia or neglect after striatocapsular infarction", Brain, 116(Pt 6), pp.1509~1525 (1993)