八物湯이 腦血流力學 變化에 미치는 效果
Effects of Palmul-Tang on the Change of Cerebral Hemodynamics in Rats
0
조회
0
다운로드
4
인용
0
참고문헌
초록
Abstract
The studywas designed to investigate the effects of Palmul-Tang(PMT) on the change of cerebral hemodynamics [regional cerebral blood flow(rCBF), pial arterial diameter(PAD) and mean arterial blood pressure(MABP)] in normal and cerebral ischemic rats. The change of rCBF and MABP were determinated by laser-doppler flowmetry(LDF), and the change of PAD was determinated by video-microscopy. The results in normal rats were as follows ; PMT significantly increased rCBF and PAD in a dose-dependent, and PMT increased MABP in a dose-dependent. This results were suggested that PMT significantly increased rCBF by dilating PAD. The results in cerebral ischemic rats were as follows ; Both rCBF and PAD were significantly and stably increased by PMT(10 ㎎/㎏, i.p.) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in control group. The present authors thought that PMT had an anti-ischemic effect through the improvement of cerebral hemodynamics.
참고문헌 (28)
- "The nitrous oxide method for the man", pp.476~483 (1948)
- "신경외과학", pp.150 275 284~156 279 285 (1997), 중앙문화사
- "Changes in extracellular calcium activity in cerebral ischemia", pp.203~209 (1981)
- "the importance of calcium", pp.269~277 (1982)
- "재관류 손상에서 뇌조직 아민 변동과 Free Radical과의 관련성", pp.2~8 (1990)
- "Polymorphonuclear leukocyteaccumulation in brain region with low blood flow during the early postischemic period", obre(vich), pp.246~17 253 (1986)
- "Influx of leukocytes and platelets in an evolving brain infarct"
- "최근 뇌졸중에 대한 역학적 고찰", pp.280~286 (1991)
- "A model of focal ischemic stoke in the rat", pp.738~17 743 (1986)
- "Reactivity of rat pial arterioles and venules to adenosine and carbon dioxide with detailed description of the closed cranial window technique in rats", pp.34~41 (1986)
- "Detailed description of a cranial window technique for acute and chronic experimentals", pp.308~6 317 (1975)
- "Reversible middle cerebral artery occlusion without craniectomy in rats", pp.84~20 91 (1989)
- "Correlation of continnous electroencephalograms with cerebral blood flow measurments during carotid endarterectomy", pp.672~4 683 (1973)
- "Relation between EEG regional cerebral blood flow and internal carotid artery pressure during carotid endarterectomy", pp.61~69 (1973)
- "Glutamate neurotoxicity and disease of the nervous system", pp.623~1 634 (1988)
- "Is oxidant damage relevant to Parkinson's disease traumatic injury or stroke", pp.23~33 (1989)
- "祛風導痰湯이 白鼠의 腦血流變化에 미치는 機轉硏究", pp.99~103 (2002)
- "淸暈化痰湯이 局所腦血流量에 미치는 實驗的 硏究", pp.316~321 (2002)
- "四君子湯 二陳湯 六君子湯이 腦血流力學 變動에 미치는 實驗的 硏究", pp.75~83 (2004)
- "牛黃淸心元이 중대뇌동맥 결찰로 유발된 뇌허혈에 미치는 영향", pp.78~89 (2001)
- "흰쥐의 중대뇌동맥 결찰로 유발된 腦虛血에서 星香正氣散과 藿香正氣散이 神經細胞에 미치는 효과", pp.142~150 (2001)
- "滋陰健脾湯加枳殼天麻가 腦細胞 및 腦血流力學 變動에 미치는 영향", pp.64~70 (2003)
- "天麻半夏湯이 腦血流力學에 미치는 影響"
- "八物湯이 알레르기 반응에 미치는 효과", pp.1075~1081 (2003)
- "팔물탕이 복강 마크로파지의 탐식능에 미치는 영향", pp.363~367 (1999)
- "八物湯이 생쥐 임신중기에 胸腺細胞 및 腹腔 Macrophage로부터 cytokines 생성에 미치는 영향", pp.412~418 (2001)
- "인체의 생리", pp.30 107~47 118 (1985), 서울대학교 출판부
- "Mechanisms of disease oxygen-derived free radicals in postischemic tissue injury", pp.159~163 (1985)