A New Functional Scale and Ambulatory Functional Classification of Duchenne Muscular Dystrophy: Scale Development and Preliminary Analyses of Reliability and Validity
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Objective To develop a simplified functional scale and classification system to evaluate the functional abilities of patients with Duchenne muscular dystrophy (DMD). Methods A Comprehensive Functional Scale for DMD (CFSD) was developed using the modified Delphi method. The accompanying Ambulatory Functional Classification System for DMD (AFCSD) was developed based on previously published classification systems. Results The CFSD consists of 21 items and 78 sub-items, assessing body structure and function, activities, and participation. Inter-rater intraclass correlation coefficient values were above 0.7 for 17 items. The overall limits of agreement between the two examiners ranged from -6.21 to 3.11. The Spearman correlation coefficient between the total score on the AFCSD and the Vignos Functional Scale was 0.833, and 0.714 between the total score of the AFCSD and the Brooke scale. Significant negative correlations existed between the total score for each functional level of the AFCSD and each functional grade of the Vignos and Brooke scales. The total scores of the CFSD varied significantly between the functional grades of the Vignos scale, and specific grades of the Brooke scale. For the AFCSD, total scores of the CFSD varied significantly between the functional levels. Conclusion We have developed a new scale and the associated classification system, to assess the functional ability of children diagnosed with DMD. Preliminary evaluation of the psychometric properties of the functional scale and classification systems indicate sufficient reliability and concurrent validity.
Abstract
Objective To develop a simplified functional scale and classification system to evaluate the functional abilities of patients with Duchenne muscular dystrophy (DMD). Methods A Comprehensive Functional Scale for DMD (CFSD) was developed using the modified Delphi method. The accompanying Ambulatory Functional Classification System for DMD (AFCSD) was developed based on previously published classification systems. Results The CFSD consists of 21 items and 78 sub-items, assessing body structure and function, activities, and participation. Inter-rater intraclass correlation coefficient values were above 0.7 for 17 items. The overall limits of agreement between the two examiners ranged from -6.21 to 3.11. The Spearman correlation coefficient between the total score on the AFCSD and the Vignos Functional Scale was 0.833, and 0.714 between the total score of the AFCSD and the Brooke scale. Significant negative correlations existed between the total score for each functional level of the AFCSD and each functional grade of the Vignos and Brooke scales. The total scores of the CFSD varied significantly between the functional grades of the Vignos scale, and specific grades of the Brooke scale. For the AFCSD, total scores of the CFSD varied significantly between the functional levels. Conclusion We have developed a new scale and the associated classification system, to assess the functional ability of children diagnosed with DMD. Preliminary evaluation of the psychometric properties of the functional scale and classification systems indicate sufficient reliability and concurrent validity.
참고문헌 (29)
- Moxley RT 3rd, "Change in natural history of Duchenne muscular dystrophy with long-term corticosteroid treatment: implications for management", J Child Neurol, 25, pp.1116~1129 (2010)[DOI]
- Voit T, "Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory, randomised, placebocontrolled phase 2 study", Lancet Neurol, 13, pp.987~996 (2014)[DOI]
- Seto JT, "Therapy of genetic disorders-novel therapies for Duchenne muscular dystrophy", Curr Pediatr Rep, 2, pp.102~112 (2014)[DOI]
- Bakker JP, "The effects of knee-ankle-foot orthoses in the treatment of Duchenne muscular dystrophy: review of the literature", Clin Rehabil, 14, pp.343~359 (2000)[DOI]
- Skalsky AJ, "Prevention and management of limb contractures in neuromuscular diseases", Phys Med Rehabil Clin N Am, 23, pp.675~687 (2012)[DOI]
- Sethi PK, "The Knud Jansen lecture. Technological choices in prosthetics and orthotics for developing countries", Prosthet Orthot Int, 13, pp.117~124 (1989)
- Bushby K, "Diagnosis and management of Duchenne muscular dystrophy. Part 2. Implementation of multidisciplinary care", Lancet Neurol, 9, pp.177~189 (2010)[DOI]
- Loos GP, "Probable future funding priorities in maternal and child health: a modified Delphi National Survey", J Health Polit Policy Law, 9, pp.683~693 (1985)[DOI]
- Palisano R, "Development and reliability of a system to classify gross motor function in children with cerebral palsy", Dev Med Child Neurol, 39, pp.214~223 (1997)
- Hidecker MJ, "Developing and validating the Communication Function Classification System for individuals with cerebral palsy", Dev Med Child Neurol, 53, pp.704~710 (2011)[DOI]
- Eliasson AC, "The Manual Ability Classification System (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability", Dev Med Child Neurol, 48, pp.549~554 (2006)[DOI]
- Cedarbaum JM, "The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III)", J Neurol Sci, 169, pp.13~21 (1999)[DOI]
- Mahoney FI, "Functional evaluation: the Barthel Index", Md State Med J, 14, pp.61~65 (1965)
- Hocking C, "Sensitivity of Shah, Vanclay and Cooper's modified Barthel Index", Clin Rehabil, 13, pp.141~147 (1999)[DOI]
- Lue YJ, "Development and validation of a muscular dystrophy-specific functional rating scale", Clin Rehabil, 20, pp.804~817 (2006)[DOI]
- Krosschell KJ, "A modified Hammersmith functional motor scale for use in multi-center research on spinal muscular atrophy", Neuromuscul Disord, 16, pp.417~426 (2006)[DOI]
- van den Beld WA, "A new motor performance test in a prospective study on children with suspected myopathy", Dev Med Child Neurol, 48, pp.739~743 (2006)[DOI]
- Ostensjo S, "Assessment of everyday functioning in young children with disabilities: an ICF-based analysis of concepts and content of the Pediatric Evaluation of Disability Inventory (PEDI)", Disabil Rehabil, 28, pp.489~504 (2006)[DOI]
- Brooke MH, "Clinical trial in Duchenne dystrophy. I. The design of the protocol", Muscle Nerve, 4, pp.186~197 (1981)[DOI]
- Ottenbacher KJ, "The stability and equivalence reliability of the functional independence measure for children (WeeFIM)", Dev Med Child Neurol, 38, pp.907~916 (1996)
- Lawton MP, "Assessment of older people: self-maintaining and instrumental activities of daily living", Gerontologist, 9, pp.179~186 (1969)[DOI]
- 정일영, "The Correlation Analysis of Functional Factors and Age with Duchenne Muscular Dystrophy", Annals of Rehabilitation Medicine, 36(1), pp.22~32 (2012), 대한재활의학회
- Ricotti V, "The NorthStar Ambulatory Assessment in Duchenne muscular dystrophy: considerations for the design of clinical trials", J Neurol Neurosurg Psychiatry, 87, pp.149~155 (2016)[DOI]
- Kinali M, "Management of scoliosis in Duchenne muscular dystrophy: a large 10-year retrospective study", Dev Med Child Neurol, 48, pp.513~518 (2006)[DOI]
- Kinali M, "Predictive factors for the development of scoliosis in Duchenne muscular dystrophy", Eur J Paediatr Neurol, 11, pp.160~166 (2007)[DOI]
- Mullender M, "A Dutch guideline for the treatment of scoliosis in neuromuscular disorders", Scoliosis, 3, pp.14~ (2008)[DOI]
- Weis R, "Introduction to abnormal child and adolescent psychology. 2nd ed." (2014), Sage Publications
- AAIDD User's Guide Work Group, "User's guide: to accompany the 11th edition of Intellectual disability: definition, classification, and systems of supports: applications for clinicians, educators, organizations providing supports, policymakers, family members and advocates, and health care professionals", American Association on Intellectual and Developmental Disabilitie, ~ (2012)
- Bittles AH, "The influence of intellectual disability on life expectancy", J Gerontol A Biol Sci Med Sci, 57, pp.M470~M472 (2002)[DOI]