Improving Effects of Brassica oleracea L. var. italica Sprout Extract on Alcoholic Liver Dysfunction
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Alcoholic fatty liver disorder has become a frequent health concern worldwide. To investigate the effects ofBrassica oleracea (B. oleracea) sprout extract (BOE), the present study was designed with alcoholic fatty liver in the rat. Initially, the effects of BOE on liver parameters were examined. Male rats were divided into five groups. The normal controlgroup was fed the normal diet, and the BOE group was fed the high fat diet and ethanol with/without BOE for 4 weeks. After4 weeks feeding period, rats were sacrificed and their livers and blood were used for fatty liver-related biomarkers analyses. As a result, BOE ameliorated fatty liver-related enzymes profiles in liver tissues and also reduced blood alcoholconcentration in rat model. We demonstrated that BOE protected the high fat diet and alcohol-induced fatty liver in ratmodel. Furthermore, BOE increased detoxificative abilities against alcohol.
Abstract
Alcoholic fatty liver disorder has become a frequent health concern worldwide. To investigate the effects ofBrassica oleracea (B. oleracea) sprout extract (BOE), the present study was designed with alcoholic fatty liver in the rat. Initially, the effects of BOE on liver parameters were examined. Male rats were divided into five groups. The normal controlgroup was fed the normal diet, and the BOE group was fed the high fat diet and ethanol with/without BOE for 4 weeks. After4 weeks feeding period, rats were sacrificed and their livers and blood were used for fatty liver-related biomarkers analyses. As a result, BOE ameliorated fatty liver-related enzymes profiles in liver tissues and also reduced blood alcoholconcentration in rat model. We demonstrated that BOE protected the high fat diet and alcohol-induced fatty liver in ratmodel. Furthermore, BOE increased detoxificative abilities against alcohol.
참고문헌 (23)
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